Leishmania tarentolae proteasome 20S subunit complexed with GSK3494245
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6qm7
Q-score: 0.607
Wyllie S, Brand S, Thomas M, De Rycker M, Chung CW, Pena I, Bingham RP, Bueren-Calabuig JA, Cantizani J, Cebrian D, Craggs PD, Ferguson L, Goswami P, Hobrath J, Howe J, Jeacock L, Ko EJ, Korczynska J, MacLean L, Manthri S, Martinez MS, Mata-Cantero L, Moniz S, Nuhs A, Osuna-Cabello M, Pinto E, Riley J, Robinson S, Rowland P, Simeons FRC, Shishikura Y, Spinks D, Stojanovski L, Thomas J, Thompson S, Viayna Gaza E, Wall RJ, Zuccotto F, Horn D, Ferguson MAJ, Fairlamb AH, Fiandor JM, Martin J, Gray DW, Miles TJ, Gilbert IH, Read KD, Marco M, Wyatt PG
PNAS (2019) 116 pp. 9318-9323 [ DOI: doi:10.1073/pnas.1820175116 Pubmed: 30962368 ]
- Proteasome alpha4 chain (27 kDa, Protein from Leishmania tarentolae)
- Water (18 Da, Ligand)
- Proteasome alpha6 chain (47 kDa, Protein from Leishmania tarentolae)
- Proteasome beta2 chain (27 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha7 chain (25 kDa, Protein from Leishmania tarentolae)
- ~{n}-[4-fluoranyl-3-(3-morpholin-4-ylimidazo[1,2-a]pyrimidin-7-yl)phenyl]pyrrolidine-1-carboxamide (410 Da, Ligand)
- Proteasome beta1 chain (30 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha3 chain (32 kDa, Protein from Leishmania tarentolae)
- Proteasome beta4 chain (23 kDa, Protein from Leishmania tarentolae)
- Proteasome beta3 chain (22 kDa, Protein from Leishmania tarentolae)
- Proteasome beta6 chain (37 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha2 chain (25 kDa, Protein from Leishmania tarentolae)
- Proteasome 20s subunit (Complex from Leishmania tarentolae)
- Proteasome alpha5 chain (38 kDa, Protein from Leishmania tarentolae)
- Proteasome beta7 chain (24 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha1 chain (27 kDa, Protein from Leishmania tarentolae)
- Proteasome beta5 chain (33 kDa, Protein from Leishmania tarentolae)
Leishmania tarentolae proteasome 20S subunit apo structure
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6qm8
Q-score: 0.516
Wyllie S, Brand S, Thomas M, De Rycker M, Chung CW, Pena I, Bingham RP, Bueren-Calabuig JA, Cantizani J, Cebrian D, Craggs PD, Ferguson L, Goswami P, Hobrath J, Howe J, Jeacock L, Ko EJ, Korczynska J, MacLean L, Manthri S, Martinez MS, Mata-Cantero L, Moniz S, Nuhs A, Osuna-Cabello M, Pinto E, Riley J, Robinson S, Rowland P, Simeons FRC, Shishikura Y, Spinks D, Stojanovski L, Thomas J, Thompson S, Viayna Gaza E, Wall RJ, Zuccotto F, Horn D, Ferguson MAJ, Fairlamb AH, Fiandor JM, Martin J, Gray DW, Miles TJ, Gilbert IH, Read KD, Marco M, Wyatt PG
PNAS (2019) 116 pp. 9318-9323 [ DOI: doi:10.1073/pnas.1820175116 Pubmed: 30962368 ]
- Proteasome alpha4 chain (27 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha6 chain (47 kDa, Protein from Leishmania tarentolae)
- Proteasome beta2 chain (27 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha7 chain (25 kDa, Protein from Leishmania tarentolae)
- Proteasome beta1 chain (30 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha3 chain (32 kDa, Protein from Leishmania tarentolae)
- Proteasome beta4 chain (23 kDa, Protein from Leishmania tarentolae)
- Proteasome beta3 chain (22 kDa, Protein from Leishmania tarentolae)
- Proteasome beta6 chain (37 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha2 chain (25 kDa, Protein from Leishmania tarentolae)
- Proteasome 20s subunit (Complex from Leishmania tarentolae)
- Proteasome alpha5 chain (38 kDa, Protein from Leishmania tarentolae)
- Proteasome beta7 chain (24 kDa, Protein from Leishmania tarentolae)
- Proteasome alpha1 chain (27 kDa, Protein from Leishmania tarentolae)
- Proteasome beta5 chain (33 kDa, Protein from Leishmania tarentolae)