Zorya anti-bacteriophage defense system ZorC WT
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8r68
Q-score: 0.268
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
Nature (2024) [ DOI: doi:10.1038/s41586-024-08493-8 Pubmed: 39662505 ]
Zorya anti-bacteriophage defense system ZorD apo form
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8qy7
Q-score: 0.571
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
Nature (2024) [ DOI: doi:10.1038/s41586-024-08493-8 Pubmed: 39662505 ]
Zorya anti-bacteriophage defense system ZorD in complex with ATP-gamma-S
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 8qyc
Q-score: 0.565
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
Nature (2024) [ DOI: doi:10.1038/s41586-024-08493-8 Pubmed: 39662505 ]
Zorya anti-bacteriophage defense system ZorAB
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 8qyd
Q-score: 0.506
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
Nature (2024) [ DOI: doi:10.1038/s41586-024-08493-8 Pubmed: 39662505 ]
- Water (18 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Zorya anti-bacteriophage defense system zorab (Cellular component from Escherichia coli)
- Palmitic acid (256 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Membrane protein (28 kDa, Protein from Escherichia coli)
- Anti-phage defense zorab system zora (80 kDa, Protein from Escherichia coli)
- Cardiolipin (1 kDa, Ligand)
Zorya anti-bacteriophage defense system ZorAB ZorA E86A_E89A, Calcium binding site mutation
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8qyh
Q-score: 0.51
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
Nature (2024) [ DOI: doi:10.1038/s41586-024-08493-8 Pubmed: 39662505 ]
- Zorya anti-bacteriophage defense system zorab zora e86a_e89a, calcium binding site mutation (Cellular component from Escherichia coli)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Anti-phage defense zorab system zora (31 kDa, Protein from Escherichia coli)
- Membrane protein (28 kDa, Protein from Escherichia coli)
- Cardiolipin (1 kDa, Ligand)
- Water (18 Da, Ligand)
Zorya anti-bacteriophage defense system ZorAB, ZorA delta_359-592, ZorA tail middle deletion.
Resolution: 2.07 Å
EM Method: Single-particle
Fitted PDBs: 8qyk
Q-score: 0.544
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
Nature (2024) [ DOI: doi:10.1038/s41586-024-08493-8 Pubmed: 39662505 ]
- Calcium ion (40 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Anti-phage defense zorab system zora (54 kDa, Protein from Escherichia coli)
- Membrane protein (28 kDa, Protein from Escherichia coli)
- Cardiolipin (1 kDa, Ligand)
- Zorya anti-bacteriophage defense system zorab, zora delta_359-592, zora tail middle deletion. (Cellular component from Escherichia coli)
- Water (18 Da, Ligand)
Zorya anti-bacteriophage defense system ZorAB, ZorA delta_435-729, ZorA tail tip deletion.
Resolution: 2.56 Å
EM Method: Single-particle
Fitted PDBs: 8qyy
Q-score: 0.448
Hu H, Popp PF, Hughes TCD, Roa-Eguiara A, Rutbeek NR, Martin FJO, Hendriks IA, Payne LJ, Yan Y, Humolli D, Klein-Sousa V, Songailiene I, Wang Y, Nielsen ML, Berry RM, Harms A, Erhardt M, Jackson SA, Taylor NMI
Nature (2024) [ DOI: doi:10.1038/s41586-024-08493-8 Pubmed: 39662505 ]
- Calcium ion (40 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Anti-phage defense zorab system zora (48 kDa, Protein from Escherichia coli)
- Zorya anti-bacteriophage defense system zorab, zora delta_435-729, zora tail tip deletion. (Cellular component from Escherichia coli)
- Membrane protein (28 kDa, Protein from Escherichia coli)
- Cardiolipin (1 kDa, Ligand)
- Water (18 Da, Ligand)
Cryo-EM micrographs of anti-CRISPR associated protein Aca2 bound to its RNA
Birkholz N, Kamata K, Feussner M, Wilkinson ME, Cuba Samaniego C, Migur A, Kimanius D, Ceelen M, Went SC, Usher B, Blower TR, Brown CM, Beisel CL, Weinberg Z, Fagerlund RD, Jackson SA, Fineran PC
Nature (2024) 631 pp. 670-677 [ Pubmed: 38987591 DOI: 10.1038/s41586-024-07644-1 ]
Image sets:
Aca2 from Pectobacterium phage ZF40 bound to RNA
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8w35
Q-score: 0.558
Birkholz N, Kamata K, Feussner M, Wilkinson ME, Cuba Samaniego C, Migur A, Kimanius D, Ceelen M, Went SC, Usher B, Blower TR, Brown CM, Beisel CL, Weinberg Z, Fagerlund RD, Jackson SA, Fineran PC
Nature (2024) 631 pp. 670-677 [ Pubmed: 38987591 DOI: doi:10.1038/s41586-024-07644-1 ]