Cryo-EM structure of LRP2 at pH 7.5
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8em4
Q-score: 0.36
Beenken A, Cerutti G, Brasch J, Guo Y, Sheng Z, Erdjument-Bromage H, Aziz Z, Robbins-Juarez SY, Chavez EY, Ahlsen G, Katsamba PS, Neubert TA, Fitzpatrick AWP, Barasch J, Shapiro L
Cell (2023) 186 pp. 821- [ DOI: doi:10.1016/j.cell.2023.01.016 Pubmed: 36750096 ]
- Low-density lipoprotein receptor-related protein 2 (519 kDa, Protein from Mus musculus)
- Lrp2 at neutral ph (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-galactopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of LRP2 at pH 5.2
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8em7
Q-score: 0.423
Beenken A, Cerutti G, Brasch J, Guo Y, Sheng Z, Erdjument-Bromage H, Aziz Z, Robbins-Juarez SY, Chavez EY, Ahlsen G, Katsamba PS, Neubert TA, Fitzpatrick AWP, Barasch J, Shapiro L
Cell (2023) 186 pp. 821- [ DOI: doi:10.1016/j.cell.2023.01.016 Pubmed: 36750096 ]
- Low-density lipoprotein receptor-related protein 2 (519 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-galactopyranose (221 Da, Ligand)
- Lrp2 at endosomal ph (Complex from Mus musculus)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Omicron spike trimer bound with P3E6 (Local Refinement)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7ykj
Q-score: 0.369
Luo M, Zhou B, Reddem ER, Tang B, Chen B, Zhou R, Liu H, Liu L, Katsamba PS, Au KK, Man HO, To KK, Yuen KY, Shapiro L, Dang S, Ho DD, Chen Z
Emerg Microbes Infect (2023) 12 pp. 2146538-2146538 [ DOI: doi:10.1080/22221751.2022.2146538 Pubmed: 36354024 ]
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Complex from Homo sapiens)
- The complex of omicron spike trimer bound with p3e6 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- P3e6 heavy chain,p3e6 light chain (Complex)
- P3e6 heavy chain (13 kDa, Protein from Homo sapiens)
- P3e6 light chain (11 kDa, Protein from Homo sapiens)
Resolution: 3.76 Å
EM Method: Single-particle
Fitted PDBs: 8dxs
Q-score: 0.291
Luo M, Zhou B, Reddem ER, Tang B, Chen B, Zhou R, Liu H, Liu L, Katsamba PS, Au KK, Man HO, To KK, Yuen KY, Shapiro L, Dang S, Ho DD, Chen Z
Emerg Microbes Infect (2023) 12 pp. 2146538-2146538 [ DOI: doi:10.1080/22221751.2022.2146538 Pubmed: 36354024 ]
- Prefusion sars-cov-2 spike glycoprotein in complex with p2b4 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- P2b4 light chain (22 kDa, Protein from Homo sapiens)
- P2b4 heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)