HIV-1 JR-FL NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5902
Guenaga J, Alirezaei M, Feng Y, Alameh MG, Lee WH, Baboo S, Cluff J, Wilson R, Bale S, Ozorowski G, Lin P, Tam Y, Diedrich JK, Yates 3rd JR, Paulson JC, Ward AB, Weissman D, Wyatt RT
Front Immunol (2024) 15 pp. 1426232-1426232 [ Pubmed: 39119336 DOI: doi:10.3389/fimmu.2024.1426232 ]
HIV-1 JR-FL NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5756
Guenaga J, Alirezaei M, Feng Y, Alameh MG, Lee WH, Baboo S, Cluff J, Wilson R, Bale S, Ozorowski G, Lin P, Tam Y, Diedrich JK, Yates 3rd JR, Paulson JC, Ward AB, Weissman D, Wyatt RT
Front Immunol (2024) 15 pp. 1426232-1426232 [ Pubmed: 39119336 DOI: doi:10.3389/fimmu.2024.1426232 ]
HIV-1 1086c NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5403
Guenaga J, Alirezaei M, Feng Y, Alameh MG, Lee WH, Baboo S, Cluff J, Wilson R, Bale S, Ozorowski G, Lin P, Tam Y, Diedrich JK, Yates 3rd JR, Paulson JC, Ward AB, Weissman D, Wyatt RT
Front Immunol (2024) 15 pp. 1426232-1426232 [ DOI: doi:10.3389/fimmu.2024.1426232 Pubmed: 39119336 ]
HIV-1 1086c NFL.664 soluble trimer in complex with polyclonal Fab from rabbit U5919
Guenaga J, Alirezaei M, Feng Y, Alameh MG, Lee WH, Baboo S, Cluff J, Wilson R, Bale S, Ozorowski G, Lin P, Tam Y, Diedrich JK, Yates 3rd JR, Paulson JC, Ward AB, Weissman D, Wyatt RT
Front Immunol (2024) 15 pp. 1426232-1426232 [ Pubmed: 39119336 DOI: doi:10.3389/fimmu.2024.1426232 ]
HIV Env BG505 NFL TD+ in complex with antibody E70 fragment antigen binding
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 6p62
Q-score: 0.453
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
- Hiv-1 env bg505 nfl td+ in complex with rabbit monoclonal antibody e70 fragment antigen binding (570 kDa, Complex from Human immunodeficiency virus 1)
- Rabbit monoclonal antibody e70 heavy chain fragment antigen binding (23 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit monoclonal antibody e70 kappa chain (22 kDa, Protein from Oryctolagus cuniculus)
- Hiv-1 env bg505 nfl td+ (74 kDa, Protein from Human immunodeficiency virus 1)
HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding
Resolution: 3.94 Å
EM Method: Single-particle
Fitted PDBs: 6p65
Q-score: 0.388
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
- Rabbit antibody 1c2 heavy chain fragment antigen binding (27 kDa, Protein from Oryctolagus cuniculus)
- Rabbit antibody 1c2 kappa chain (25 kDa, Protein from Oryctolagus cuniculus)
- Hiv env 16055 nfl td 2cc+ (75 kDa, Protein from Human immunodeficiency virus 1)
- Hiv env 16055 nfl td 2cc+ in complex with antibody 1c2 fragment antigen binding (570 kDa, Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
- Hiv-1 env bg505 nfl cc+ trimer in complex with rabbit antibody e70 fragment antigen binding (570 kDa, Complex)
- Rabbit antibody e70 fragment antigen binding kappa chain (Protein from Oryctolagus cuniculus)
- Rabbit antibody e70 fragment antigen binding heavy chain (Protein from Oryctolagus cuniculus)
- Hiv-1 env bg505 nfl cc+ trimer (Protein from Human immunodeficiency virus 1)
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vazquez Bernat N, Liban T, Louder M, McKee K, Bailer RT, Movsesyan A, Doria-Rose NA, Pancera M, Karlsson Hedestam GB, Zwick MB, Crispin M, Mascola JR, Ward AB, Wyatt RT
Immunity (2019) 51 pp. 915-929.e7 [ Pubmed: 31732167 DOI: doi:10.1016/j.immuni.2019.10.008 ]
- Hiv-1 env 16055 nfl td 2cc+ trimer in complex with rabbit antibody 1c2 fragment antigen binding (570 kDa, Complex)
- Rabbit antibody 1c2 fragment antigen binding kappa chain (Protein from Oryctolagus cuniculus)
- Hiv-1 env 16055 nfl td 2cc+ trimer (Protein from Human immunodeficiency virus 1)
- Rabbit antibody 1c2 fragment antigen binding heavy chain (Protein from Oryctolagus cuniculus)
Cao L, Pauthner M, Andrabi R, Rantalainen K, Berndsen Z, Diedrich JK, Menis S, Sok D, Bastidas R, Park SR, Delahunty CM, He L, Guenaga J, Wyatt RT, Schief WR, Ward AB, Burton DR, Paulson JC
Nat Commun (2018) 9 pp. 3693-3693 [ DOI: doi:10.1038/s41467-018-06121-4 Pubmed: 30209313 ]
- Hiv-1 envelope glycoprotein clone b41_delct (Protein from Human immunodeficiency virus 1)
- Hiv-1 envelope glycoprotein clone b41dct in complex with the broadly neutralizing antibody fab pgt151 (Complex from Human immunodeficiency virus 1)
- Immunoglobulin g pgt151, light chain (Protein)
- Immunoglobulin g pgt151 fab, heavy chain (Protein from Homo sapiens)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6mar
Q-score: 0.361
Cao L, Pauthner M, Andrabi R, Rantalainen K, Berndsen Z, Diedrich JK, Menis S, Sok D, Bastidas R, Park SR, Delahunty CM, He L, Guenaga J, Wyatt RT, Schief WR, Ward AB, Yates JR, Burton DR, Paulson JC
Nat Commun (2018) 9 pp. 3693-3693 [ DOI: doi:10.1038/s41467-018-06121-4 Pubmed: 30209313 ]
- Immunoglobulin g pgt151 fab, heavy chain (26 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp160 (24 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (55 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 envelope glycoprotein clone bg505 delct n332t in complex with broadly neutralizing antibody fab pgt151 (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin g pgt151, light chain (24 kDa, Protein from Homo sapiens)