Curved structure of mPIEZO1-S2472E
Resolution: 4.07 Å
EM Method: Single-particle
Fitted PDBs: 8ixn
Q-score: 0.301
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2024) [ DOI: doi:10.1016/j.neuron.2024.11.020 Pubmed: 39719701 ]
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- S2472e-curved structure (Complex from Mus musculus)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
Flattened structure of mPIEZO1-S2472E
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8ixo
Q-score: 0.445
Liu S, Yang X, Chen X, Zhang X, Jiang J, Yuan J, Liu W, Wang L, Zhou H, Wu K, Tian B, Li X, Xiao B
Neuron (2024) [ DOI: doi:10.1016/j.neuron.2024.11.020 Pubmed: 39719701 ]
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- S2472e-intermediate structure (Complex from Mus musculus)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Piezo-type mechanosensitive ion channel component 1 (292 kDa, Protein from Mus musculus)
Local map of Omicron Subvariant JN.1 RBD with ACE2
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8zbq
Q-score: 0.499
Cryo-EM structures of human XPR1 in closed states
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8x5b
Q-score: 0.575
Yan R, Chen H, Liu C, Zhao J, Wu D, Jiang J, Gong J, Jiang D
Nature (2024) 633 pp. 960-967 [ DOI: doi:10.1038/s41586-024-07852-9 Pubmed: 39169184 ]
- Transport (Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (54 kDa, Protein from Homo sapiens)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
- Cholesterol (386 Da, Ligand)
Cryo-EM structure of human XPR1 in open state
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8x5e
Q-score: 0.452
Yan R, Chen H, Liu C, Zhao J, Wu D, Jiang J, Gong J, Jiang D
Nature (2024) 633 pp. 960-967 [ DOI: doi:10.1038/s41586-024-07852-9 Pubmed: 39169184 ]
- [(2~{r})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate (717 Da, Ligand)
- Transport (Complex from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (54 kDa, Protein from Homo sapiens)