Cryo-EM structure of Bacillus RNAP and SPO1 gp33 complex
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 8xa6
Q-score: 0.254
Chen M, Jin Q, Zhang K, Wang Y, Chen H, Yu Z, Matthews S, Yuan S, Liu B
To Be Published
- Cryo-em structure of bacillus rnap and spo1 gp33 complex (Complex from Bacillus)
- Dna-directed rna polymerase subunit beta (133 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit beta' (134 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit epsilon (8 kDa, Protein from Bacillus)
- Gene 33 protein (11 kDa, Protein from Bacillus phage SPO1)
- Dna-directed rna polymerase subunit omega (7 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit delta (20 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit alpha (34 kDa, Protein from Bacillus)
Cryo-EM structure of Bacillus subtilis RNAP,sigA and SPO1 gp33 complex
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8xa7
Q-score: 0.511
Chen M, Jin Q, Zhang K, Wang Y, Chen H, Yu Z, Matthews S, Yuan S, Liu B
To Be Published
- Dna-directed rna polymerase subunit beta (133 kDa, Protein from Bacillus)
- Cryo-em structure of bacillus subtilis rnap,siga and spo1 gp33 complex (Complex from Bacillus)
- Dna-directed rna polymerase subunit beta' (134 kDa, Protein from Bacillus)
- Rna polymerase sigma factor siga (43 kDa, Protein from Bacillus)
- Gene 33 protein (11 kDa, Protein from Bacillus phage SPO1)
- Dna-directed rna polymerase subunit epsilon (8 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit omega (7 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit delta (20 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit alpha (34 kDa, Protein from Bacillus)
Cryo-EM structure of Bacillus RNAP and HelD complex
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8xa8
Q-score: 0.471
Chen M, Jin Q, Zhang K, Wang Y, Chen H, Yu Z, Matthews S, Yuan S, Liu B
To Be Published
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase subunit beta (133 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit beta' (134 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit epsilon (8 kDa, Protein from Bacillus)
- Dna helicase iv (90 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit omega (7 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit delta (20 kDa, Protein from Bacillus)
- Dna-directed rna polymerase subunit alpha (34 kDa, Protein from Bacillus)
- Cryo-em structure of bacillus rnap and held complex (Complex from Bacillus)
- Magnesium ion (24 Da, Ligand)
human RNA polymerase III pre-initiation complex closed DNA 1
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8ity
Q-score: 0.291
Hou H, Jin Q, Ren Y, Chen Z, Wang Q, Xu Y
Cell Res (2023) 33 pp. 565-568 [ Pubmed: 37165065 DOI: doi:10.1038/s41422-023-00819-x ]
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
- Dna (Complex)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 4 (159 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
- Rna polymerase iii pre-initiation complex closed complex 1 (Complex)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna (82-mer) (143 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Transcription factor tfiiib component b'' homolog (294 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (35 kDa, Protein from Homo sapiens)
- Dna (82-mer) (143 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Rna polymerase iii pre-initiation complex closed complex 1 (1 MDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
RNA polymerase III pre-initiation complex melting complex 1
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8iue
Q-score: 0.291
Hou H, Jin Q, Ren Y, Chen Z, Wang Q, Xu Y
Cell Res (2023) 33 pp. 565-568 [ Pubmed: 37165065 DOI: doi:10.1038/s41422-023-00819-x ]
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase (Complex)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
- Dna (Complex)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 4 (159 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Rna polymerase iii pre-initiation complex melting complex 1 (1 MDa, Complex from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Transcription factor tfiiib component b'' homolog (294 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Transcription factor (Complex)
- Human gene for u 6 rna (143 kDa, DNA from Homo sapiens)
- Dna (74-mer) (143 kDa, DNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
RNA polymerase III pre-initiation complex open complex 1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8iuh
Q-score: 0.341
Hou H, Jin Q, Ren Y, Chen Z, Wang Q, Xu Y
Cell Res (2023) 33 pp. 565-568 [ Pubmed: 37165065 DOI: doi:10.1038/s41422-023-00819-x ]
- Dna-directed rna polymerase iii subunit rpc6 (35 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc1 (24 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc7 (25 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc4 (7 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 1 (43 kDa, Protein from Homo sapiens)
- Dna (Complex)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc2 (14 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 4 (159 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i and iii subunit rpac1 (39 kDa, Protein from Homo sapiens)
- Snrna-activating protein complex subunit 3 (46 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc9 (16 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc2 (127 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Homo sapiens)
- Tfiiib (Complex)
- Dna-directed rna polymerase iii subunit rpc1 (155 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc3 (60 kDa, Protein from Homo sapiens)
- Transcription factor tfiiib component b'' homolog (294 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc4 (35 kDa, Protein from Homo sapiens)
- Dna (81-mer) (143 kDa, DNA from Homo sapiens)
- Dna (81-mer) (143 kDa, DNA from Homo sapiens)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc5 (80 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerases i and iii subunit rpac2 (15 kDa, Protein from Homo sapiens)
- Rna polymerase iii pre-initiation complex closed complex 1 (1 MDa, Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase iii, snapc (Complex)
- Dna-directed rna polymerase iii subunit rpc8 (22 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase iii subunit rpc10 (12 kDa, Protein from Homo sapiens)
- Transcription factor iiib 50 kda subunit (46 kDa, Protein from Homo sapiens)
- Iron/sulfur cluster (351 Da, Ligand)
- Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
The structure of INTAC-PEC complex
Resolution: 4.18 Å
EM Method: Single-particle
Fitted PDBs: 7ycx
Q-score: 0.311
Zheng H, Jin Q, Wang X, Qi Y, Liu W, Ren Y, Zhao D, Xavier Chen F, Cheng J, Chen X, Xu Y
Protein Cell (2023) 14 pp. 698-702 [ DOI: doi:10.1093/procel/pwad010 Pubmed: 36869814 ]
- Transcription elongation factor spt5 (121 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Dna/rna (Complex)
- Negative elongation factor a (57 kDa, Protein from Homo sapiens)
- Manganese (ii) ion (54 Da, Ligand)
- Dna-directed rna polymerase ii subunit (Complex)
- Integrator complex subunit 2 (134 kDa, Protein from Homo sapiens)
- Serine/threonine-protein phosphatase 2a catalytic subunit alpha isoform (35 kDa, Protein from Homo sapiens)
- Negative elongation factor b (65 kDa, Protein from Homo sapiens)
- Integrator complex subunit 4 (108 kDa, Protein from Homo sapiens)
- Unknown2 (1 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Sus scrofa)
- Integrator complex subunit 6 (100 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Sus scrofa)
- Negative elongation factor c/d (66 kDa, Protein from Homo sapiens)
- Unknown (2 kDa, Protein from Homo sapiens)
- Integrator complex subunit 5 (108 kDa, Protein from Homo sapiens)
- Integrator complex subunit 9 (73 kDa, Protein from Homo sapiens)
- Intac (Complex from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- Serine/threonine-protein phosphatase 2a 65 kda regulatory subunit a alpha isoform (65 kDa, Protein from Homo sapiens)
- Template dna (14 kDa, DNA from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase ii subunit rpb3 (30 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb1,dna-directed rna polymerase ii subunit rpb1, ctd1, ctd2, ctd3, ctd4 (217 kDa, Protein from Homo sapiens)
- Integrator complex subunit 1 (244 kDa, Protein from Homo sapiens)
- Non-template dna (14 kDa, DNA from synthetic construct)
- Integrator complex subunit 8 (113 kDa, Protein from Homo sapiens)
- Negative elongation factor e (43 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc5 (7 kDa, Protein from Sus scrofa)
- Integrator complex subunit 11 (67 kDa, Protein from Homo sapiens)
- Rna (7 kDa, RNA from synthetic construct)
- Dna-directed rna polymerase subunit beta (134 kDa, Protein from Sus scrofa)
- Intac-pec (Complex from Homo sapiens)
- Integrator complex subunit 7 (106 kDa, Protein from Homo sapiens)
- Transcription elongation factor spt4 (13 kDa, Protein from Homo sapiens)
- Rpb12 (7 kDa, Protein from Sus scrofa)
Structure of RPAP2-bound RNA polymerase II
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 7f4g
Q-score: 0.53
Wang X, Qi Y, Wang Z, Wang L, Song A, Tao B, Li J, Zhao D, Zhang H, Jin Q, Jiang YZ, Chen FX, Xu Y, Chen X
Cell Rep (2022) 39 pp. 110732-110732 [ DOI: doi:10.1016/j.celrep.2022.110732 Pubmed: 35476980 ]
- Zinc ion (65 Da, Ligand)
- Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Sus scrofa)
- Structure of rpap2-bound rna polymerase ii (Complex from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
- Rpb10 (7 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase subunit beta (134 kDa, Protein from Sus scrofa)
- Rpb1 (217 kDa, Protein from Sus scrofa)
- Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Sus scrofa)
- Rpap2 (69 kDa, Protein from Homo sapiens)
- Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
- Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
- Rpb12 (7 kDa, Protein from Sus scrofa)
Cryo-EM structure of the human MCT2
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7bp3
Q-score: 0.351
Zhang B, Jin Q, Xu L, Li N, Meng Y, Chang S, Zheng X, Wang J, Chen Y, Neculai D, Gao N, Zhang X, Yang F, Guo J, Ye S
Nat Commun (2020) 11 pp. 2429-2429 [ Pubmed: 32415067 DOI: doi:10.1038/s41467-020-16334-1 ]
- Monocarboxylate transporter 2 (Complex from Homo sapiens)
- Monocarboxylate transporter 2 (53 kDa, Protein from Homo sapiens)
The Cryo-EM Structure of Human Pannexin 1
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6m66
Q-score: 0.315
Jin Q, Zhang B, Zheng X, Li N, Xu L, Xie Y, Song F, Bhat EA, Chen Y, Gao N, Guo J, Zhang X, Ye S
Cell Res (2020) 30 pp. 449-451 [ Pubmed: 32246089 DOI: doi:10.1038/s41422-020-0310-0 ]
- Pannexin 1 (Complex from Homo sapiens)
- Pannexin-1 (49 kDa, Protein from Homo sapiens)