ASFV RNAP M1249L C-tail occupied complex4 (MCOC4)
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Magnesium ion (24 Da, Ligand)
- D339l (38 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- M1249l (144 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- C147l (16 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (140 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex4 (mcoc4) (Complex from African swine fever virus)
- Dna-directed rna polymerase subunit (163 kDa, Protein from African swine fever virus)
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase subunit beta (138 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- D339l (9 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
- Dna (5'-d(p*tp*tp*cp*gp*cp*cp*gp*tp*tp*gp*cp*gp*tp*ap*tp*tp*tp*gp*tp*gp*tp*ap*g)-3') (7 kDa, DNA from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Rna polymerase subunit 6 (12 kDa, Protein from African swine fever virus)
- Dna (5'-d(p*cp*gp*cp*ap*ap*cp*gp*gp*cp*gp*a)-3') (3 kDa, DNA from African swine fever virus)
- Asfv rnap elongation complex (Complex from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Rna (5'-r(p*cp*up*ap*cp*ap*cp*ap*ap*a)-3') (2 kDa, RNA from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex1 (MCOC1)
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8xx5
Q-score: 0.607
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ Pubmed: 39779680 DOI: doi:10.1038/s41467-024-55683-z ]
- Magnesium ion (24 Da, Ligand)
- C122r (11 kDa, Protein from African swine fever virus)
- C147l (15 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- D339l (38 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- Asfv rnap m1249l c-tail occupied complex1 (mcoc1) (Complex from African swine fever virus)
- M1249l (137 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xxp
Q-score: 0.591
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ Pubmed: 39779680 DOI: doi:10.1038/s41467-024-55683-z ]
- Magnesium ion (24 Da, Ligand)
- C122r (11 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
- C147l (11 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- D339l (16 kDa, Protein from African swine fever virus)
- Asfv rnap core complex (Complex from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex2 (MCOC2)
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ DOI: doi:10.1038/s41467-024-55683-z Pubmed: 39779680 ]
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- M1249l (135 kDa, Protein from African swine fever virus)
- D339l (38 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex2 (mcoc2) (Complex from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- C147l (15 kDa, Protein from African swine fever virus)
- C122r (11 kDa, Protein from African swine fever virus)
ASFV RNAP M1249L C-tail occupied complex3 (MCOC3)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8xy6
Q-score: 0.519
Zhu G, Xi F, Zeng W, Zhao Y, Cao W, Liu C, Yang F, Ru Y, Xiao S, Zhang S, Liu H, Tian H, Yang F, Lu B, Sun S, Song H, Sun B, Zhao X, Tang L, Li K, He J, Guo J, Zhu Y, Zhu Z, Sun F, Zheng H
Nat Commun (2025) 16 pp. 501-501 [ Pubmed: 39779680 DOI: doi:10.1038/s41467-024-55683-z ]
- M1249l (66 kDa, Protein from African swine fever virus)
- C147l (14 kDa, Protein from African swine fever virus)
- D339l (16 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit beta (139 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb10 homolog (9 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb5 homolog (23 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase rpb3-11 homolog (41 kDa, Protein from African swine fever virus)
- Dna-directed rna polymerase subunit (162 kDa, Protein from African swine fever virus)
- Asfv rnap m1249l c-tail occupied complex3 (mcoc3) (Complex from African swine fever virus)
- Magnesium ion (24 Da, Ligand)
- C122r (11 kDa, Protein from African swine fever virus)
- Zinc ion (65 Da, Ligand)
Cryo-EM of helical fibers formed by two peptides Pyn-K6 and Pyn-(EY)3
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9d70
Q-score: 0.39
Qiao Y, Zia A, Wu G, Liu Z, Guo J, Chu M, He H, Wang F, Xu B
J Am Chem Soc (2025) [ Pubmed: 39808585 DOI: doi:10.1021/jacs.4c12150 ]
- Pyr-k6 (1 kDa, Protein from synthetic construct)
- Pyr-ey3 (1 kDa, Protein from synthetic construct)
- Pyn-k6 + pyn-ey3 fiber (Complex from synthetic construct)
- (pyren-1-yl)acetic acid (260 Da, Ligand)
Structure of the HER2 (S310F) - pertuzumab (T30S/D31A) complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9l1s
Q-score: 0.459
Bai X, Xu L, Wang Z, Zhuang X, Ning J, Sun Y, Wang H, Guo Y, Xu Y, Guo J, Chen S, Pan L
To Be Published
- Pertuzumab fab heavy chain (24 kDa, Protein from Homo sapiens)
- Pertuzumab fab light chain (23 kDa, Protein from Homo sapiens)
- Receptor tyrosine-protein kinase erbb-2 (70 kDa, Protein from Homo sapiens)
- Her2 (s310f) - pertuzumab (t30s/d31a) complex (Complex from Homo sapiens)
heterodimer of mGlu2 and mGlu4 bound with mGlu2 agonist LY379268
Resolution: 5.95 Å
EM Method: Single-particle
Fitted PDBs: 8wgc
Q-score: 0.215
Huang W, Jin N, Guo J, Shen C, Xu C, Xi K, Bonhomme L, Quast RB, Shen DD, Qin J, Liu YR, Song Y, Gao Y, Margeat E, Rondard P, Pin JP, Zhang Y, Liu J
Nat Commun (2024) 15 pp. 10345-10345 [ Pubmed: 39609406 DOI: doi:10.1038/s41467-024-54744-7 ]
- Heterodimer of mglu2 and mglu4 bound with mglu2 agonist ly379268 (Complex from Homo sapiens)
- (1r,4r,5s,6r)-4-azanyl-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid (187 Da, Ligand)
- Metabotropic glutamate receptor 4 (98 kDa, Protein from Homo sapiens)
- Metabotropic glutamate receptor 2 (93 kDa, Protein from Homo sapiens)
Cryo-EM structure of mGlu2-mGlu4 bound mGlu2 agonist LY379268