Structure of the AcMNPV baculovirus VP39 nucleocapsid (C14 helical reconstruction)
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F
Sci Adv (2024) 10 pp. eado2631-eado2631 [ Pubmed: 39693434 DOI: doi:10.1126/sciadv.ado2631 ]
- Major nucleocapsid protein vp39 of autographa californica multiple nucleopolyhedrovirus (Protein from Autographa californica multiple nucleopolyhedrovirus)
- Autographa californica multiple nucleopolyhedrovirus (126 MDa, Virus from Autographa californica multiple nucleopolyhedrovirus)
- C14 reconstruction of the helical portion of the nucleocapsid formed by dimers of vp39 (Complex from Autographa californica multiple nucleopolyhedrovirus)
Structure of the baculovirus major nucleocapsid protein VP39 (localised reconstruction)
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8vwh
Q-score: 0.491
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F
To Be Published
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco M, Krupovic M, Coulibaly F
To Be Published
The base complex of the AcMNPV baculovirus nucleocapsid (Class 1, localised reconstruction)
Resolution: 4.71 Å
EM Method: Single-particle
Fitted PDBs: 8vwi
Q-score: 0.252
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F
To Be Published
- Capsid-associated protein vp80 (79 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Protein ac142 (55 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Protein c42 (41 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Occlusion-derived virus envelope protein e27 (33 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Major capsid protein (38 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- 38k (ac98) protein in p143-lef5 intergenic region (38 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Protein ac109 (44 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Autographa californica multiple nucleopolyhedrovirus (Virus from Autographa californica multiple nucleopolyhedrovirus)
- Zinc ion (65 Da, Ligand)
The base complex of the AcMNPV baculovirus nucleocapsid (Class 2, localised reconstruction)
Resolution: 4.78 Å
EM Method: Single-particle
Fitted PDBs: 8vwj
Q-score: 0.243
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F
To Be Published
- Autographa californica multiple nucleopolyhedrovirus (Virus from Autographa californica multiple nucleopolyhedrovirus)
- 38k (ac98) (38 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Major capsid protein (38 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Zinc ion (65 Da, Ligand)
- Protein ac142 (55 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Protein ac109 (44 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Capsid-associated protein vp80 (79 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Occlusion-derived virus envelope protein e27 (33 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
- Protein c42 (41 kDa, Protein from Autographa californica multiple nucleopolyhedrovirus)
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F
To Be Published
Cryo-EM structure of murine Thrombopoietin receptor ectodomain in complex with Tpo
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8u18
Q-score: 0.394
Sarson-Lawrence KTG, Hardy JM, Iaria J, Stockwell D, Behrens K, Saiyed T, Tan C, Jebeli L, Scott NE, Dite TA, Nicola NA, Leis AP, Babon JJ, Kershaw NJ
Nat Commun (2024) 15 pp. 1135-1135 [ Pubmed: 38326297 DOI: doi:10.1038/s41467-024-45356-2 ]
- Alpha-d-mannopyranose (180 Da, Ligand)
- 2:1 complex of the mouse thrombopoietin receptor ectodomain and mouse thrombopoietin (131 kDa, Complex)
- Thrombopoietin receptor,gcn4 isoform 1 (56 kDa, Protein from Saccharomyces cerevisiae)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Mouse thrombopoietin (Complex from Mus musculus)
- Thrombopoietin (19 kDa, Protein from Mus musculus)
- Mouse thrombopoietin receptor ectodomain (Complex from Mus musculus)
Binjari virus (BinJV) complexed with pr-specific Fab 2A7
Newton ND, Hardy JM, Modhiran N, Hugo LE, Amarilla AA, Bibby S, Venugopal H, Harrison JJ, Traves RJ, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Sci Adv (2021) 7 [ Pubmed: 33990320 DOI: doi:10.1126/sciadv.abe4507 ]
- Binjari virus complexed with pr-specific fab 2a7 (22 MDa, Complex)
- 2a7 fab (50 kDa, Complex from Mus musculus)
- Binjari virus (22 MDa, Virus from Binjari virus)
The structure of an infectious immature flavivirus redefines viral architecture and maturation
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7l30
Q-score: 0.418
Newton ND, Hardy JM, Modhiran N, Hugo LE, Amarilla AA, Bibby S, Venugopal H, Harrison JJ, Traves RJ, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Sci Adv (2021) 7 [ Pubmed: 33990320 DOI: doi:10.1126/sciadv.abe4507 ]
- Envelope protein e (53 kDa, Protein from Binjari virus)
- Binjari virus (22 MDa, Virus from Binjari virus)
- Prm protein (18 kDa, Protein from Binjari virus)