Plasmodium falciparum 20S proteasome bound to an inhibitor
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8w2f
Q-score: 0.576
Lawong A, Gahalawat S, Ray S, Ho N, Han Y, Ward KE, Deng X, Chen Z, Kumar A, Xing C, Hosangadi V, Fairhurst KJ, Tashiro K, Liszczak G, Shackleford DM, Katneni K, Chen G, Saunders J, Crighton E, Casas A, Robinson JJ, Imlay LS, Zhang X, Lemoff A, Zhao Z, Angulo-Barturen I, Jimenez-Diaz MB, Wittlin S, Campbell SF, Fidock DA, Laleu B, Charman SA, Ready JM, Phillips MA
Cell Chem Biol (2024) 31 pp. 1503- [ DOI: doi:10.1016/j.chembiol.2024.07.001 Pubmed: 39084225 ]
- Proteasome subunit alpha type (27 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (33 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome endopeptidase complex (26 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (27 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (24 kDa, Protein from Plasmodium falciparum 3D7)
- (3s)-1-[(2-fluoroethoxy)acetyl]-n-{[(4p)-4-(6-methylpyridin-3-yl)-1,3-thiazol-2-yl]methyl}piperidine-3-carboxamide (420 Da, Ligand)
- Proteasome subunit alpha type (28 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (25 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (22 kDa, Protein from Plasmodium falciparum 3D7)
- Plasmodium falciparum 20s proteasome bound with an inhibitor (750 kDa, Complex from Plasmodium falciparum 3D7)
- Proteasome endopeptidase complex (29 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit alpha type-3, putative (29 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit alpha type (27 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome endopeptidase complex (28 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta type-6, putative (29 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta type (23 kDa, Protein from Plasmodium falciparum 3D7)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8hj1
Q-score: 0.445
Lin X, Chen B, Wu Y, Han Y, Qi A, Wang J, Yang Z, Wei X, Zhao T, Wu L, Xie X, Sun J, Zheng J, Zhao S, Xu F
Nat Commun (2023) 14 pp. 216-216 [ DOI: doi:10.1038/s41467-023-35882-w Pubmed: 36639690 ]
- Gpr21(wt) with gs complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (16 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (10 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 21 (39 kDa, Protein from Homo sapiens)
Human VPS29/VPS35L Complex (Locally refined map)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8sym
Q-score: 0.446
Human VPS35L/VPS29/VPS26C Complex
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8syn
Q-score: 0.38
Boesch DJ, Singla A, Han Y, Kramer DA, Liu Q, Suzuki K, Juneja P, Zhao X, Long X, Medlyn MJ, Billadeau DD, Chen Z, Chen B, Burstein E
Nat Struct Mol Biol (2024) 31 pp. 910-924 [ DOI: doi:10.1038/s41594-023-01184-4 Pubmed: 38062209 ]
- Trimeric complex of full-length vps35l/vps29/vps26c (Complex from Homo sapiens)
- Vacuolar protein sorting-associated protein 29 (23 kDa, Protein from Homo sapiens)
- Vps35 endosomal protein-sorting factor-like (109 kDa, Protein from Homo sapiens)
- Vacuolar protein sorting-associated protein 26c (33 kDa, Protein from Homo sapiens)
Human Retriever VPS35L/VPS29/VPS26C Complex (Composite Map)
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8syo
Q-score: 0.429
Boesch DJ, Singla A, Han Y, Kramer DA, Liu Q, Suzuki K, Juneja P, Zhao X, Long X, Medlyn MJ, Billadeau DD, Chen Z, Chen B, Burstein E
Nat Struct Mol Biol (2024) 31 pp. 910-924 [ DOI: doi:10.1038/s41594-023-01184-4 Pubmed: 38062209 ]
- Trimeric complex of full-length vps35l/vps29/vps26c (Complex from Homo sapiens)
- Vacuolar protein sorting-associated protein 29 (23 kDa, Protein from Homo sapiens)
- Vps35 endosomal protein-sorting factor-like (109 kDa, Protein from Homo sapiens)
- Vacuolar protein sorting-associated protein 26c (33 kDa, Protein from Homo sapiens)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8iss
Q-score: 0.497
Yuan L, Han Y, Zhao J, Zhang Y, Sun Y
Nat Commun (2023) 14 pp. 6071-6071 [ DOI: doi:10.1038/s41467-023-41845-y Pubmed: 37770519 ]
- Rna (88-mer) (28 kDa, RNA from Homo sapiens)
- Trna-splicing endonuclease subunit sen34 (33 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Trna-splicing endonuclease subunit sen54 (59 kDa, Protein from Homo sapiens)
- Trna-splicing endonuclease subunit sen15 (19 kDa, Protein from Homo sapiens)
- Trna-splicing endonuclease subunit sen2 (53 kDa, Protein from Homo sapiens)
- Human pre-trna splicing complex tsen with substrate rna (Complex from Homo sapiens)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8hix
Q-score: 0.489
Lin X, Chen B, Wu Y, Han Y, Qi A, Wang J, Yang Z, Wei X, Zhao T, Wu L, Xie X, Sun J, Zheng J, Zhao S, Xu F
Nat Commun (2023) 14 pp. 216-216 [ DOI: doi:10.1038/s41467-023-35882-w Pubmed: 36639690 ]
- Gpr21 and gs protein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Nb35 (16 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 21 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (10 kDa, Protein from Homo sapiens)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8hj2
Q-score: 0.425
Lin X, Chen B, Wu Y, Han Y, Qi A, Wang J, Yang Z, Wei X, Zhao T, Wu L, Xie X, Sun J, Zheng J, Zhao S, Xu F
Nat Commun (2023) 14 pp. 216-216 [ DOI: doi:10.1038/s41467-023-35882-w Pubmed: 36639690 ]
- Gpr21(wt) with g15 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Nb35 (16 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (10 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 21 (39 kDa, Protein from Homo sapiens)
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8hj0
Q-score: 0.466
Lin X, Chen B, Wu Y, Han Y, Qi A, Wang J, Yang Z, Wei X, Zhao T, Wu L, Xie X, Sun J, Zheng J, Zhao S, Xu F
Nat Commun (2023) 14 pp. 216-216 [ DOI: doi:10.1038/s41467-023-35882-w Pubmed: 36639690 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (28 kDa, Protein from Homo sapiens)
- Gpr21 m5 with g15 (Complex from Homo sapiens)
- Nb35 (16 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 21 (38 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (10 kDa, Protein from Homo sapiens)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 7chh
Q-score: -0.009
Du S, Cao Y, Zhu Q, Yu P, Qi F, Wang G, Du X, Bao L, Deng W, Zhu H, Liu J, Nie J, Zheng Y, Liang H, Liu R, Gong S, Xu H, Yisimayi A, Lv Q, Wang B, He R, Han Y, Zhao W, Bai Y, Qu Y, Gao X, Ji C, Wang Q, Gao N, Huang W, Wang Y, Xie XS, Su XD, Xiao J, Qin C
Cell (2020) 183 pp. 1013-1023.e13 [ Pubmed: 32970990 DOI: doi:10.1016/j.cell.2020.09.035 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of the sars-cov-2 s-6p with bd-368-2 fabs (Complex)
- Sars-cov-2 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Bd-368-2 fab light chain (23 kDa, Protein from Homo sapiens)
- Bd-368-2 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Bd-368-2 fabs (Complex from Homo sapiens)