KZ52 Fab fragment bound to Ebola GP, subtomogram average from a tight mask
Hastie KM, Salie ZL, Ke Z, Halfmann PJ, DeWald LE, McArdle S, Grinyo A, Davidson E, Schendel SL, Hariharan C, Norris MJ, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook MR, Doranz B, Crozier I, Kawaoka Y, Branco LM, Kuhn JH, Briggs JAG, Worwa G, Davis CW, Ahmed R, Saphire EO
Nat Commun (2025) 16 pp. 1293- [ DOI: doi:10.1038/s41467-025-56452-2 ]
KZ52 Fab fragment bound to Ebola GP, subtomogram average from a cylinder mask
Hastie KM, Salie ZL, Ke Z, Halfmann PJ, DeWald LE, McArdle S, Grinyo A, Davidson E, Schendel SL, Hariharan C, Norris MJ, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook MR, Doranz B, Crozier I, Kawaoka Y, Branco LM, Kuhn JH, Briggs JAG, Worwa G, Davis CW, Ahmed R, Saphire EO
Nat Commun (2025) 16 pp. 1293- [ DOI: doi:10.1038/s41467-025-56452-2 ]
3A6 Fab fragment bound to Ebola GP, subtomogram average from a cylinder mask
Hastie KM, Salie ZL, Ke Z, Halfmann PJ, DeWald LE, McArdle S, Grinyo A, Davidson E, Schendel SL, Hariharan C, Norris MJ, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook MR, Doranz B, Crozier I, Kawaoka Y, Branco LM, Kuhn JH, Briggs JAG, Worwa G, Davis CW, Ahmed R, Saphire EO
Nat Commun (2025) 16 pp. 1293- [ DOI: doi:10.1038/s41467-025-56452-2 ]
3A6 and KZ52 Fab fragments bound to Ebola GP, subtomogram average from a tight mask
Hastie KM, Salie ZL, Ke Z, Halfmann PJ, DeWald LE, McArdle S, Grinyo A, Davidson E, Schendel SL, Hariharan C, Norris MJ, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook MR, Doranz B, Crozier I, Kawaoka Y, Branco LM, Kuhn JH, Briggs JAG, Worwa G, Davis CW, Ahmed R, Saphire EO
Nat Commun (2025) 16 pp. 1293- [ DOI: doi:10.1038/s41467-025-56452-2 ]
3A6 and KZ52 Fab fragments bound to Ebola GP, subtomogram average from a cylinder mask
Hastie KM, Salie ZL, Ke Z, Halfmann PJ, DeWald LE, McArdle S, Grinyo A, Davidson E, Schendel SL, Hariharan C, Norris MJ, Yu X, Chennareddy C, Xiong X, Heinrich M, Holbrook MR, Doranz B, Crozier I, Kawaoka Y, Branco LM, Kuhn JH, Briggs JAG, Worwa G, Davis CW, Ahmed R, Saphire EO
Nat Commun (2025) 16 pp. 1293- [ DOI: doi:10.1038/s41467-025-56452-2 ]
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: B.1 variant 3 closed RBDs
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9crc
Q-score: 0.486
Ke Z, Peacock TP, Brown JC, Sheppard CM, Croll TI, Kotecha A, Goldhill DH, Barclay WS, Briggs JAG
EMBO J (2024) 43 pp. 6469-6495 [ Pubmed: 39543395 DOI: doi:10.1038/s44318-024-00303-1 ]
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: B.1 variant 1 open RBD
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9crd
Q-score: 0.41
Ke Z, Peacock TP, Brown JC, Sheppard CM, Croll TI, Kotecha A, Goldhill DH, Barclay WS, Briggs JAG
EMBO J (2024) 43 pp. 6469-6495 [ Pubmed: 39543395 DOI: doi:10.1038/s44318-024-00303-1 ]
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9cre
Q-score: 0.476
Ke Z, Peacock TP, Brown JC, Sheppard CM, Croll TI, Kotecha A, Goldhill DH, Barclay WS, Briggs JAG
EMBO J (2024) 43 pp. 6469-6495 [ Pubmed: 39543395 DOI: doi:10.1038/s44318-024-00303-1 ]
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Severe acute respiratory syndrome coronavirus 2 (Virus from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zinc ion (65 Da, Ligand)
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Alpha (B.1.1.7) variant 1 open RBD
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 9crf
Q-score: 0.349
Ke Z, Peacock TP, Brown JC, Sheppard CM, Croll TI, Kotecha A, Goldhill DH, Barclay WS, Briggs JAG
EMBO J (2024) 43 pp. 6469-6495 [ Pubmed: 39543395 DOI: doi:10.1038/s44318-024-00303-1 ]
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Gamma (P.1) variant 3 closed RBDs
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9crg
Q-score: 0.456
Ke Z, Peacock TP, Brown JC, Sheppard CM, Croll TI, Kotecha A, Goldhill DH, Barclay WS, Briggs JAG
EMBO J (2024) 43 pp. 6469-6495 [ Pubmed: 39543395 DOI: doi:10.1038/s44318-024-00303-1 ]