Structure of the TSC:WIPI3 lysosomal recruitment complex
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9ce3
Q-score: 0.382
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Isoform 4 of tuberin (199 kDa, Protein from Homo sapiens)
- Tbc1 domain family member 7 (35 kDa, Protein from Homo sapiens)
- Wd repeat domain phosphoinositide-interacting protein 3 (35 kDa, Protein from Homo sapiens)
- Tsc:wipi3 lysosomal recruitment complex (composite map) (733 kDa, Complex from Homo sapiens)
- Unknown fragment (1 kDa, Protein from Homo sapiens)
- Hamartin (133 kDa, Protein from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (consensus reconstruction)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; core)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; TSC1 N-terminus)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; TBC1D7)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; TBC1D7/TSC2)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; WIPI3)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)
The WIPI3:TSC lysosomal docking complex (focused reconstruction; WIPI3 TSC2)
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM
Sci Adv (2024) 10 pp. eadr5807-eadr5807 [ Pubmed: 39565846 DOI: doi:10.1126/sciadv.adr5807 ]
- Tsc:wipi3 lysosomal recruitment complex (733 kDa, Complex from Homo sapiens)