Structure of Expanded C. elegans TMC-1 complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7usw
Q-score: 0.508
Jeong H, Clark S, Goehring A, Dehghani-Ghahnaviyeh S, Rasouli A, Tajkhorshid E, Gouaux E
Nature (2022) 610 pp. 796-803 [ Pubmed: 36224384 DOI: doi:10.1038/s41586-022-05314-8 ]
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Transmembrane channel-like protein 1 (147 kDa, Protein from Caenorhabditis elegans)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Undecan-1-ol (172 Da, Ligand)
- Native tmc-1 complex (430 kDa, Complex from Caenorhabditis elegans)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Hexadecane (226 Da, Ligand)
- Calmyrin (calcium and integrin binding protein) homolog (23 kDa, Protein from Caenorhabditis elegans)
- Cholesterol (386 Da, Ligand)
- Transmembrane inner ear expressed protein (12 kDa, Protein from Caenorhabditis elegans)
- Dodecane (170 Da, Ligand)
Structure of Contracted C. elegans TMC-1 complex
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 7usx
Q-score: 0.48
Jeong H, Clark S, Goehring A, Dehghani-Ghahnaviyeh S, Rasouli A, Tajkhorshid E, Gouaux E
Nature (2022) 610 pp. 796-803 [ Pubmed: 36224384 DOI: doi:10.1038/s41586-022-05314-8 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Transmembrane channel-like protein 1 (147 kDa, Protein from Caenorhabditis elegans)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Native tmc-1 complex (430 kDa, Complex from Caenorhabditis elegans)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Hexadecane (226 Da, Ligand)
- Calmyrin (calcium and integrin binding protein) homolog (23 kDa, Protein from Caenorhabditis elegans)
- Cholesterol (386 Da, Ligand)
- Transmembrane inner ear expressed protein (12 kDa, Protein from Caenorhabditis elegans)
- Dodecane (170 Da, Ligand)
Structure of C. elegans TMC-1 complex with ARRD-6
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 7usy
Q-score: 0.355
Jeong H, Clark S, Goehring A, Dehghani-Ghahnaviyeh S, Rasouli A, Tajkhorshid E, Gouaux E
Nature (2022) 610 pp. 796-803 [ Pubmed: 36224384 DOI: doi:10.1038/s41586-022-05314-8 ]
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Transmembrane channel-like protein 1 (147 kDa, Protein from Caenorhabditis elegans)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Native tmc-1 complex (480 kDa, Complex from Caenorhabditis elegans)
- Arrestin domain protein (53 kDa, Protein from Caenorhabditis elegans)
- Calmyrin (calcium and integrin binding protein) homolog (23 kDa, Protein from Caenorhabditis elegans)
- Transmembrane inner ear expressed protein (12 kDa, Protein from Caenorhabditis elegans)