Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8tqi
Q-score: 0.499
Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters RM, Greninger AL, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe Jr JE
Nat Microbiol (2024) 9 pp. 2128-2143 [ DOI: doi:10.1038/s41564-024-01722-w Pubmed: 38858594 ]
- Hpiv3 hn in complex with rpiv3-23 and rpiv3-28 fabs (Complex from Human respirovirus 3)
- Heavy chain fab rpiv3-23 (24 kDa, Protein from Homo sapiens)
- Hemagglutinin-neuraminidase (50 kDa, Protein from Human respirovirus 3)
- Light chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Recombinant rpiv3-23 fab (Complex from Homo sapiens)
- Recombinant rpiv3-28 fab (Complex from Homo sapiens)
- Hemagglutinin-neuraminidase glycoprotein (Complex from Human respirovirus 3)
- Heavy chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Light chain fab rpiv3-23 (23 kDa, Protein from Homo sapiens)
Human parainfluenza virus type 3 prefusion F trimer in complex with rPIV3-18 Fab
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8tqk
Q-score: 0.451
Suryadevara N, Otrelo-Cardoso AR, Kose N, Hu YX, Binshtein E, Wolters RM, Greninger AL, Handal LS, Carnahan RH, Moscona A, Jardetzky TS, Crowe Jr JE
Nat Microbiol (2024) 9 pp. 2128-2143 [ DOI: doi:10.1038/s41564-024-01722-w Pubmed: 38858594 ]
- Rpiv3-18 heavy chain (Complex from Homo sapiens)
- Heavy chain fab rpiv3-18 (23 kDa, Protein from Homo sapiens)
- Light chain fab rpiv3-28 (23 kDa, Protein from Homo sapiens)
- Hpiv3 prefusion f trimer in complex with rpiv3-18 fab (Complex from Human respirovirus 3)
- Rpiv3-18 light chain (Complex from Homo sapiens)
- Fusion glycoprotein f0 (57 kDa, Protein from Human respirovirus 3)
- Fusion glycoprotein f0 (Complex from Human respirovirus 3)
Pennington LF, Gasser P, Kleinboelting S, Zhang C, Skiniotis G, Eggel A, Jardetzky TS
Nat Commun (2021) 12 [ DOI: 10.1038/s41467-021-27397-z Pubmed: 34862384 ]
Image sets:
RSV F trimer bound to RSV-199 Fab
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8dzw
Q-score: 0.569
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- Rsv-199 heavy chain protein (24 kDa, Protein from Homo sapiens)
- Rsv fusion protein complex with rsv-199 fab (Complex from Human respiratory syncytial virus A2)
- Rsv-199 light chain protein (22 kDa, Protein from Homo sapiens)
- Rsv fusion protein (53 kDa, Protein from Human respiratory syncytial virus A2)
HMPV F monomer bound to RSV-199 Fab
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8e2u
Q-score: 0.457
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- Rsv-199 heavy chain (24 kDa, Protein from Homo sapiens)
- Mpv fusion protein complex with rsv-199 fab (Complex from Human metapneumovirus)
- Rsv-199 light chain (22 kDa, Protein from Homo sapiens)
- Fusion glycoprotein f0 (47 kDa, Protein from Human metapneumovirus A)
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8eay
Q-score: 0.403
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- Fusion glycoprotein f0 (45 kDa, Protein from Human metapneumovirus A)
- Mpv fusion protein complex with 4i3 fab (Complex from Human metapneumovirus)
- 4i3 light chain protein (11 kDa, Protein from Homo sapiens)
- 4i3 heavy chain protein (13 kDa, Protein from Homo sapiens)
HMPV F dimer bound to RSV-199 Fab
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8ebp
Q-score: 0.426
Wen X, Suryadevara N, Kose N, Liu J, Zhan X, Handal LS, Williamson LE, Trivette A, Carnahan RH, Jardetzky TS, Crowe Jr JE
Cell Host Microbe (2023) 31 pp. 1288-1300.e6 [ Pubmed: 37516111 DOI: doi:10.1016/j.chom.2023.07.002 ]
- Rsv-199 light chain protein (22 kDa, Protein from Homo sapiens)
- Rsv-199 heavy chain protein (24 kDa, Protein from Homo sapiens)
- Mpv fusion protein complex with rsv-199 fab (Complex from Human metapneumovirus)
- Fusion glycoprotein f0 (47 kDa, Protein from Human metapneumovirus A)
Resolution: 3.43 Å
EM Method: Single-particle
Fitted PDBs: 7ram
Q-score: 0.452
Liu J, Vanarsdall A, Chen DH, Chin A, Johnson D, Jardetzky TS
Mbio (2021) 12 pp. e0262521-e0262521 [ DOI: doi:10.1128/mBio.02625-21 Pubmed: 34700375 ]
- Human platelet-derived growth factor receptor alpha extracellular domain (Complex from Homo sapiens)
- Envelope glycoprotein l (27 kDa, Protein from Human herpesvirus 5 strain AD169)
- Hcmv trimer in complex with receptor pdgfralpha (Complex from Human herpesvirus 5 strain AD169)
- Envelope glycoprotein h (80 kDa, Protein from Human herpesvirus 5 strain AD169)
- Platelet-derived growth factor receptor alpha (59 kDa, Protein from Homo sapiens)
- Envelope glycoprotein o (53 kDa, Protein from Human betaherpesvirus 5)
Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant
Resolution: 7.29 Å
EM Method: Single-particle
Fitted PDBs: 7sht
Q-score: 0.217
Pennington LF, Gasser P, Kleinboelting S, Zhang C, Skiniotis G, Eggel A, Jardetzky TS
Nat Commun (2021) 12 pp. 7069-7069 [ Pubmed: 34862384 DOI: doi:10.1038/s41467-021-27397-z ]
- Clone_7 variable fragment light chain (14 kDa, Protein from Homo sapiens)
- High affinity immunoglobulin epsilon receptor subunit alpha (22 kDa, Protein from Homo sapiens)
- Locked complex of ige-fc (g335c) and alpha chain of the high affinity ige receptor (w156c) bound to clone_7 scfv (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant epsilon (35 kDa, Protein from Homo sapiens)
- Clone_7 variable fragment heavy chain (13 kDa, Protein from Homo sapiens)