Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8ezj
Q-score: 0.399
Duan HD, Jain BK, Li H, Graham TR, Li H
Nat Commun (2024) 15 pp. 1942-1942 [ DOI: doi:10.1038/s41467-024-46304-w Pubmed: 38431634 ]
- Adp-ribosylation factor-like protein 1 (20 kDa, Protein from Saccharomyces cerevisiae)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Arf guanine-nucleotide exchange factor 2 (168 kDa, Protein from Saccharomyces cerevisiae)
- Gea2 homodimer in complex with two arl1 monomers (379 kDa, Complex from Saccharomyces cerevisiae)
Cryo-EM structure of the S. cerevisiae guanine nucleotide exchange factor Gea2
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8ezq
Q-score: 0.329
Duan HD, Jain BK, Li H, Graham TR, Li H
Nat Commun (2024) 15 pp. 1942-1942 [ DOI: doi:10.1038/s41467-024-46304-w Pubmed: 38431634 ]
- Stand-alone gea2 homodimer (337 kDa, Complex from Saccharomyces cerevisiae)
- Arf guanine-nucleotide exchange factor 2 (168 kDa, Protein from Saccharomyces cerevisiae)
Structure of the S. cerevisiae P4B ATPase lipid flippase in the E2P state
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7rd6
Q-score: 0.439
Bai L, Jain BK, You Q, Duan HD, Takar M, Graham TR, Li H
Nat Commun (2021) 12 pp. 5963-5963 [ DOI: doi:10.1038/s41467-021-26273-0 Pubmed: 34645814 ]
- Probable phospholipid-transporting atpase neo1 (130 kDa, Protein from Saccharomyces cerevisiae)
- Beryllium trifluoride ion (66 Da, Ligand)
- P4b atpase lipid flippase in the e2p state (Complex from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
Structure of the S. cerevisiae P4B ATPase lipid flippase in the E2P-transition state
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7rd7
Q-score: 0.48
Bai L, Jain BK, You Q, Duan HD, Takar M, Graham TR, Li H
Nat Commun (2021) 12 pp. 5963-5963 [ DOI: doi:10.1038/s41467-021-26273-0 Pubmed: 34645814 ]
- Probable phospholipid-transporting atpase neo1 (130 kDa, Protein from Saccharomyces cerevisiae)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- P4b atpase lipid flippase in the e2p-transition state (Complex from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
Structure of the S. cerevisiae P4B ATPase lipid flippase in the E1-ATP state
Resolution: 5.64 Å
EM Method: Single-particle
Fitted PDBs: 7rd8
Q-score: 0.195
Bai L, Jain BK, You Q, Duan HD, Takar M, Graham TR, Li H
Nat Commun (2021) 12 pp. 5963-5963 [ DOI: doi:10.1038/s41467-021-26273-0 Pubmed: 34645814 ]
- Probable phospholipid-transporting atpase neo1 (130 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Phosphomethylphosphonic acid adenylate ester (505 Da, Ligand)
- P4b atpase lipid flippase in the e1-atp state (Complex from Saccharomyces cerevisiae)
Resolution: 3.98 Å
EM Method: Single-particle
Fitted PDBs: 7ky5
Q-score: 0.295
Bai L, You Q, Jain BK, Duan HD, Kovach A, Graham TR, Li H
eLife (2020) 9 [ Pubmed: 33320091 DOI: doi:10.7554/eLife.62163 ]
- Phospholipid-transporting atpase dnf2 (182 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- S. cerevisiae phosphatidylcholine flippase dnf2-lem3 complex in the e2p transition state (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Alkylphosphocholine resistance protein lem3 (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the S. cerevisiae phosphatidylcholine flippase Dnf1-Lem3 complex in the apo E1 state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7ky6
Q-score: 0.515
Bai L, You Q, Jain BK, Duan HD, Kovach A, Graham TR, Li H
eLife (2020) 9 [ Pubmed: 33320091 DOI: doi:10.7554/eLife.62163 ]
- Magnesium ion (24 Da, Ligand)
- S. cerevisiae phosphatidylcholine flippase dnf1-lem3 complex in the apo e1 state (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Alkylphosphocholine resistance protein lem3 (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Phospholipid-transporting atpase dnf1 (178 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the apo E1 state
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7ky7
Q-score: 0.469
Bai L, You Q, Jain BK, Duan HD, Kovach A, Graham TR, Li H
eLife (2020) 9 [ Pubmed: 33320091 DOI: doi:10.7554/eLife.62163 ]
- Phospholipid-transporting atpase dnf2 (182 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Alkylphosphocholine resistance protein lem3 (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- S. cerevisiae phosphatidylcholine flippase dnf2-lem3 complex in the apo e1 state (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Cholesterol (386 Da, Ligand)
Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the E1-ATP state
Resolution: 3.85 Å
EM Method: Single-particle
Fitted PDBs: 7ky8
Q-score: 0.452
Bai L, You Q, Jain BK, Duan HD, Kovach A, Graham TR, Li H
eLife (2020) 9 [ Pubmed: 33320091 DOI: doi:10.7554/eLife.62163 ]
- Phospholipid-transporting atpase dnf2 (182 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Alkylphosphocholine resistance protein lem3 (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- S. cerevisiae phosphatidylcholine flippase dnf2-lem3 complex in the e1-atp state (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Phosphomethylphosphonic acid adenylate ester (505 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the S. cerevisiae phosphatidylcholine flippase Dnf2-Lem3 complex in the E1-ADP state
Resolution: 4.05 Å
EM Method: Single-particle
Fitted PDBs: 7ky9
Q-score: 0.269
Bai L, You Q, Jain BK, Duan HD, Kovach A, Graham TR, Li H
eLife (2020) 9 [ Pubmed: 33320091 DOI: doi:10.7554/eLife.62163 ]
- Phospholipid-transporting atpase dnf2 (182 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Magnesium ion (24 Da, Ligand)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- S. cerevisiae phosphatidylcholine flippase dnf2-lem3 complex in the e1-adp state (Complex from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Alkylphosphocholine resistance protein lem3 (47 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)