Plasmodium falciparum 20S proteasome bound to an inhibitor
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8w2f
Q-score: 0.576
Lawong A, Gahalawat S, Ray S, Ho N, Han Y, Ward KE, Deng X, Chen Z, Kumar A, Xing C, Hosangadi V, Fairhurst KJ, Tashiro K, Liszczak G, Shackleford DM, Katneni K, Chen G, Saunders J, Crighton E, Casas A, Robinson JJ, Imlay LS, Zhang X, Lemoff A, Zhao Z, Angulo-Barturen I, Jimenez-Diaz MB, Wittlin S, Campbell SF, Fidock DA, Laleu B, Charman SA, Ready JM, Phillips MA
Cell Chem Biol (2024) 31 pp. 1503- [ Pubmed: 39084225 DOI: doi:10.1016/j.chembiol.2024.07.001 ]
- Proteasome endopeptidase complex (26 kDa, Protein from Plasmodium falciparum 3D7)
- Plasmodium falciparum 20s proteasome bound with an inhibitor (750 kDa, Complex from Plasmodium falciparum 3D7)
- Proteasome endopeptidase complex (28 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta type (23 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit alpha type (27 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit alpha type (28 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (33 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (25 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (27 kDa, Protein from Plasmodium falciparum 3D7)
- (3s)-1-[(2-fluoroethoxy)acetyl]-n-{[(4p)-4-(6-methylpyridin-3-yl)-1,3-thiazol-2-yl]methyl}piperidine-3-carboxamide (420 Da, Ligand)
- Proteasome subunit alpha type-3, putative (29 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta type-6, putative (29 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (22 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit alpha type (27 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome endopeptidase complex (29 kDa, Protein from Plasmodium falciparum 3D7)
- Proteasome subunit beta (24 kDa, Protein from Plasmodium falciparum 3D7)
Human VPS29/VPS35L Complex (Locally refined map)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8sym
Q-score: 0.446
Human VPS35L/VPS29/VPS26C Complex
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8syn
Q-score: 0.38
Boesch DJ, Singla A, Han Y, Kramer DA, Liu Q, Suzuki K, Juneja P, Zhao X, Long X, Medlyn MJ, Billadeau DD, Chen Z, Chen B, Burstein E
Nat Struct Mol Biol (2024) 31 pp. 910-924 [ Pubmed: 38062209 DOI: doi:10.1038/s41594-023-01184-4 ]
- Vacuolar protein sorting-associated protein 26c (33 kDa, Protein from Homo sapiens)
- Trimeric complex of full-length vps35l/vps29/vps26c (Complex from Homo sapiens)
- Vps35 endosomal protein-sorting factor-like (109 kDa, Protein from Homo sapiens)
- Vacuolar protein sorting-associated protein 29 (23 kDa, Protein from Homo sapiens)
Human Retriever VPS35L/VPS29/VPS26C Complex (Composite Map)
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8syo
Q-score: 0.429
Boesch DJ, Singla A, Han Y, Kramer DA, Liu Q, Suzuki K, Juneja P, Zhao X, Long X, Medlyn MJ, Billadeau DD, Chen Z, Chen B, Burstein E
Nat Struct Mol Biol (2024) 31 pp. 910-924 [ Pubmed: 38062209 DOI: doi:10.1038/s41594-023-01184-4 ]
- Vacuolar protein sorting-associated protein 26c (33 kDa, Protein from Homo sapiens)
- Trimeric complex of full-length vps35l/vps29/vps26c (Complex from Homo sapiens)
- Vps35 endosomal protein-sorting factor-like (109 kDa, Protein from Homo sapiens)
- Vacuolar protein sorting-associated protein 29 (23 kDa, Protein from Homo sapiens)