Cryo-EM structure of the inner MKLN1 dimer from an autoinhibited MKLN1 tetramer
Resolution: 3.27 Å
EM Method: Single-particle
Fitted PDBs: 8ttq
Q-score: 0.398
Barbulescu P, Chana CK, Wong MK, Ben Makhlouf I, Bruce JP, Feng Y, Keszei AFA, Wong C, Mohamad-Ramshan R, McGary LC, Kashem MA, Ceccarelli DF, Orlicky S, Fang Y, Kuang H, Mazhab-Jafari M, Pezo RC, Bhagwat AS, Pugh TJ, Gingras AC, Sicheri F, Martin A
Nat Commun (2024) 15 pp. 7541-7541 [ DOI: doi:10.1038/s41467-024-52009-x Pubmed: 39215025 ]
CryoEM structure of the HisRS-like domain of human GCN2
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8t7t
Q-score: 0.45
Yin JZ, Keszei AFA, Houliston S, Filandr F, Beenstock J, Daou S, Kitaygorodsky J, Schriemer DC, Mazhab-Jafari MT, Gingras AC, Sicheri F
Structure (2024) 32 pp. 795-811.e6 [ DOI: doi:10.1016/j.str.2024.02.021 Pubmed: 38531363 ]
- Eif-2-alpha kinase gcn2 (187 kDa, Protein from Homo sapiens)
- Dimeric hisrs-like domain of human gcn2 (Complex from Homo sapiens)
Structure of porcine V-ATPase with mEAK7 and SidK, Rotary state 2
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7u8o
Q-score: 0.371
Tan YZ, Abbas YM, Wu JZ, Wu D, Keon KA, Hesketh GG, Bueler SA, Gingras AC, Robinson CV, Grinstein S, Rubinstein JL
Life Sci Alliance (2022) 5 [ Pubmed: 35794005 DOI: doi:10.26508/lsa.202201527 ]
- Tldc protein meak-7 (50 kDa, Protein from Sus scrofa)
- V-type proton atpase proteolipid subunit (15 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit f (13 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit d (28 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit a (96 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit (40 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit c (44 kDa, Protein from Sus scrofa)
- Atpase h+ transporting accessory protein 1 (51 kDa, Protein from Sus scrofa)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit g (13 kDa, Protein from Sus scrofa)
- Ribonuclease kappa (11 kDa, Protein from Sus scrofa)
- Bacterial effector protein sidk (38 kDa, Protein from Legionella pneumophila)
- V-type proton atpase 21 kda proteolipid subunit isoform 1 (21 kDa, Protein from Sus scrofa)
- Atpase h(+)-transporting lysosomal accessory protein 2 (39 kDa, Protein from Sus scrofa)
- Vacuolar proton pump subunit b (57 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit (9 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit h (55 kDa, Protein from Sus scrofa)
- V-atpase in complex with recombinant sidk and recombinant meak-7 (Complex from Sus scrofa)
Structure of porcine kidney V-ATPase with SidK, Rotary State 1
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7u8p
Q-score: 0.334
Tan YZ, Abbas YM, Wu JZ, Wu D, Keon KA, Hesketh GG, Bueler SA, Gingras AC, Robinson CV, Grinstein S, Rubinstein JL
Life Sci Alliance (2022) 5 [ Pubmed: 35794005 DOI: doi:10.26508/lsa.202201527 ]
- V-type proton atpase proteolipid subunit (15 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit f (13 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit d (28 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit a (96 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Porcine kidney v-atpase with sidk, rotary state 1 (Complex from Sus scrofa)
- V-type proton atpase subunit (40 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit c (44 kDa, Protein from Sus scrofa)
- Atpase h+ transporting accessory protein 1 (51 kDa, Protein from Sus scrofa)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit g (13 kDa, Protein from Sus scrofa)
- Ribonuclease kappa (11 kDa, Protein from Sus scrofa)
- Bacterial effector protein sidk (38 kDa, Protein from Legionella pneumophila)
- V-type proton atpase 21 kda proteolipid subunit isoform 1 (21 kDa, Protein from Sus scrofa)
- Atpase h(+)-transporting lysosomal accessory protein 2 (39 kDa, Protein from Sus scrofa)
- Vacuolar proton pump subunit b (57 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit (9 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit h (55 kDa, Protein from Sus scrofa)
Structure of porcine kidney V-ATPase with SidK, Rotary State 2
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7u8q
Q-score: 0.247
Tan YZ, Abbas YM, Wu JZ, Wu D, Keon KA, Hesketh GG, Bueler SA, Gingras AC, Robinson CV, Grinstein S, Rubinstein JL
Life Sci Alliance (2022) 5 [ Pubmed: 35794005 DOI: doi:10.26508/lsa.202201527 ]
- V-type proton atpase proteolipid subunit (15 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit f (13 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit d (28 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit a (96 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase subunit (40 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit c (44 kDa, Protein from Sus scrofa)
- Atpase h+ transporting accessory protein 1 (51 kDa, Protein from Sus scrofa)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit g (13 kDa, Protein from Sus scrofa)
- Ribonuclease kappa (11 kDa, Protein from Sus scrofa)
- Bacterial effector protein sidk (38 kDa, Protein from Legionella pneumophila)
- V-type proton atpase 21 kda proteolipid subunit isoform 1 (21 kDa, Protein from Sus scrofa)
- Atpase h(+)-transporting lysosomal accessory protein 2 (39 kDa, Protein from Sus scrofa)
- Porcine kidney v-atpase with sidk, rotary state 2 (Complex from Sus scrofa)
- Vacuolar proton pump subunit b (57 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit (9 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit h (55 kDa, Protein from Sus scrofa)
Structure of porcine kidney V-ATPase with SidK, Rotary State 3
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7u8r
Q-score: 0.301
Tan YZ, Abbas YM, Wu JZ, Wu D, Keon KA, Hesketh GG, Bueler SA, Gingras AC, Robinson CV, Grinstein S, Rubinstein JL
Life Sci Alliance (2022) 5 [ Pubmed: 35794005 DOI: doi:10.26508/lsa.202201527 ]
- V-type proton atpase proteolipid subunit (15 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit f (13 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit d (28 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit a (96 kDa, Protein from Sus scrofa)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Porcine kidney v-atpase with sidk, rotary state 3 (Complex from Sus scrofa)
- V-type proton atpase subunit (40 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit c (44 kDa, Protein from Sus scrofa)
- Atpase h+ transporting accessory protein 1 (51 kDa, Protein from Sus scrofa)
- V-type proton atpase catalytic subunit a (68 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit g (13 kDa, Protein from Sus scrofa)
- Ribonuclease kappa (11 kDa, Protein from Sus scrofa)
- Bacterial effector protein sidk (38 kDa, Protein from Legionella pneumophila)
- V-type proton atpase 21 kda proteolipid subunit isoform 1 (21 kDa, Protein from Sus scrofa)
- Atpase h(+)-transporting lysosomal accessory protein 2 (39 kDa, Protein from Sus scrofa)
- Vacuolar proton pump subunit b (57 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit (9 kDa, Protein from Sus scrofa)
- V-type proton atpase subunit h (55 kDa, Protein from Sus scrofa)