Structure of the AcMNPV baculovirus VP39 nucleocapsid (C14 helical reconstruction)
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F
Sci Adv (2024) 10 pp. eado2631-eado2631 [ DOI: doi:10.1126/sciadv.ado2631 Pubmed: 39693434 ]
- Major nucleocapsid protein vp39 of autographa californica multiple nucleopolyhedrovirus (Protein from Autographa californica multiple nucleopolyhedrovirus)
- Autographa californica multiple nucleopolyhedrovirus (126 MDa, Virus from Autographa californica multiple nucleopolyhedrovirus)
- C14 reconstruction of the helical portion of the nucleocapsid formed by dimers of vp39 (Complex from Autographa californica multiple nucleopolyhedrovirus)
Structure of the baculovirus major nucleocapsid protein VP39 (localised reconstruction)
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8vwh
Q-score: 0.491
Johnstone BA, Hardy JM, Ha J, Butkovic A, Koszalka P, Accurso C, Venugopal H, de Marco A, Krupovic M, Coulibaly F
To Be Published
Binjari virus (BinJV) complexed with pr-specific Fab 2A7
Newton ND, Hardy JM, Modhiran N, Hugo LE, Amarilla AA, Bibby S, Venugopal H, Harrison JJ, Traves RJ, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Sci Adv (2021) 7 [ Pubmed: 33990320 DOI: doi:10.1126/sciadv.abe4507 ]
- Binjari virus (22 MDa, Virus from Binjari virus)
- Binjari virus complexed with pr-specific fab 2a7 (22 MDa, Complex)
- 2a7 fab (50 kDa, Complex from Mus musculus)
The structure of an infectious immature flavivirus redefines viral architecture and maturation
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 7l30
Q-score: 0.418
Newton ND, Hardy JM, Modhiran N, Hugo LE, Amarilla AA, Bibby S, Venugopal H, Harrison JJ, Traves RJ, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Sci Adv (2021) 7 [ Pubmed: 33990320 DOI: doi:10.1126/sciadv.abe4507 ]
- Envelope protein e (53 kDa, Protein from Binjari virus)
- Prm protein (18 kDa, Protein from Binjari virus)
- Binjari virus (22 MDa, Virus from Binjari virus)
Chimeric flavivirus between Binjari virus and Dengue virus serotype-2
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7kv8
Q-score: 0.701
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Envelope protein e (54 kDa, Protein from Dengue virus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M and e from dengue virus serotype-2 isolate et300 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Dengue virus 2)
- (2s,3r,4z)-3-hydroxy-2-[(9e)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate (643 Da, Ligand)
- Binjari virus (11 MDa, Virus from Binjari virus)
- Matrix protein m (8 kDa, Protein from Dengue virus 2)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Water (18 Da, Ligand)
Chimeric flavivirus between Binjari virus and West Nile (Kunjin) virus
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7kv9
Q-score: 0.588
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Matrix protein m (8 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope protein e (53 kDa, Protein from Kunjin virus)
- Binjari virus (11 MDa, Virus from Binjari virus)
- M and e from west nile virus isolate nsw2011 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Kunjin virus)
Structure of West Nile virus (Kunjin)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7kva
Q-score: 0.555
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- Kunjin virus (22 MDa, Virus from Kunjin virus)
- Matrix protein m (8 kDa, Protein from Kunjin virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope protein e (53 kDa, Protein from Kunjin virus)
Chimeric flavivirus between Binjari virus and Murray Valley encephalitis virus
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7kvb
Q-score: 0.48
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D
Nat Commun (2021) 12 pp. 3266-3266 [ Pubmed: 34075032 DOI: doi:10.1038/s41467-021-22773-1 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope protein e (53 kDa, Protein from Murray Valley encephalitis virus)
- Binjari virus (11 MDa, Virus from Binjari virus)
- Matrix protein m (8 kDa, Protein from Murray Valley encephalitis virus)
- M and e from murray valley encephalitis virus strain mve-1-51 form a complex that assembles into anti-parallel dimers, (m-e)2, in the t=3 icosahedral particle. (Complex from Murray Valley encephalitis virus)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6xgq
Q-score: 0.488
Hardy JM, Dunstan RA, Grinter R, Belousoff MJ, Wang J, Pickard D, Venugopal H, Dougan G, Lithgow T, Coulibaly F
Nat Commun (2020) 11 pp. 3748-3748 [ DOI: doi:10.1038/s41467-020-17505-w Pubmed: 32719311 ]
- Ysd1_16 (14 kDa, Protein from Bacteriophage sp.)
- Ysd1_17 (39 kDa, Protein from Bacteriophage sp.)
- Bacteriophage sp. (22 MDa, Virus from Bacteriophage sp.)
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 6xgr
Q-score: 0.493
Hardy JM, Dunstan RA, Grinter R, Belousoff MJ, Wang J, Pickard D, Venugopal H, Dougan G, Lithgow T, Coulibaly F
Nat Commun (2020) 11 pp. 3748-3748 [ DOI: doi:10.1038/s41467-020-17505-w Pubmed: 32719311 ]
- Bacteriophage sp. (56 MDa, Virus from Bacteriophage sp.)
- Ysd1_22 major tail protein (40 kDa, Protein from Bacteriophage sp.)