PDCoV spike glycoprotein ectodomain in complex with the 22C10 antibody Fab fragment
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8r9w
Q-score: 0.531
Du W, Debski-Antoniak O, Drabek D, van Haperen R, van Dortmondt M, van der Lee J, Drulyte I, van Kuppeveld FJM, Grosveld F, Hurdiss DL, Bosch BJ
Nat Commun (2024) 15 pp. 5330-5330 [ DOI: doi:10.1038/s41467-024-49693-0 Pubmed: 38909062 ]
- 22c10 antibody light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pdcov spike glycoprotein ectodomain in complex with the 22c10 antibody fab fragment (520 kDa, Complex from Homo sapiens)
- Spike protein (119 kDa, Protein from Deltacoronavirus)
- 22c10 antibody heavy chain (13 kDa, Protein from Homo sapiens)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8r9x
Q-score: 0.542
Du W, Debski-Antoniak O, Drabek D, van Haperen R, van Dortmondt M, van der Lee J, Drulyte I, van Kuppeveld FJM, Grosveld F, Hurdiss DL, Bosch BJ
Nat Commun (2024) 15 pp. 5330-5330 [ DOI: doi:10.1038/s41467-024-49693-0 Pubmed: 38909062 ]
- Local refinement of the pdcov spike glycoprotein ectodomain in complex with the 22c10 antibody fab fragment (78 kDa, Complex from Homo sapiens)
- 22c10 antibody light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pdcov spike glycoprotein s1a domain (119 kDa, Protein from Homo sapiens)
- 22c10 antibody heavy chain (13 kDa, Protein from Homo sapiens)
S1B domain of the PDCoV spike glycoprotein in complex with the 67B12 and 42H3 antibody Fab fragments
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8r9y
Q-score: 0.522
Du W, Debski-Antoniak O, Drabek D, van Haperen R, van Dortmondt M, van der Lee J, Drulyte I, van Kuppeveld FJM, Grosveld F, Hurdiss DL, Bosch BJ
Nat Commun (2024) 15 pp. 5330-5330 [ DOI: doi:10.1038/s41467-024-49693-0 Pubmed: 38909062 ]
- 42h3 antibody heavy chain (23 kDa, Protein from Homo sapiens)
- Spike protein (22 kDa, Protein from Porcine deltacoronavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 42h3 antibody light chain (23 kDa, Protein from Homo sapiens)
- 67b12 antibody light chain (23 kDa, Protein from Homo sapiens)
- Pdcov spike s1b domain in complex with the 67b12 and 42h3 antibody fab fragments (105 kDa, Complex from Homo sapiens)
- 67b12 antibody heavy chain (22 kDa, Protein from Homo sapiens)
S1B domain of the PDCoV spike glycoprotein in complex with the 67B12 and 46E6 antibody Fab fragments
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8r9z
Q-score: 0.539
Du W, Debski-Antoniak O, Drabek D, van Haperen R, van Dortmondt M, van der Lee J, Drulyte I, van Kuppeveld FJM, Grosveld F, Hurdiss DL, Bosch BJ
Nat Commun (2024) 15 pp. 5330-5330 [ DOI: doi:10.1038/s41467-024-49693-0 Pubmed: 38909062 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 46e6 antibody heavy chain (23 kDa, Protein from Homo sapiens)
- 67b12 antibody light chain (23 kDa, Protein from Homo sapiens)
- Spike protein (12 kDa, Protein from Porcine deltacoronavirus)
- 46e6 antibody heavy chain (23 kDa, Protein from Homo sapiens)
- Pdcov spike s1b domain in complex with the 67b12 and 46e6 antibody fab fragments (105 kDa, Complex from Homo sapiens)
- 67b12 antibody heavy chain (22 kDa, Protein from Homo sapiens)
Du W, Janssens R, Mykytyn AZ, Li W, Drabek D, van Haperen R, Chatziandreou M, Rissmann M, van der Lee J, van Dortmondt M, Martin IS, van Kuppeveld FJM, Hurdiss DL, Haagmans BL, Grosveld F, Bosch BJ
Front Immunol (2023) 14 pp. 1111385-1111385 [ Pubmed: 36895554 DOI: doi:10.3389/fimmu.2023.1111385 ]
Du W, Janssens R, Mykytyn AZ, Li W, Drabek D, van Haperen R, Chatziandreou M, Rissmann M, van der Lee J, van Dortmondt M, Martin IS, van Kuppeveld FJM, Hurdiss DL, Haagmans BL, Grosveld F, Bosch BJ
Front Immunol (2023) 14 pp. 1111385-1111385 [ Pubmed: 36895554 DOI: doi:10.3389/fimmu.2023.1111385 ]
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8c8p
Q-score: 0.22
Du W, Janssens R, Mykytyn AZ, Li W, Drabek D, van Haperen R, Chatziandreou M, Rissmann M, van der Lee J, van Dortmondt M, Martin IS, van Kuppeveld FJM, Hurdiss DL, Haagmans BL, Grosveld F, Bosch BJ
Front Immunol (2023) 14 pp. 1111385-1111385 [ Pubmed: 36895554 DOI: doi:10.3389/fimmu.2023.1111385 ]
- Heavy-chain-only antibody 10d12 (41 kDa, Protein from Mus musculus)
- Sars-cov-2 spike glycoprotein in complex with the 10d12 heavy-chain-only antibody (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,sars-cov-2 spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7r40
Q-score: 0.333
Du W, Hurdiss DL, Drabek D, Mykytyn AZ, Kaiser FK, Gonzalez-Hernandez M, Munoz-Santos D, Lamers MM, van Haperen R, Li W, Drulyte I, Wang C, Sola I, Armando F, Beythien G, Ciurkiewicz M, Baumgartner W, Guilfoyle K, Smits T, van der Lee J, van Kuppeveld FJM, van Amerongen G, Haagmans BL, Enjuanes L, Osterhaus ADME, Grosveld F, Bosch BJ
Sci Immunol (2022) 7 pp. eabp9312-eabp9312 [ DOI: doi:10.1126/sciimmunol.abp9312 Pubmed: 35471062 ]
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike glycoprotein in complex with the 87g7 antibody fab fragment (500 kDa, Complex)
- 87g7 light chain variable region (23 kDa, Protein from Homo sapiens)
- 87g7 heavy chain variable region (23 kDa, Protein from Homo sapiens)
- 87g7 antibody fab fragment (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Du W, Hurdiss DL, Drabek D, Mykytyn AZ, Kaiser FK, Gonzalez-Hernandez M, Munoz-Santos D, Lamers MM, van Haperen R, Li W, Drulyte I, Wang C, Sola I, Armando F, Beythien G, Ciurkiewicz M, Baumgartner W, Guilfoyle K, Smits T, van der Lee J, van Kuppeveld FJM, van Amerongen G, Haagmans BL, Enjuanes L, Osterhaus ADME, Grosveld F, Bosch BJ
Sci Immunol (2022) 7 pp. eabp9312-eabp9312 [ DOI: doi:10.1126/sciimmunol.abp9312 Pubmed: 35471062 ]
- Sars-cov-2 spike glycoprotein in complex with the 87g7 antibody fab fragment (500 kDa, Complex)
- 87g7 heavy chain variable domain (Protein from Homo sapiens)
- Fab (Complex from Homo sapiens)
- Sars-cov-2 spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- 87g7 light chain variable domain (Protein from Homo sapiens)
- Sars-cov-2 spike protein (Protein from Severe acute respiratory syndrome coronavirus 2)