Closed state of SARS-CoV-2 BA.2 variant spike protein
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8d55
Q-score: 0.434
One RBD-up state of SARS-CoV-2 BA.2 variant spike protein
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8d56
Q-score: 0.438
Middle state of SARS-CoV-2 BA.2 variant spike protein
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8d5a
Q-score: 0.414
G32A4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7swn
Q-score: 0.358
Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC
Sci Immunol (2022) 7 pp. eabo3425-eabo3425 [ Pubmed: 35536154 DOI: doi:10.1126/sciimmunol.abo3425 ]
- C98c7 fab in complex with wt sars-cov-2 rbd (Complex)
- G32a4 fab light chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- G32a4 fab heavy chain (24 kDa, Protein from Homo sapiens)
C98C7 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7swo
Q-score: 0.427
Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC
Sci Immunol (2022) 7 pp. eabo3425-eabo3425 [ DOI: doi:10.1126/sciimmunol.abo3425 Pubmed: 35536154 ]
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- C98c7 fab heavy chain (23 kDa, Protein from Homo sapiens)
- C98c7 fab in complex with wt sars-cov-2 rbd (Complex)
- C98c7 fab light chain (23 kDa, Protein from Homo sapiens)
G32Q4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7swp
Q-score: 0.341
Windsor IW, Tong P, Lavidor O, Moghaddam AS, McKay LGA, Gautam A, Chen Y, MacDonald EA, Yoo DK, Griffths A, Wesemann DR, Harrison SC
Sci Immunol (2022) 7 pp. eabo3425-eabo3425 [ DOI: doi:10.1126/sciimmunol.abo3425 Pubmed: 35536154 ]
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- G32q4 fab light chain (22 kDa, Protein from Homo sapiens)
- C98c7 fab in complex with wt sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- G32q4 fab heavy chain (25 kDa, Protein from Homo sapiens)
Structural and functional impact by SARS-CoV-2 Omicron spike mutations
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7tnw
Q-score: 0.44
Structural and functional impact by SARS-CoV-2 Omicron spike mutations
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7to4
Q-score: 0.394
One RBD-up 1 of pre-fusion SARS-CoV-2 Delta variant spike protein
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7sbl
Q-score: 0.394
Zhang J, Xiao T, Cai Y, Lavine CL, Peng H, Zhu H, Anand K, Tong P, Gautam A, Mayer ML, Walsh Jr RM, Rits-Volloch S, Wesemann DR, Yang W, Seaman MS, Lu J, Chen B
Science (2021) 374 pp. 1353-1360 [ DOI: doi:10.1126/science.abl9463 Pubmed: 34698504 ]
One RBD-up 2 of pre-fusion SARS-CoV-2 Gamma variant spike protein
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7sbt
Q-score: 0.269
Zhang J, Xiao T, Cai Y, Lavine CL, Peng H, Zhu H, Anand K, Tong P, Gautam A, Mayer ML, Walsh Jr RM, Rits-Volloch S, Wesemann DR, Yang W, Seaman MS, Lu J, Chen B
Science (2021) 374 pp. 1353-1360 [ DOI: doi:10.1126/science.abl9463 Pubmed: 34698504 ]