Structure of the EVA71 strain 11316 capsid
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 6uh1
Q-score: 0.469
Martinez-Gualda B, Sun L, Marti-Mari O, Noppen S, Abdelnabi R, Bator CM, Quesada E, Delang L, Mirabelli C, Lee H, Schols D, Neyts J, Hafenstein S, Camarasa MJ, Gago F, San-Felix A
J Med Chem (2020) 63 pp. 349-368 [ Pubmed: 31809045 DOI: doi:10.1021/acs.jmedchem.9b01737 ]
- Vp1 (32 kDa, Protein from Enterovirus A71)
- Vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Vp4 (7 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Vp2 (27 kDa, Protein from Enterovirus A71)
EV-A71 strain 11316 complexed with MADAL compound 22
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 6uh6
Q-score: 0.441
Martinez-Gualda B, Sun L, Marti-Mari O, Noppen S, Abdelnabi R, Bator CM, Quesada E, Delang L, Mirabelli C, Lee H, Schols D, Neyts J, Hafenstein S, Camarasa MJ, Gago F, San-Felix A
J Med Chem (2020) 63 pp. 349-368 [ Pubmed: 31809045 DOI: doi:10.1021/acs.jmedchem.9b01737 ]
- Vp1 (32 kDa, Protein from Enterovirus A71)
- Vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Vp4 (7 kDa, Protein from Enterovirus A71)
- Vp2 (26 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
EV-A71 strain 11316 complexed with MADAL compound 30
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 6uh7
Q-score: 0.468
Martinez-Gualda B, Sun L, Marti-Mari O, Noppen S, Abdelnabi R, Bator CM, Quesada E, Delang L, Mirabelli C, Lee H, Schols D, Neyts J, Hafenstein S, Camarasa MJ, Gago F, San-Felix A
J Med Chem (2020) 63 pp. 349-368 [ Pubmed: 31809045 DOI: doi:10.1021/acs.jmedchem.9b01737 ]
- Vp1 (32 kDa, Protein from Enterovirus A71)
- Vp3 (26 kDa, Protein from Enterovirus A71)
- Enterovirus a71 (Virus from Enterovirus A71)
- Vp4 (7 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Vp2 (27 kDa, Protein from Enterovirus A71)
Structure of the EVA71 strain 11316 capsid
Sun L, Lee H, Thibaut HJ, Lanko K, Rivero-Buceta E, Bator C, Martinez-Gualda B, Dallmeier K, Delang L, Leyssen P, Gago F, San-Felix A, Hafenstein S, Mirabelli C, Neyts J
PLoS Pathog (2019) 15 pp. e1007760-e1007760 [ DOI: doi:10.1371/journal.ppat.1007760 Pubmed: 31071193 ]
- Vp3 (26 kDa, Protein from Enterovirus A71)
- Sphingosine (299 Da, Ligand)
- Enterovirus a71 (Virus from Enterovirus A71)
- Vp1 (32 kDa, Protein from Enterovirus A71)
- Vp4 (7 kDa, Protein from Enterovirus A71)
- Vp2 (26 kDa, Protein from Enterovirus A71)
EV-A71 strain 11316 complexed with tryptophan dendrimer MADAL_0385
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 6diz
Q-score: 0.509
Sun L, Lee H, Thibaut HJ, Lanko K, Rivero-Buceta E, Bator C, Martinez-Gualda B, Dallmeier K, Delang L, Leyssen P, Gago F, San-Felix A, Hafenstein S, Mirabelli C, Neyts J
PLoS Pathog (2019) 15 pp. e1007760-e1007760 [ Pubmed: 31071193 DOI: doi:10.1371/journal.ppat.1007760 ]
- Sphingosine (299 Da, Ligand)
- Enterovirus a71 (Virus from Enterovirus A71)
- Vp2 (26 kDa, Protein from Enterovirus A71)
- Vp4 (8 kDa, Protein from Enterovirus A71)
- Vp1 (32 kDa, Protein from Enterovirus A71)
- Vp3 (26 kDa, Protein from Enterovirus A71)
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6bsp
Q-score: 0.193
Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S
Viruses (2017) 9 [ DOI: doi:10.3390/v9120374 Pubmed: 29211035 ]
- Antibody u4 (Complex from Mus musculus)
- Major capsid protein l1 (52 kDa, Protein from Human papillomavirus type 16)
- U4 light chain (12 kDa, Protein from Mus musculus)
- U4 heavy chain (12 kDa, Protein from Mus musculus)
- Human papillomavirus type 16 / antibody complex (Complex)
- Human papillomavirus type 16 (Virus from Human papillomavirus type 16)
Near-atomic resolution cryo-EM reconstruction of HPV16 complexed with Fab V5
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6bt3
Q-score: 0.294
Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S
Viruses (2017) 9 [ DOI: doi:10.3390/v9120374 Pubmed: 29211035 ]
Electron cryo-microscopy of Human Papillomavirus
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5keq
Q-score: 0.287
Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S
Structure (2017) 25 pp. 253-263 [ DOI: doi:10.1016/j.str.2016.12.001 Pubmed: 28065506 ]
Electron cryo-microscopy of Human Papillomavirus
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5kep
Q-score: 0.333
Guan J, Bywaters SM, Brendle SA, Ashley RE, Makhov AM, Conway JF, Christensen ND, Hafenstein S
Structure (2017) 25 pp. 253-263 [ Pubmed: 28065506 DOI: doi:10.1016/j.str.2016.12.001 ]
- Human papillomavirus (29 MDa, Sample)
- Human papillomavirus 16 (29 MDa, Virus from Human papillomavirus 16)
Deformed Wing Virus Assembly Intermediate Procapsid
Organtini LJ, Shingler KL, Ashley RE, Capaldi EA, Durrani K, Dryden KA, Makhov AM, Conway JF, Pizzorno MC, Hafenstein S
J Virol (2017) 91 [ Pubmed: 27852845 DOI: doi:10.1128/JVI.01795-16 ]