Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8j7f
Q-score: 0.555
Chen H, Xia Z, Dong J, Huang B, Zhang J, Zhou F, Yan R, Shi Y, Gong J, Jiang J, Huang Z, Jiang D
Nat Commun (2024) 15 pp. 3691-3691 [ Pubmed: 38693179 DOI: doi:10.1038/s41467-024-48125-3 ]
- Ile-ala-ala-ile-his-asn-ala-arg-arg-lys-lys-arg-glu-ala-ala-ala-ala-his-lys-ala (2 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Ion channel,voltage dependent ion channel,green fluorescent protein (fragment),voltage dependent ion channel,green fluorescent protein (fragment),ion transport domain-containing protein (33 kDa, Protein from Aequorea victoria)
- Ion channel complex (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Water (18 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8j7m
Q-score: 0.53
Chen H, Xia Z, Dong J, Huang B, Zhang J, Zhou F, Yan R, Shi Y, Gong J, Jiang J, Huang Z, Jiang D
Nat Commun (2024) 15 pp. 3691-3691 [ Pubmed: 38693179 DOI: doi:10.1038/s41467-024-48125-3 ]
- Ion channel (Complex from Homo sapiens)
- Ion channel,voltage dependent ion channel,green fluorescent protein (fragment),voltage dependent ion channel,green fluorescent protein (fragment),voltage dependent ion channel,green fluorescent protein (fragment) (90 kDa, Protein from Aequorea victoria)
- Cholesterol (386 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8j7h
Q-score: 0.448
Chen H, Xia Z, Dong J, Huang B, Zhang J, Zhou F, Yan R, Shi Y, Gong J, Jiang J, Huang Z, Jiang D
Nat Commun (2024) 15 pp. 3691-3691 [ Pubmed: 38693179 DOI: doi:10.1038/s41467-024-48125-3 ]
- Ile-ala-ala-ile-his-asn-ala-arg-arg-lys-lys-arg-glu-ala-ala-ala-ala-his-lys-ala (2 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Ion channel complex (Complex from Homo sapiens)
- Ion channel (91 kDa, Protein from Homo sapiens)
Human VMAT2 complex with serotonin
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8jsw
Q-score: 0.578
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ DOI: doi:10.1038/s41586-023-06926-4 Pubmed: 38081299 ]
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
- Transportera (Complex from Homo sapiens)
Human VMAT2 complex with tetrabenazine
Resolution: 3.36 Å
EM Method: Single-particle
Fitted PDBs: 8jta
Q-score: 0.506
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ DOI: doi:10.1038/s41586-023-06926-4 Pubmed: 38081299 ]
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Transporter2 (Complex from Homo sapiens)
- Tetrabenazine (317 Da, Ligand)
Human VMAT2 complex with reserpine
Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8jtc
Q-score: 0.481
Wu D, Chen Q, Yu Z, Huang B, Zhao J, Wang Y, Su J, Zhou F, Yan R, Li N, Zhao Y, Jiang D
Nature (2024) 626 pp. 427-434 [ DOI: doi:10.1038/s41586-023-06926-4 Pubmed: 38081299 ]
- Synaptic vesicular amine transporter (49 kDa, Protein from Homo sapiens)
- Reserpine (608 Da, Ligand)
- Transportera (Complex from Homo sapiens)
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8hir
Q-score: 0.518
Zhang J, Liu S, Fan J, Yan R, Huang B, Zhou F, Yuan T, Gong J, Huang Z, Jiang D
Cell Rep (2023) 42 pp. 112858-112858 [ Pubmed: 37494189 DOI: doi:10.1016/j.celrep.2023.112858 ]
- Zinc ion (65 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Potassium channel (Complex from Homo sapiens)
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Potassium channel subfamily t member 1 (139 kDa, Protein from Homo sapiens)
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8hk6
Q-score: 0.577
Zhang J, Liu S, Fan J, Yan R, Huang B, Zhou F, Yuan T, Gong J, Huang Z, Jiang D
Cell Rep (2023) 42 pp. 112858-112858 [ Pubmed: 37494189 DOI: doi:10.1016/j.celrep.2023.112858 ]
- Zinc ion (65 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Potassium channel subfamily t member 1 (139 kDa, Protein from Homo sapiens)
- Potassium channel (Complex from Homo sapiens)
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8hkf
Q-score: 0.546
Zhang J, Liu S, Fan J, Yan R, Huang B, Zhou F, Yuan T, Gong J, Huang Z, Jiang D
Cell Rep (2023) 42 pp. 112858-112858 [ Pubmed: 37494189 DOI: doi:10.1016/j.celrep.2023.112858 ]
- Ion channel (Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Potassium channel subfamily t member 1 (139 kDa, Protein from Homo sapiens)