Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 7sg4
Q-score: 0.355
Martinez DR, Schafer A, Gobeil S, Li D, De la Cruz G, Parks R, Lu X, Barr M, Stalls V, Janowska K, Beaudoin E, Manne K, Mansouri K, Edwards RJ, Cronin K, Yount B, Anasti K, Montgomery SA, Tang J, Golding H, Shen S, Zhou T, Kwong PD, Graham BS, Mascola JR, Montefiori DC, Alam SM, Sempowski G, Sempowski GD, Khurana S, Wiehe K, Saunders KO, Acharya P, Haynes BF, Baric RS
Sci Transl Med (2022) 14 pp. eabj7125-eabj7125 [ DOI: doi:10.1126/scitranslmed.abj7125 Pubmed: 34726473 ]
- Dh1047 heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (140 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- Dh1047 light chain (24 kDa, Protein from Homo sapiens)
- Sars-cov s protein in complex with receptor binding domain antibody dh1047 (Complex from Severe acute respiratory syndrome-related coronavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 7lwi
Q-score: 0.454
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7lwj
Q-score: 0.363
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 7lwk
Q-score: 0.501
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 7lwl
Q-score: 0.515
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7lwm
Q-score: 0.521
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 7lwn
Q-score: 0.502
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 1-RBD up conformation
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 7lwo
Q-score: 0.51
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Mink Cluster 5-associated SARS-CoV-2 spike protein (S-GSAS-D614G-delFV) in the 2-RBD up conformation
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 7lwp
Q-score: 0.442
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 7lwq
Q-score: 0.409
Gobeil SM, Janowska K, McDowell S, Mansouri K, Parks R, Stalls V, Kopp MF, Manne K, Li D, Wiehe K, Saunders KO, Edwards RJ, Korber B, Haynes BF, Henderson R, Acharya P
Science (2021) 373 [ Pubmed: 34168071 DOI: doi:10.1126/science.abi6226 ]