cryo-EM structure of human ATG9A in amphipols
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7jlo
Q-score: 0.536
Maeda S, Yamamoto H, Kinch LN, Garza CM, Takahashi S, Otomo C, Grishin NV, Forli S, Mizushima N, Otomo T
Nat Struct Mol Biol (2020) 27 pp. 1194-1201 [ DOI: doi:10.1038/s41594-020-00520-2 Pubmed: 33106659 ]
- Human atg9a in amphipols a8-35 (Cellular component from Homo sapiens)
- Autophagy-related protein 9a (66 kDa, Protein from Homo sapiens)
cryo-EM structure of human ATG9A in nanodiscs
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7jlp
Q-score: 0.552
Maeda S, Yamamoto H, Kinch LN, Garza CM, Takahashi S, Otomo C, Grishin NV, Forli S, Mizushima N, Otomo T
Nat Struct Mol Biol (2020) 27 pp. 1194-1201 [ DOI: doi:10.1038/s41594-020-00520-2 Pubmed: 33106659 ]
cryo-EM structure of human ATG9A in LMNG micelles
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7jlq
Q-score: 0.297
Maeda S, Yamamoto H, Kinch LN, Garza CM, Takahashi S, Otomo C, Grishin NV, Forli S, Mizushima N, Otomo T
Nat Struct Mol Biol (2020) 27 pp. 1194-1201 [ DOI: doi:10.1038/s41594-020-00520-2 Pubmed: 33106659 ]
- Human atg9a in lmng micelles (Cellular component from Homo sapiens)
- Autophagy-related protein 9a (66 kDa, Protein from Homo sapiens)
CD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6opn
Q-score: 0.386
Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB
Cell Rep (2020) 33 pp. 108428-108428 [ Pubmed: 33238117 DOI: doi:10.1016/j.celrep.2020.108428 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (58 kDa, Protein from Human immunodeficiency virus 1)
- T-cell surface glycoprotein cd4 (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cd4- and 17b-bound hiv-1 env b41 sosip in complex with small molecule go35 (50 kDa, Complex from Human immunodeficiency virus 1)
- 17b fragment antigen binding (Complex)
- [3'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-3-yl](piperidin-1-yl)methanone (347 Da, Ligand)
C3 symmetry reconstruction of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6opo
Q-score: 0.448
Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB
Cell Rep (2020) 33 pp. 108428-108428 [ Pubmed: 33238117 DOI: doi:10.1016/j.celrep.2020.108428 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Envelope glycoprotein gp160 (58 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 env b41 sosip in complex with soluble cd4, 17b fab and ddm (630 kDa, Complex from Human immunodeficiency virus 1)
- 17b fab light chain (23 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd4 (23 kDa, Protein from Homo sapiens)
- 17b fab heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Asymmetric reconstruction of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6opp
Q-score: 0.411
Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB
Cell Rep (2020) 33 pp. 108428-108428 [ Pubmed: 33238117 DOI: doi:10.1016/j.celrep.2020.108428 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Envelope glycoprotein gp160 (58 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 env b41 sosip in complex with soluble cd4, 17b fab and ddm (630 kDa, Complex from Human immunodeficiency virus 1)
- 17b fab light chain (23 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd4 (23 kDa, Protein from Homo sapiens)
- 17b fab heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6opq
Q-score: 0.363
Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB
Cell Rep (2020) 33 pp. 108428-108428 [ Pubmed: 33238117 DOI: doi:10.1016/j.celrep.2020.108428 ]
- Class 1 of cd4- and 17b-bound hiv-1 env b41 sosip incubated with lmng and small molecule go27 (50 kDa, Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (58 kDa, Protein from Human immunodeficiency virus 1)
- 17b fab light chain (23 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd4 (23 kDa, Protein from Homo sapiens)
- 17b fab heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6x5b
Q-score: 0.396
Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB
Cell Rep (2020) 33 pp. 108428-108428 [ Pubmed: 33238117 DOI: doi:10.1016/j.celrep.2020.108428 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- 17b fab light chain (23 kDa, Protein from Homo sapiens)
- T-cell surface glycoprotein cd4 (23 kDa, Protein from Homo sapiens)
- B41 hiv-1 env sosip in complex with soluble cd4, 17b fab, and small molecule go52 (630 kDa, Complex from Human immunodeficiency virus 1)
- 17b fab heavy chain (24 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp120 (58 kDa, Protein from Human immunodeficiency virus 1)
- N-(4'-methyl[1,1'-biphenyl]-4-yl)-1-oxa-7-azaspiro[3.5]nonane-7-carboxamide (336 Da, Ligand)
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 6x5c
Q-score: 0.341
Ozorowski G, Torres JL, Santos-Martins D, Forli S, Ward AB
Cell Rep (2020) 33 pp. 108428-108428 [ Pubmed: 33238117 DOI: doi:10.1016/j.celrep.2020.108428 ]
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (58 kDa, Protein from Human immunodeficiency virus 1)
- T-cell surface glycoprotein cd4 (23 kDa, Protein from Homo sapiens)
- B41 hiv-1 env sosip in complex with soluble cd4, 17b fab, and small molecule go52 (630 kDa, Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- N-(4'-methyl[1,1'-biphenyl]-4-yl)-1-oxa-7-azaspiro[3.5]nonane-7-carboxamide (336 Da, Ligand)