Cryo-EM structure of HCA2-Gi complex with LUF6283
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8ihh
Q-score: 0.521
Suzuki S, Tanaka K, Nishikawa K, Suzuki H, Oshima A, Fujiyoshi Y
Nat Commun (2023) 14 pp. 5899-5899 [ DOI: doi:10.1038/s41467-023-41650-7 Pubmed: 37736747 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
- Soluble cytochrome b562,hydroxycarboxylic acid receptor 2 (74 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Mus musculus)
- Multiprotein complex (Complex from Homo sapiens)
- 5-butyl-1~{h}-pyrazole-3-carboxylic acid (168 Da, Ligand)
- Scfv16 (26 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
Cryo-EM structure of HCA2-Gi complex with acifran
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 8ihi
Q-score: 0.523
Suzuki S, Tanaka K, Nishikawa K, Suzuki H, Oshima A, Fujiyoshi Y
Nat Commun (2023) 14 pp. 5899-5899 [ DOI: doi:10.1038/s41467-023-41650-7 Pubmed: 37736747 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
- Soluble cytochrome b562,hydroxycarboxylic acid receptor 2 (74 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Mus musculus)
- (5~{s})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid (218 Da, Ligand)
- Multiprotein complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
Cryo-EM structure of HCA3-Gi complex with acifran
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8ihj
Q-score: 0.507
Suzuki S, Tanaka K, Nishikawa K, Suzuki H, Oshima A, Fujiyoshi Y
Nat Commun (2023) 14 pp. 5899-5899 [ DOI: doi:10.1038/s41467-023-41650-7 Pubmed: 37736747 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Mus musculus)
- (5~{s})-5-methyl-4-oxidanylidene-5-phenyl-furan-2-carboxylic acid (218 Da, Ligand)
- Multiprotein complex (Complex from Homo sapiens)
- Soluble cytochrome b562,hydroxycarboxylic acid receptor 3 (60 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
Cryo-EM structure of HCA3-Gi complex with acifran (local)
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8ihk
Q-score: 0.472
Suzuki S, Tanaka K, Nishikawa K, Suzuki H, Oshima A, Fujiyoshi Y
Nat Commun (2023) 14 pp. 5899-5899 [ DOI: doi:10.1038/s41467-023-41650-7 Pubmed: 37736747 ]
Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A
Resolution: 3.76 Å
EM Method: Single-particle
Fitted PDBs: 8huj
Q-score: 0.406
Imai S, Suzuki H, Fujiyoshi Y, Shimada I
Nat Commun (2023) 14 pp. 4977-4977 [ DOI: doi:10.1038/s41467-023-40582-6 Pubmed: 37640715 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Eukaryotic initiation factor 4a-i (48 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 4 gamma 1 (31 kDa, Protein from Homo sapiens)
- Ires rna (j-k-st) (34 kDa, RNA from Encephalomyocarditis virus)
- Ternary complex of the j-k-st region of emcv ires with eif4a and eif4g-heat1 (Complex from Homo sapiens)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8j7r
Q-score: 0.407
Imai S, Suzuki H, Fujiyoshi Y, Shimada I
Nat Commun (2023) 14 pp. 4977-4977 [ DOI: doi:10.1038/s41467-023-40582-6 Pubmed: 37640715 ]
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Eukaryotic translation initiation factor 4 gamma 1 (31 kDa, Protein from Homo sapiens)
- Ires rna (j-k-st) (34 kDa, RNA from Encephalomyocarditis virus)
- Ternary complex of the j-k-st region of emcv ires with eif4a and eif4g-heat1 (Complex from Homo sapiens)
Cryo-EM structure of human pannexin-1 in a nanodisc
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7f8j
Q-score: 0.48
Kuzuya M, Hirano H, Hayashida K, Watanabe M, Kobayashi K, Terada T, Mahmood MI, Tama F, Tani K, Fujiyoshi Y, Oshima A
Sci Signal (2022) 15 pp. eabg6941-eabg6941 [ Pubmed: 35133866 DOI: doi:10.1126/scisignal.abg6941 ]
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Heptamar of human pannexin-1 channel in a nanodisc (Complex from Homo sapiens)
- Pannexin-1 (48 kDa, Protein from Homo sapiens)
Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7f8n
Q-score: 0.488
Kuzuya M, Hirano H, Hayashida K, Watanabe M, Kobayashi K, Terada T, Mahmood MI, Tama F, Tani K, Fujiyoshi Y, Oshima A
Sci Signal (2022) 15 pp. eabg6941-eabg6941 [ Pubmed: 35133866 DOI: doi:10.1126/scisignal.abg6941 ]
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Human pannexin-1 (Complex from Homo sapiens)
- Pannexin-1 (48 kDa, Protein from Homo sapiens)
Cryo-EM structure of the C-terminal deletion mutant of human PANX1 in a nanodisc
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7f8o
Q-score: 0.444
Kuzuya M, Hirano H, Hayashida K, Watanabe M, Kobayashi K, Terada T, Mahmood MI, Tama F, Tani K, Fujiyoshi Y, Oshima A
Sci Signal (2022) 15 pp. eabg6941-eabg6941 [ Pubmed: 35133866 DOI: doi:10.1126/scisignal.abg6941 ]
- 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (760 Da, Ligand)
- Heptamar of human pannexin-1 channel in a nanodisc (Complex from Homo sapiens)
- Pannexin-1 (48 kDa, Protein from Homo sapiens)
Cryo-EM structure of a human ATP11C-CDC50A flippase in E1AlF-ADP state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7bsq
Q-score: 0.567
Nakanishi H, Nishizawa T, Segawa K, Nureki O, Fujiyoshi Y, Nagata S, Abe K
Cell Rep (2020) 32 pp. 108208-108208 [ DOI: doi:10.1016/j.celrep.2020.108208 Pubmed: 32997992 ]
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Human atp11c-cdc50a flippase (180 kDa, Complex from Homo sapiens)
- Atp11c (124 kDa, Protein from Homo sapiens)
- Cdc50a (40 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)