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primary_citation_author:"Hanssen E" AND xref_links:"go"
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Structure of Plasmodium falciparum 20S proteasome with bound bortezomib.

Release date: Sept. 22, 2021
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7lxt
Q-score: 0.498

Xie SC, Metcalfe RD, Mizutani H, Puhalovich T, Hanssen E, Morton CJ, Du Y, Dogovski C, Huang SC, Ciavarri J, Hales P, Griffin RJ, Cohen LH, Chuang BC, Wittlin S, Deni I, Yeo T, Ward KE, Barry DC, Liu B, Gillett DL, Crespo-Fernandez BF, Ottilie S, Mittal N, Churchyard A, Ferguson D, Aguiar ACC, Guido RVC, Baum J, Hanson KK, Winzeler EA, Gamo FJ, Fidock DA, Baud D, Parker MW, Brand S, Dick LR, Griffin MDW, Gould AE, Tilley L

PNAS (2021) 118 [ Pubmed: 34548400 DOI: doi:10.1073/pnas.2107213118 ]

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Structure of Plasmodium falciparum 20S proteasome with bound ML052.

Release date: Sept. 22, 2021
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7lxu
Q-score: 0.524

Xie SC, Metcalfe RD, Mizutani H, Puhalovich T, Hanssen E, Morton CJ, Du Y, Dogovski C, Huang SC, Ciavarri J, Hales P, Griffin RJ, Cohen LH, Chuang BC, Wittlin S, Deni I, Yeo T, Ward KE, Barry DC, Liu B, Gillett DL, Crespo-Fernandez BF, Ottilie S, Mittal N, Churchyard A, Ferguson D, Aguiar ACC, Guido RVC, Baum J, Hanson KK, Winzeler EA, Gamo FJ, Fidock DA, Baud D, Parker MW, Brand S, Dick LR, Griffin MDW, Gould AE, Tilley L

PNAS (2021) 118 [ Pubmed: 34548400 DOI: doi:10.1073/pnas.2107213118 ]

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Structure of human 20S proteasome with bound ML052.

Release date: Sept. 22, 2021
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7lxv
Q-score: 0.496

Xie SC, Metcalfe RD, Mizutani H, Puhalovich T, Hanssen E, Morton CJ, Du Y, Dogovski C, Huang SC, Ciavarri J, Hales P, Griffin RJ, Cohen LH, Chuang BC, Wittlin S, Deni I, Yeo T, Ward KE, Barry DC, Liu B, Gillett DL, Crespo-Fernandez BF, Ottilie S, Mittal N, Churchyard A, Ferguson D, Aguiar ACC, Guido RVC, Baum J, Hanson KK, Winzeler EA, Gamo FJ, Fidock DA, Baud D, Parker MW, Brand S, Dick LR, Griffin MDW, Gould AE, Tilley L

PNAS (2021) 118 [ Pubmed: 34548400 DOI: doi:10.1073/pnas.2107213118 ]

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The structure of the Plasmodium falciparum 20S proteasome in complex with two PA28 activators.

Release date: Aug. 7, 2019
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6muv
Q-score: 0.397

Xie SC, Metcalfe RD, Hanssen E, Yang T, Gillett DL, Leis AP, Morton CJ, Kuiper MJ, Parker MW, Spillman NJ, Wong W, Tsu C, Dick LR, Griffin MDW, Tilley L

Nat Microbiol (2019) 4 pp. 1990-2000 [ Pubmed: 31384003 DOI: doi:10.1038/s41564-019-0524-4 ]

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The structure of the Plasmodium falciparum 20S proteasome.

Release date: Aug. 7, 2019
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6muw
Q-score: 0.461

Xie SC, Metcalfe RD, Hanssen E, Yang T, Gillett DL, Leis AP, Morton CJ, Kuiper MJ, Parker MW, Spillman NJ, Wong W, Tsu C, Dick LR, Griffin MDW, Tilley L

Nat Microbiol (2019) 4 pp. 1990-2000 [ Pubmed: 31384003 DOI: doi:10.1038/s41564-019-0524-4 ]

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