Hybrid aspen cellulose synthase-8 bound to UDP
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8g27
Q-score: 0.46
Verma P, Kwansa AL, Ho R, Yingling YG, Zimmer J
bioRxiv (2023) [ Pubmed: 36798277 DOI: doi:10.1101/2023.02.07.527505 ]
Hybrid aspen cellulose synthase-8 bound to UDP-glucose
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8g2j
Q-score: 0.404
Verma P, Kwansa AL, Ho R, Yingling YG, Zimmer J
bioRxiv (2023) [ Pubmed: 36798277 DOI: doi:10.1101/2023.02.07.527505 ]
- Cellulose synthase (112 kDa, Protein from Populus tremula x P. tremuloides/Amanita muscaria mixed EST library)
- Magnesium ion (24 Da, Ligand)
- Uridine-5'-diphosphate-glucose (566 Da, Ligand)
- Homotrimeric cellulose synthase complex (Complex from Populus tremula x Populus tremuloides)
Chlorella virus hyaluronan synthase
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7sp6
Q-score: 0.454
Maloney FP, Kuklewicz J, Corey RA, Bi Y, Ho R, Mateusiak L, Pardon E, Steyaert J, Stansfeld PJ, Zimmer J
Nature (2022) 604 pp. 195-201 [ Pubmed: 35355017 DOI: doi:10.1038/s41586-022-04534-2 ]
- Hyaluronan synthase in nanodiscs in complex with two camelid nanobodies. (95 kDa, Complex from Paramecium bursaria Chlorella virus CZ-2)
- Nanobody 881 (15 kDa, Protein from Lama glama)
- Hyaluronan synthase (65 kDa, Protein from Paramecium bursaria Chlorella virus CZ-2)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nanobody 872 (14 kDa, Protein from Lama glama)
Chlorella virus hyaluronan synthase inhibited by UDP
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7sp7
Q-score: 0.475
Maloney FP, Kuklewicz J, Corey RA, Bi Y, Ho R, Mateusiak L, Pardon E, Steyaert J, Stansfeld PJ, Zimmer J
Nature (2022) 604 pp. 195-201 [ Pubmed: 35355017 DOI: doi:10.1038/s41586-022-04534-2 ]
- Uridine-5'-diphosphate (404 Da, Ligand)
- Nanobody 881 (15 kDa, Protein from Lama glama)
- Manganese (ii) ion (54 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Hyaluronan synthase (65 kDa, Protein from Paramecium bursaria Chlorella virus CZ-2)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Hyaluronan synthase in nanodiscs in complex with two camelid nanobodies (95 kDa, Complex from Paramecium bursaria Chlorella virus CZ-2)
- Nanobody 872 (14 kDa, Protein from Lama glama)
Chlorella virus Hyaluronan Synthase bound to UDP-GlcNAc
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7sp8
Q-score: 0.536
Maloney FP, Kuklewicz J, Corey RA, Bi Y, Ho R, Mateusiak L, Pardon E, Steyaert J, Stansfeld PJ, Zimmer J
Nature (2022) 604 pp. 195-201 [ Pubmed: 35355017 DOI: doi:10.1038/s41586-022-04534-2 ]
- Hyaluronan synthase in nanodiscs in complex with two camelid nanobodies. (95 kDa, Complex from Paramecium bursaria Chlorella virus CZ-2)
- Nanobody 881 (15 kDa, Protein from Lama glama)
- Hyaluronan synthase (65 kDa, Protein from Paramecium bursaria Chlorella virus CZ-2)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- Nanobody 872 (14 kDa, Protein from Lama glama)
- Uridine-diphosphate-n-acetylglucosamine (607 Da, Ligand)
Chlorella virus Hyaluronan Synthase in the GlcNAc-primed channel-closed state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7sp9
Q-score: 0.486
Maloney FP, Kuklewicz J, Corey RA, Bi Y, Ho R, Mateusiak L, Pardon E, Steyaert J, Stansfeld PJ, Zimmer J
Nature (2022) 604 pp. 195-201 [ Pubmed: 35355017 DOI: doi:10.1038/s41586-022-04534-2 ]
- Hyaluronan synthase in nanodiscs in complex with two camelid nanobodies. (95 kDa, Complex from Paramecium bursaria Chlorella virus CZ-2)
- Hyaluronan synthase (65 kDa, Protein from Paramecium bursaria Chlorella virus CZ-2)
- Nanobody 881 (15 kDa, Protein from Lama glama)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Nanobody 872 (14 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Chlorella virus Hyaluronan Synthase in the GlcNAc-primed, channel-open state
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7spa
Q-score: 0.472
Maloney FP, Kuklewicz J, Corey RA, Bi Y, Ho R, Mateusiak L, Pardon E, Steyaert J, Stansfeld PJ, Zimmer J
Nature (2022) 604 pp. 195-201 [ Pubmed: 35355017 DOI: doi:10.1038/s41586-022-04534-2 ]
- Hyaluronan synthase in nanodiscs in complex with two camelid nanobodies. (95 kDa, Complex from Paramecium bursaria Chlorella virus CZ-2)
- Hyaluronan synthase (65 kDa, Protein from Paramecium bursaria Chlorella virus CZ-2)
- Nanobody 881 (15 kDa, Protein from Lama glama)
- Cholesterol hemisuccinate (486 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nanobody 872 (14 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Bacterial cellulose synthase BcsB hexamer
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7l2z
Q-score: 0.449
Acheson JF, Ho R, Goularte NF, Cegelski L, Zimmer J
Nat Struct Mol Biol (2021) 28 pp. 310-318 [ Pubmed: 33712813 DOI: doi:10.1038/s41594-021-00569-7 ]
- Cyclic di-gmp-binding protein (84 kDa, Protein from Escherichia coli (strain K12))
- Bacterial cellulose synthase bcsb hexamer (481 kDa, Complex from Escherichia coli K-12)
Bacterial cellulose synthase BcsB with polyalanine BcsA model
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7lby
Q-score: 0.308
Acheson JF, Ho R, Goularte NF, Cegelski L, Zimmer J
Nat Struct Mol Biol (2021) 28 pp. 310-318 [ Pubmed: 33712813 DOI: doi:10.1038/s41594-021-00569-7 ]
Structure of homotrimeric poplar cellulose synthase isoform 8
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6wlb
Q-score: 0.438
Science (2020) 369 pp. 1089-1094 [ Pubmed: 32646917 DOI: doi:10.1126/science.abb2978 ]
- Cesa (110 MDa, Complex from Populus tremula x Populus tremuloides)
- Cellulose synthase (112 kDa, Protein from Populus tremula x Populus tremuloides)