Cryo-EM structure of the SS-14-bound human SSTR2-Gi1 complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7wic
Q-score: 0.509
Chen LN, Wang WW, Dong YJ, Shen DD, Guo J, Yu X, Qin J, Ji SY, Zhang H, Shen Q, He Q, Yang B, Zhang Y, Li Q, Mao C
Cell Res (2022) 32 pp. 785-788 [ DOI: doi:10.1038/s41422-022-00669-z Pubmed: 35578016 ]
- Cryo-em structure of the ss-14-bound sstr2-gi1 complex (180 kDa, Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- G protein (Complex from Homo sapiens)
- Somatostatin receptor type 2 (41 kDa, Protein from Homo sapiens)
- Somatostatin-14 (1 kDa, Protein from Homo sapiens)
- Somatostatin receptor type 2 (Complex from Homo sapiens)
- Antibody (Complex from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Single fab chain (svfv16) (28 kDa, Protein from synthetic construct)
Cryo-EM structure of the L-054,264-bound human SSTR2-Gi1 complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7wig
Q-score: 0.527
Chen LN, Wang WW, Dong YJ, Shen DD, Guo J, Yu X, Qin J, Ji SY, Zhang H, Shen Q, He Q, Yang B, Zhang Y, Li Q, Mao C
Cell Res (2022) 32 pp. 785-788 [ DOI: doi:10.1038/s41422-022-00669-z Pubmed: 35578016 ]
- ~{n}-[(2~{r})-1-[[(1~{r},3~{s})-3-(aminomethyl)cyclohexyl]methylamino]-3-(1~{h}-indol-3-yl)-1-oxidanylidene-propan-2-yl]spiro[indene-1,4'-piperidine]-1'-carboxamide (539 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- G protein (Complex from Homo sapiens)
- Somatostatin receptor type 2 (41 kDa, Protein from Homo sapiens)
- Somatostatin receptor type 2 (Complex from Homo sapiens)
- Cryo-em structure of the l-054,264-bound sstr2-gi1 complex (180 kDa, Complex)
- Antibody (Complex from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Single fab chain (svfv16) (28 kDa, Protein from synthetic construct)
Structure of Apo-hsTRPM2 channel
Resolution: 3.76 Å
EM Method: Single-particle
Fitted PDBs: 7vq1
Q-score: 0.383
Yu X, Xie Y, Zhang X, Ma C, Liu L, Zhen W, Xu L, Zhang J, Liang Y, Zhao L, Gao X, Yu P, Luo J, Jiang LH, Nie Y, Yang F, Guo J, Yang W
Cell Rep (2021) 37 pp. 110025-110025 [ Pubmed: 34788616 DOI: doi:10.1016/j.celrep.2021.110025 ]
- Trpm2 (Cell from Homo sapiens)
- Transient receptor potential cation channel subfamily m member 2 (171 kDa, Protein from Homo sapiens)
Structure of Apo-hsTRPM2 channel TM domain
Resolution: 3.68 Å
EM Method: Single-particle
Fitted PDBs: 7vq2
Q-score: 0.206
Yu X, Xie Y, Zhang X, Ma C, Liu L, Zhen W, Xu L, Zhang J, Liang Y, Zhao L, Gao X, Yu P, Luo J, Jiang LH, Nie Y, Yang F, Guo J, Yang W
Cell Rep (2021) 37 pp. 110025-110025 [ Pubmed: 34788616 DOI: doi:10.1016/j.celrep.2021.110025 ]
- Trpm2 (Cell from Homo sapiens)
- Transient receptor potential cation channel subfamily m member 2 (40 kDa, Protein from Homo sapiens)
Al-bound structure of the AtALMT1 mutant M60A
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7voj
Q-score: 0.504
Wang J, Yu X, Ding ZJ, Zhang X, Luo Y, Xu X, Xie Y, Li X, Yuan T, Zheng SJ, Yang W, Guo J
Cell Res (2022) 32 pp. 89-98 [ Pubmed: 34799726 DOI: doi:10.1038/s41422-021-00587-6 ]
- Acetic acid (60 Da, Ligand)
- Aluminum-activated malate transporter 1 (56 kDa, Protein from Arabidopsis thaliana)
- Al-bound protein sample of the atalmt1 mutant m60a (120 MDa, Complex from Arabidopsis thaliana)
- Aluminum ion (26 Da, Ligand)
The malate-bound AtALMT1 structure at pH 7.5 (ALMT1malate/pH7.5)
