SARS-CoV-2 VFLIP spike boung to 2 Ab12 Fab fragments
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ DOI: doi:10.1038/s41467-022-33030-4 Pubmed: 36192374 ]
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7t3m
Q-score: 0.505
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ DOI: doi:10.1038/s41467-022-33030-4 Pubmed: 36192374 ]
- Spike glycoprotein (127 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody 2-7 scfv (30 kDa, Protein from Escherichia coli)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of sars cov-2 s, spike glycoprotein, variant d614g with antibody 2-7 scfv (Complex)
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ DOI: doi:10.1038/s41467-022-33030-4 Pubmed: 36192374 ]
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ DOI: doi:10.1038/s41467-022-33030-4 Pubmed: 36192374 ]
SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7t67
Q-score: 0.399
Chang MR, Tomasovic L, Kuzmina NA, Ronk AJ, Byrne PO, Johnson R, Storm N, Olmedillas E, Hou YJ, Schafer A, Leist SR, Tse LV, Ke H, Coherd C, Nguyen K, Kamkaew M, Honko A, Zhu Q, Alter G, Saphire EO, McLellan JS, Griffiths A, Baric RS, Bukreyev A, Marasco WA
Nat Commun (2022) 13 pp. 5814-5814 [ DOI: doi:10.1038/s41467-022-33030-4 Pubmed: 36192374 ]
IMM20190 Fab complex with SARS-CoV-2 Spike Trimer
Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK
Sci Immunol (2022) 7 pp. eabl9943-eabl9943 [ DOI: doi:10.1126/sciimmunol.abl9943 Pubmed: 35771946 ]
IMM20253 Fab complex with Trimer Spike protein of SARS-CoV-2 virus
Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK
Sci Immunol (2022) 7 pp. eabl9943-eabl9943 [ DOI: doi:10.1126/sciimmunol.abl9943 Pubmed: 35771946 ]
IMM20253 Fab complex with Spike monomer
Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK
Sci Immunol (2022) 7 pp. eabl9943-eabl9943 [ DOI: doi:10.1126/sciimmunol.abl9943 Pubmed: 35771946 ]
IMM20184 Fab complex with SARS-CoV-2 Spike Trimer
Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK
Sci Immunol (2022) 7 pp. eabl9943-eabl9943 [ DOI: doi:10.1126/sciimmunol.abl9943 Pubmed: 35771946 ]
IMM20184 and IMM20253 Fabs in ternary complex with SARS-CoV-2 receptor binding domain
Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK
Sci Immunol (2022) 7 pp. eabl9943-eabl9943 [ DOI: doi:10.1126/sciimmunol.abl9943 Pubmed: 35771946 ]
- Sars-cov-2 rbd (Complex from Severe acute respiratory syndrome coronavirus)
- Imm20253 fab (Complex from Homo sapiens)
- Imm20184 fab (Complex from Homo sapiens)
- Imm20184 and imm20253 fabs in ternary complex with rbd of sars-cov-2 (Complex from Severe acute respiratory syndrome coronavirus)