The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8ijq
Q-score: 0.461
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8ijr
Q-score: 0.485
Hu K, Zhang Q, Chen Y, Yang J, Xia Y, Rao B, Li S, Shen Y, Cao M, Lu H, Qin A, Jiang XC, Yao D, Zhao J, Zhou L, Cao Y
Nat Struct Mol Biol (2024) 31 pp. 884-895 [ DOI: doi:10.1038/s41594-024-01237-2 Pubmed: 38388831 ]
- Phosphoric acid mono-(2-amino-ethyl) ester (141 Da, Ligand)
- Sphingomyelin synthase-related protein 1 (48 kDa, Protein from Homo sapiens)
- The cryo-em structure of human sphingomyelin synthase-related protein in complex with diacylglycerol/phosphoethanolamine (Complex from Homo sapiens)
- (2s)-1-(hexadecanoyloxy)-3-hydroxypropan-2-yl (11z)-octadec-11-enoate (594 Da, Ligand)
Resolution: 3.74 Å
EM Method: Single-particle
Fitted PDBs: 8w9w
Q-score: 0.377
Hu K, Zhang Q, Chen Y, Yang J, Xia Y, Rao B, Li S, Shen Y, Cao M, Lu H, Qin A, Jiang XC, Yao D, Zhao J, Zhou L, Cao Y
Nat Struct Mol Biol (2024) 31 pp. 884-895 [ DOI: doi:10.1038/s41594-024-01237-2 Pubmed: 38388831 ]
- Phosphoric acid mono-(2-amino-ethyl) ester (141 Da, Ligand)
- Sphingomyelin synthase-related protein 1 (31 kDa, Protein from Homo sapiens)
- The cryo-em structure of human sphingomyelin synthase-related protein in complex with ceramide/phosphoethanolamine (Complex from Homo sapiens)
- ~{n}-[(~{z},2~{s},3~{r})-1,3-bis(oxidanyl)heptadec-4-en-2-yl]dodecanamide (467 Da, Ligand)
The cryo-EM structure of human sphingomyelin synthase-related protein
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8w9y
Q-score: 0.392
V. cholerae TniQ-Cascade complex with Type III-B crRNA
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8fuk
Q-score: 0.48
To Be Published
- Crispr-associated protein cas8 (72 kDa, Protein from Vibrio cholerae)
- Cas7 (39 kDa, Protein from Vibrio cholerae)
- Tniq (45 kDa, Protein from Vibrio cholerae)
- Cas6 (23 kDa, Protein from Vibrio cholerae)
- Type iii-b crrna (19 kDa, RNA from metagenome)
- Type i-f tniq-cascade with type iii-b crrna (450 kDa, Complex from Vibrio cholerae)
The cryo-EM structure of hAE2 with DIDS
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 8gv8
Q-score: 0.555
Zhang Q, Jian L, Yao D, Rao B, Xia Y, Hu K, Li S, Shen Y, Cao M, Qin A, Zhao J, Cao Y
Nat Commun (2023) 14 pp. 1812-1812 [ Pubmed: 37002221 DOI: doi:10.1038/s41467-023-37557-y ]
- Hae2 with dids (137 kDa, Complex from Homo sapiens)
- 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid} (464 Da, Ligand)
- Anion exchange protein 2 (137 kDa, Protein from Homo sapiens)
The cryo-EM structure of hAE2 with chloride ion
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8gv9
Q-score: 0.549
Zhang Q, Jian L, Yao D, Rao B, Xia Y, Hu K, Li S, Shen Y, Cao M, Qin A, Zhao J, Cao Y
Nat Commun (2023) 14 pp. 1812-1812 [ Pubmed: 37002221 DOI: doi:10.1038/s41467-023-37557-y ]
- Anion exchange protein 2 (137 kDa, Protein from Homo sapiens)
- Anion exchange protein 2 with chloride ion (137 kDa, Complex from Homo sapiens)
- Chloride ion (35 Da, Ligand)
The intermediate structure of hAE2 in basic pH
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8gva
Q-score: 0.519
Zhang Q, Jian L, Yao D, Rao B, Xia Y, Hu K, Li S, Shen Y, Cao M, Qin A, Zhao J, Cao Y
Nat Commun (2023) 14 pp. 1812-1812 [ Pubmed: 37002221 DOI: doi:10.1038/s41467-023-37557-y ]
- Anion exchange protein 2 (137 kDa, Protein from Homo sapiens)
- Anion exchange protein 2 (137 kDa, Complex from Homo sapiens)
The cryo-EM structure of hAE2 with bicarbonate
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8gvc
Q-score: 0.571
Zhang Q, Jian L, Yao D, Rao B, Xia Y, Hu K, Li S, Shen Y, Cao M, Qin A, Zhao J, Cao Y
Nat Commun (2023) 14 pp. 1812-1812 [ Pubmed: 37002221 DOI: doi:10.1038/s41467-023-37557-y ]
- Anion exchange protein 2 (137 kDa, Protein from Homo sapiens)
- Bicarbonate ion (61 Da, Ligand)
- Hae2 with bicarbonate (137 kDa, Complex from Homo sapiens)
The asymmetry structure of hAE2
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 8gve
Q-score: 0.509
Zhang Q, Jian L, Yao D, Rao B, Xia Y, Hu K, Li S, Shen Y, Cao M, Qin A, Zhao J, Cao Y
Nat Commun (2023) 14 pp. 1812-1812 [ Pubmed: 37002221 DOI: doi:10.1038/s41467-023-37557-y ]
- Anion exchange protein 2 (137 kDa, Protein from Homo sapiens)
- Anion exchange protein 2 (137 kDa, Complex from Homo sapiens)