Rat TRPV2 WT bound to probenecid
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 9b3u
Q-score: 0.61
Rocereta JA, Sturhahn T, Pumroy RA, Fricke TC, Herzog C, Leffler A, Moiseenkova-Bell VY
To Be Published
- 1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (522 Da, Ligand)
- Homotetramer of rat trpv2 wt (Complex from Rattus norvegicus)
- 4-(dipropylsulfamoyl)benzoic acid (285 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
Rat TRPV2 WT in the presence of probenecid and 2-APB
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 9b3v
Q-score: 0.381
Rocereta JA, Sturhahn T, Pumroy RA, Fricke TC, Herzog C, Leffler A, Moiseenkova-Bell VY
To Be Published
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 9b3w
Q-score: 0.622
Rocereta JA, Sturhahn T, Pumroy RA, Fricke TC, Herzog C, Leffler A, Moiseenkova-Bell VY
To Be Published
Rat TRPV2 E724A/D725A bound to 2-APB
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9b3x
Q-score: 0.502
Rocereta JA, Sturhahn T, Pumroy RA, Fricke TC, Herzog C, Leffler A, Moiseenkova-Bell VY
To Be Published
- Homotetramer of rat trpv2 e724a/d725a mutant (Complex from Rattus norvegicus)
- 1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (522 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
- 2-aminoethyl diphenylborinate (225 Da, Ligand)
Rat TRPV2 E724A/D725A bound to probenecid
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9b3y
Q-score: 0.558
Rocereta JA, Sturhahn T, Pumroy RA, Fricke TC, Herzog C, Leffler A, Moiseenkova-Bell VY
To Be Published
- Homotetramer of rat trpv2 e724a/d725a mutant (Complex from Rattus norvegicus)
- 1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (522 Da, Ligand)
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
- 4-(dipropylsulfamoyl)benzoic acid (285 Da, Ligand)
Rat TRPV2 E724A/D725A bound to probenecid and 2-APB
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9b3z
Q-score: 0.519
Rocereta JA, Sturhahn T, Pumroy RA, Fricke TC, Herzog C, Leffler A, Moiseenkova-Bell VY
To Be Published
- Transient receptor potential cation channel subfamily v member 2 (86 kDa, Protein from Rattus norvegicus)
- 1,2-didecanoyl-sn-glycero-3-phosphoethanolamine (522 Da, Ligand)
- 4-(dipropylsulfamoyl)benzoic acid (285 Da, Ligand)
- Homotetramer of rat trpv2 e724a/d725a mutant (Complex from Rattus norvegicus)
- 2-aminoethyl diphenylborinate (225 Da, Ligand)
Apo rat TRPV2 in nanodiscs, state 1
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8ekp
Q-score: 0.599
Haug FM, Pumroy RA, Sridhar A, Pantke S, Dimek F, Fricke TC, Hage A, Herzog C, Echtermeyer FG, de la Roche J, Koh A, Kotecha A, Howard RJ, Lindahl E, Moiseenkova-Bell V, Leffler A
EMBO J (2024) 43 pp. 2264-2290 [ Pubmed: 38671253 DOI: doi:10.1038/s44318-024-00106-4 ]
Apo rat TRPV2 in nanodiscs, state 2
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ekq
Q-score: 0.625
Haug FM, Pumroy RA, Sridhar A, Pantke S, Dimek F, Fricke TC, Hage A, Herzog C, Echtermeyer FG, de la Roche J, Koh A, Kotecha A, Howard RJ, Lindahl E, Moiseenkova-Bell V, Leffler A
EMBO J (2024) 43 pp. 2264-2290 [ Pubmed: 38671253 DOI: doi:10.1038/s44318-024-00106-4 ]
Apo rat TRPV2 in nanodiscs, state 3
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8ekr
Q-score: 0.521
Haug FM, Pumroy RA, Sridhar A, Pantke S, Dimek F, Fricke TC, Hage A, Herzog C, Echtermeyer FG, de la Roche J, Koh A, Kotecha A, Howard RJ, Lindahl E, Moiseenkova-Bell V, Leffler A
EMBO J (2024) 43 pp. 2264-2290 [ Pubmed: 38671253 DOI: doi:10.1038/s44318-024-00106-4 ]
rat TRPV2 in nanodiscs in the presence of weak acid at pH 5
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8eks
Q-score: 0.54
Haug FM, Pumroy RA, Sridhar A, Pantke S, Dimek F, Fricke TC, Hage A, Herzog C, Echtermeyer FG, de la Roche J, Koh A, Kotecha A, Howard RJ, Lindahl E, Moiseenkova-Bell V, Leffler A
EMBO J (2024) 43 pp. 2264-2290 [ Pubmed: 38671253 DOI: doi:10.1038/s44318-024-00106-4 ]