SARS-CoV-2 Delta Spike in complex with FP-12A
Resolution: 3.62 Å
EM Method: Single-particle
Fitted PDBs: 8hhx
Q-score: 0.301
Huang KA, Chen X, Mohapatra A, Nguyen HTV, Schimanski L, Tan TK, Rijal P, Vester SK, Hills RA, Howarth M, Keeffe JR, Cohen AA, Kakutani LM, Wu YM, Shahed-Al-Mahmud M, Chou YC, Bjorkman PJ, Townsend AR, Ma C
Nat Commun (2023) 14 pp. 311-311 [ DOI: doi:10.1038/s41467-023-35949-8 Pubmed: 36658148 ]
- Complex of delta spike and fp-12a with two fabs bound to one spike in 3-rbd-up conformation (550 kDa, Complex)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 delta spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fp-12a (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fp-12a fab heavy chain (23 kDa, Protein from Homo sapiens)
- Fp-12a fab light chain (23 kDa, Protein from Homo sapiens)
SARS-CoV-2 Delta Spike in complex with IS-9A
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8hhy
Q-score: 0.313
Huang KA, Chen X, Mohapatra A, Nguyen HTV, Schimanski L, Tan TK, Rijal P, Vester SK, Hills RA, Howarth M, Keeffe JR, Cohen AA, Kakutani LM, Wu YM, Shahed-Al-Mahmud M, Chou YC, Bjorkman PJ, Townsend AR, Ma C
Nat Commun (2023) 14 pp. 311-311 [ DOI: doi:10.1038/s41467-023-35949-8 Pubmed: 36658148 ]
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Is-9a fab (Complex from Homo sapiens)
- Is-9a fab heavy chain (24 kDa, Protein from Homo sapiens)
- Complex of delta spike and is-9a with two fabs bound to one spike in 3-rbd-up conformation (550 kDa, Complex)
- Is-9a fab light chain (23 kDa, Protein from Homo sapiens)
SARS-CoV-2 Omicron BA.1 Spike in complex with IY-2A
Resolution: 4.28 Å
EM Method: Single-particle
Fitted PDBs: 8hhz
Q-score: 0.207
Huang KA, Chen X, Mohapatra A, Nguyen HTV, Schimanski L, Tan TK, Rijal P, Vester SK, Hills RA, Howarth M, Keeffe JR, Cohen AA, Kakutani LM, Wu YM, Shahed-Al-Mahmud M, Chou YC, Bjorkman PJ, Townsend AR, Ma C
Nat Commun (2023) 14 pp. 311-311 [ DOI: doi:10.1038/s41467-023-35949-8 Pubmed: 36658148 ]
- Spike glycoprotein (140 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 delta spike protein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Complex of delta spike and iy-2a with two fabs bound to one spike in 3-rbd-up conformation (550 kDa, Complex)
- Iy-2a fab heavy chain (23 kDa, Protein from Homo sapiens)
- Iy-2a fab light chain (23 kDa, Protein from Homo sapiens)
- Iy-2a (Complex from Homo sapiens)
Dicks MDJ, Rose LM, Russell RA, Bowman LAH, Graham C, Jimenez-Guardeno JM, Doores KJ, Malim MH, Draper SJ, Howarth M, Biswas S
Mol Ther (2022) 30 pp. 3639-3657 [ DOI: doi:10.1016/j.ymthe.2022.08.002 Pubmed: 35949171 ]
Dicks MDJ, Rose LM, Russell RA, Bowman LAH, Graham C, Jimenez-Guardeno JM, Doores KJ, Malim MH, Draper SJ, Howarth M, Biswas S
Mol Ther (2022) 30 pp. 3639-3657 [ DOI: doi:10.1016/j.ymthe.2022.08.002 Pubmed: 35949171 ]
Structure of a nanoparticle for a COVID-19 vaccine candidate
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7b3y
Q-score: 0.35
Tan TK, Rijal P, Rahikainen R, Keeble AH, Schimanski L, Hussain S, Harvey R, Hayes JWP, Edwards JC, McLean RK, Martini V, Pedrera M, Thakur N, Conceicao C, Dietrich I, Shelton H, Ludi A, Wilsden G, Browning C, Zagrajek AK, Bialy D, Bhat S, Stevenson-Leggett P, Hollinghurst P, Tully M, Moffat K, Chiu C, Waters R, Gray A, Azhar M, Mioulet V, Newman J, Asfor AS, Burman A, Crossley S, Hammond JA, Tchilian E, Charleston B, Bailey D, Tuthill TJ, Graham SP, Duyvesteyn HME, Malinauskas T, Huo J, Tree JA, Buttigieg KR, Owens RJ, Carroll MW, Daniels RS, McCauley JW, Stuart DI, Huang KA, Howarth M, Townsend AR
Nat Commun (2021) 12 pp. 542-542 [ DOI: doi:10.1038/s41467-020-20654-7 Pubmed: 33483491 ]