Chimaera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 7z5c
Q-score: 0.424
Zaccai NR, Kadlecova Z, Dickson VK, Korobchevskaya K, Kamenicky J, Kovtun O, Umasankar PK, Wrobel AG, Kaufman JGG, Gray SR, Qu K, Evans PR, Fritzsche M, Sroubek F, Honing S, Briggs JAG, Kelly BT, Owen DJ, Traub LM
Sci Adv (2022) 8 pp. eabn2018-eabn2018 [ Pubmed: 35486718 DOI: doi:10.1126/sciadv.abn2018 ]
- Ap-2 complex subunit mu (49 kDa, Protein from Rattus norvegicus)
- Ap-2 complex subunit sigma (17 kDa, Protein from Mus musculus)
- Ap-2 complex subunit beta (66 kDa, Protein from Homo sapiens)
- Ap-2 complex subunit alpha-2 (69 kDa, Protein from Rattus norvegicus)
- Ap2 core complex (203 kDa, Complex from Escherichia coli 'BL21-Gold(DE3)pLysS AG')
Chimaera of AP2 with FCHO2 linker domain, N1-N2 enriched population
Zaccai NR, Kadlecova Z, Dickson VK, Korobchevskaya K, Kamenicky J, Kovtun O, Umasankar PK, Wrobel AG, Kaufman JGG, Gray SR, Qu K, Evans PR, Fritzsche M, Sroubek F, Honing S, Briggs JAG, Kelly BT, Owen DJ, Traub LM
Sci Adv (2022) 8 pp. eabn2018-eabn2018 [ Pubmed: 35486718 DOI: doi:10.1126/sciadv.abn2018 ]
- Ap2 core complex (203 kDa, Complex from Rattus norvegicus)
AP2 adaptor protein recruited on the membrane in the presence of FCHO2 linker
Zaccai NR, Kadlecova Z, Dickson VK, Korobchevskaya K, Kamenicky J, Kovtun O, Umasankar PK, Wrobel AG, Kaufman JGG, Gray SR, Qu K, Evans PR, Fritzsche M, Sroubek F, Honing S, Briggs JAG, Kelly BT, Owen DJ, Traub LM
Sci Adv (2022) 8 pp. eabn2018-eabn2018 [ Pubmed: 35486718 DOI: doi:10.1126/sciadv.abn2018 ]
- Ap-2 complex subunit alpha-2 (Protein from Rattus norvegicus)
- Clathrin adaptor protein ap2 recruited on the membrane in the presence of interdomain linker of fcho2 (Complex from Homo sapiens)
- Ap-2 complex subunit beta (Protein from Homo sapiens)
- Ap-2 complex subunit sigma (Protein from Mus musculus)
- Fcho2: f-bar domain only protein 2 interdomain linker (Protein from Homo sapiens)
- Ap-2 complex subunit mu (Protein from Rattus norvegicus)
AP2 on the membrane without cargo peptide
Zaccai NR, Kadlecova Z, Dickson VK, Korobchevskaya K, Kamenicky J, Kovtun O, Umasankar PK, Wrobel AG, Kaufman JGG, Gray SR, Qu K, Evans PR, Fritzsche M, Sroubek F, Honing S, Briggs JAG, Kelly BT, Owen DJ, Traub LM
Sci Adv (2022) 8 pp. eabn2018-eabn2018 [ Pubmed: 35486718 DOI: doi:10.1126/sciadv.abn2018 ]
- Ap-2 complex subunit alpha-2 (Protein from Rattus norvegicus)
- Clathrin adaptor protein ap2 recruited on the membrane in the absence of a cargo peptide. (Complex from Homo sapiens)
- Ap-2 complex subunit beta (Protein from Homo sapiens)
- Ap-2 complex subunit sigma (Protein from Mus musculus)
- Ap-2 complex subunit mu (Protein from Rattus norvegicus)