S. cerevisiae pol alpha - replisome complex
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 8b9c
Q-score: 0.217
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911- [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
- Cell division control protein 45 (75 kDa, Protein from Saccharomyces cerevisiae)
- Chromosome segregation in meiosis protein 3 (36 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm4 (105 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm6 (113 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication complex gins protein psf3 (24 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication complex gins protein sld5 (33 kDa, Protein from Saccharomyces cerevisiae)
- Dna polymerase alpha subunit b (78 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm3 (111 kDa, Protein from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm7 (95 kDa, Protein from Saccharomyces cerevisiae)
- Minichromosome maintenance protein 5 (86 kDa, Protein from Saccharomyces cerevisiae)
- Mediator of replication checkpoint protein 1 (126 kDa, Protein from Saccharomyces cerevisiae)
- Dna primase small subunit (51 kDa, Protein from Saccharomyces cerevisiae)
- Topoisomerase 1-associated factor 1 (141 kDa, Protein from Saccharomyces cerevisiae)
- Dna polymerase alpha catalytic subunit a (167 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Dna primase large subunit (62 kDa, Protein from Saccharomyces cerevisiae)
- Lagging strand (32 kDa, DNA from Saccharomyces cerevisiae)
- Leading strand (26 kDa, DNA from Saccharomyces cerevisiae)
- Dna replication complex gins protein psf1 (24 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- Dna replication complex gins protein psf2 (25 kDa, Protein from Saccharomyces cerevisiae)
- S. cerevisiae replisome - pol alpha primase complex (Complex from Saccharomyces cerevisiae)
- Dna replication licensing factor mcm2 (98 kDa, Protein from Saccharomyces cerevisiae)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) [ DOI: doi:10.1016/j.molcel.2023.06.035 ]
S. cerevisiae replisome + Ctf4 + pol alpha. Unbinned, locally filtered.
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
Composite map - human replisome + Pol alpha
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
Human replisome + pol alpha. Not engaged on DNA.
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
Local refinement, Pri1:Pri2-CTD. Pol alpha primase associated budding yeast replisome.
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]
Jones ML, Aria V, Baris Y, Yeeles JTP
Mol Cell (2023) 83 pp. 2911-2924.e16 [ Pubmed: 37506699 DOI: doi:10.1016/j.molcel.2023.06.035 ]