KS-AT di-domain of mycobacterial Pks13 with endogenous KS ligand bound
Resolution: 1.94 Å
EM Method: Single-particle
Fitted PDBs: 7uk4
Q-score: 0.628
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
- Acyl transferase domain (Complex from Mycolicibacterium smegmatis MC2 155)
- Polyketide synthase pks13 (198 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Ketosynthase domain (Complex from Mycolicibacterium smegmatis MC2 155)
- Unknown ligand (312 Da, Ligand)
- Water (18 Da, Ligand)
- Mycobacterial polyketide synthase 13 (Complex from Mycolicibacterium smegmatis MC2 155)
KS-AT domains of mycobacterial Pks13 with inward AT conformation
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8cuz
Q-score: 0.522
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
KS-AT domains of mycobacterial Pks13 with outward AT conformation
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8cv0
Q-score: 0.508
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
ACP1-KS-AT domains of mycobacterial Pks13
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8cv1
Q-score: 0.543
Kim SK, Dickinson MS, Finer-Moore J, Guan Z, Kaake RM, Echeverria I, Chen J, Pulido EH, Sali A, Krogan NJ, Rosenberg OS, Stroud RM
Nat Struct Mol Biol (2023) 30 pp. 296-308 [ DOI: doi:10.1038/s41594-022-00918-0 Pubmed: 36782050 ]
- Water (18 Da, Ligand)
- Mycobacterial polyketide synthase 13 (Complex from Mycolicibacterium smegmatis MC2 155)
- Unknown ligand (312 Da, Ligand)
- Polyketide synthase pks13 (194 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
Human Tom70 in complex with SARS CoV2 Orf9b
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 7kdt
Q-score: 0.473
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Huttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbolle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss 3rd FR, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech Jr TH, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, Garcia-Sastre A, Rassen JA, Grosse R, Rosenberg OS, Verba KA, Basler CF, Vignuzzi M, Peden AA, Beltrao P, Krogan NJ
Science (2020) 370 [ DOI: doi:10.1126/science.abe9403 Pubmed: 33060197 ]
- Mitochondrial import receptor subunit tom70 (56 kDa, Protein from Homo sapiens)
- Orf9b protein (10 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Orf9b-tom70 complex (Complex from Homo sapiens)