Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 5uow
Q-score: 0.206
Lu W, Du J, Goehring A, Gouaux E
Science (2017) 355 [ Pubmed: 28232581 DOI: doi:10.1126/science.aal3729 ]
- Ionotropic glutamate receptor subunit nr2b (94 kDa, Protein from Xenopus laevis)
- N-methyl-d-aspartate receptor subunit nr1-8a (91 kDa, Protein from Xenopus laevis)
- (5s,10r)-5-methyl-10,11-dihydro-5h-5,10-epiminodibenzo[a,d][7]annulene (221 Da, Ligand)
- Membrane protein (Complex from Xenopus laevis)
- N-methyl-d-aspartate receptor subunit nr2a (93 kDa, Protein from Xenopus laevis)
- Glun2b-specific fab, termed 11d1 (18 kDa, Protein from Mus musculus)
- Glutamic acid (147 Da, Ligand)
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 5up2
Q-score: 0.16
Lu W, Du J, Goehring A, Gouaux E
Science (2017) 355 [ Pubmed: 28232581 DOI: doi:10.1126/science.aal3729 ]
- Ionotropic glutamate receptor subunit nr2b (94 kDa, Protein from Xenopus laevis)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Membrane protein (Complex from Xenopus laevis)
- N-methyl-d-aspartate receptor subunit nr2a (93 kDa, Protein from Xenopus laevis)
- Glun2b-specific fab, termed 11d1 (18 kDa, Protein from Mus musculus)
- N-methyl-d-aspartate receptor subunit nr1-8a (94 kDa, Protein from Xenopus laevis)
Lu W, Du J, Goehring A, Gouaux E
Science (2017) 355 [ Pubmed: 28232581 DOI: doi:10.1126/science.aal3729 ]
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine-bound conformation
Resolution: 7.0 Å
EM Method: Single-particle
Fitted PDBs: 5iou
Q-score: 0.223
Zhu S, Stein RA, Yoshioka C, Lee CH, Goehring A, Mchaourab HS, Gouaux E
Cell (2016) 165 pp. 704-714 [ Pubmed: 27062927 DOI: doi:10.1016/j.cell.2016.03.028 ]
- N-methyl-d-aspartate receptor subunit nr1-8a (92 kDa, Protein from Xenopus laevis)
- Glun1-glun2b nmda receptor (Cellular component from Xenopus laevis)
- Ionotropic glutamate receptor subunit nr2b (93 kDa, Protein from Xenopus laevis)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
Resolution: 7.5 Å
EM Method: Single-particle
Fitted PDBs: 5iov
Q-score: 0.203
Zhu S, Stein RA, Yoshioka C, Lee CH, Goehring A, Mchaourab HS, Gouaux E
Cell (2016) 165 pp. 704-714 [ Pubmed: 27062927 DOI: doi:10.1016/j.cell.2016.03.028 ]
- Glun1-glun2b receptor in the complex with glycine and glutamate plus allosteric inhibitor ro25-6981 (Cellular component from Xenopus laevis)
- N-methyl-d-aspartate receptor subunit nr1-8a (92 kDa, Protein from Xenopus laevis)
- Ionotropic glutamate receptor subunit nr2b (93 kDa, Protein from Xenopus laevis)
- Glutamic acid (147 Da, Ligand)
- 4-[(1r,2s)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol (339 Da, Ligand)
- Glycine (75 Da, Ligand)
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 2
Resolution: 13.5 Å
EM Method: Single-particle
Fitted PDBs: 5ipq
Q-score: 0.085
Zhu S, Stein RA, Yoshioka C, Lee CH, Goehring A, Mchaourab HS, Gouaux E
Cell (2016) 165 pp. 704-714 [ Pubmed: 27062927 DOI: doi:10.1016/j.cell.2016.03.028 ]
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 3
Resolution: 14.1 Å
EM Method: Single-particle
Fitted PDBs: 5ipr
Q-score: 0.086
Zhu S, Stein RA, Yoshioka C, Lee CH, Goehring A, Mchaourab HS, Gouaux E
Cell (2016) 165 pp. 704-714 [ Pubmed: 27062927 DOI: doi:10.1016/j.cell.2016.03.028 ]
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 4
Resolution: 13.5 Å
EM Method: Single-particle
Fitted PDBs: 5ips
Q-score: 0.089
Zhu S, Stein RA, Yoshioka C, Lee CH, Goehring A, Mchaourab HS, Gouaux E
Cell (2016) 165 pp. 704-714 [ Pubmed: 27062927 DOI: doi:10.1016/j.cell.2016.03.028 ]
Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 5
Resolution: 14.1 Å
EM Method: Single-particle
Fitted PDBs: 5ipt
Q-score: 0.08
Zhu S, Stein RA, Yoshioka C, Lee CH, Goehring A, Mchaourab HS, Gouaux E
Cell (2016) 165 pp. 704-714 [ Pubmed: 27062927 DOI: doi:10.1016/j.cell.2016.03.028 ]