KSHV glycoprotein B ectodomain, postfusion form
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9cu4
Q-score: 0.492
Ito F, Zhen J, Xie G, Huang H, Silva JC, Wu T-T, Zhou ZH
J Virol (2025) pp. e0153324-e0153324 [ Pubmed: 39818969 DOI: doi:10.1128/jvi.01533-24 ]
- Ectodomain of kshv glycoprotein b in postfusion form (230 kDa, Cellular component from Human gammaherpesvirus 8)
- Orf8 (66 kDa, Protein from Human gammaherpesvirus 8)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form
Ito F, Li Z, Minakhin L, Chandramouly G, Tyagi M, Betsch R, Krais JJ, Taberi B, Vekariya U, Calbert M, Skorski T, Johnson N, Chen XS, Pomerantz RT
Nat Commun (2024) 15 pp. 7003-7003 [ DOI: doi:10.1038/s41467-024-51351-4 Pubmed: 39143110 ]
Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form
Ito F, Li Z, Minakhin L, Chandramouly G, Tyagi M, Betsch R, Krais JJ, Taberi B, Vekariya U, Calbert M, Skorski T, Johnson N, Chen XS, Pomerantz RT
Nat Commun (2024) 15 pp. 7003-7003 [ DOI: doi:10.1038/s41467-024-51351-4 Pubmed: 39143110 ]
Human DNA polymerase theta helicase domain in complex with ssDNA, dimer form
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8w0a
Q-score: 0.435
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ DOI: doi:10.1101/2024.06.07.597860 Pubmed: 38895274 ]
- Human dna polymerase theta helicase domain in complex with ssdna (253 kDa, Complex from Homo sapiens)
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*t)-3') (13 kDa, DNA from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9asj
Q-score: 0.411
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ DOI: doi:10.1101/2024.06.07.597860 Pubmed: 38895274 ]
- Human dna polymerase theta helicase domain in complex with inhibitor amp-pnp (199 kDa, Complex from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain dimer, apo-form
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9ask
Q-score: 0.389
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ DOI: doi:10.1101/2024.06.07.597860 Pubmed: 38895274 ]
- Human dna polymerase theta helicase domain dimer, apo-form (199 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain tetramer, apo-form
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9asl
Q-score: 0.392
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ DOI: doi:10.1101/2024.06.07.597860 Pubmed: 38895274 ]
- Human dna polymerase theta helicase domain tetramer, apo-form (398 kDa, Complex from Homo sapiens)
- Dna polymerase theta (99 kDa, Protein from Homo sapiens)
Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9c5q
Q-score: 0.479
Ito F, Li Z, Minakhin L, Khant HA, Pomerantz RT, Chen XS
bioRxiv (2024) [ DOI: doi:10.1101/2024.06.07.597860 Pubmed: 38895274 ]
Resolution: 2.33 Å
EM Method: Single-particle
Fitted PDBs: 8ud2
Q-score: 0.672
SARS-CoV-2 Nsp15 bound to poly(A/U) RNA, consensus form
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 8ud3
Q-score: 0.605
Ito F, Yang H, Zhou ZH, Chen XS
Protein Cell (2024) 15 pp. 547-552 [ Pubmed: 38613382 DOI: doi:10.1093/procel/pwae009 ]
- Rna (35-mer) (11 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Homohexamer of nsp15 in complex with poly(a/u) rna (262 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Rna (35-mer) (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 15 (40 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)