TRIF TIR Filament Cryo-EM Structure
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9dk8
Q-score: 0.47
Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 monomer state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8vh4
Q-score: 0.333
Li X, Zhu H, Huang BT, Li X, Kim H, Tan H, Zhang Y, Choi I, Peng J, Xu P, Sun J, Yue Z
Nat Commun (2024) 15 pp. 8434-8434 [ Pubmed: 39343966 DOI: doi:10.1038/s41467-024-52723-6 ]
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Rab12-lrrk2 (Complex from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Ras-related protein rab-12 (20 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cryo-EM structure of BsClpP-ADEP1 complex at pH 6.5
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7fep
Q-score: 0.543
Kim L, Lee BG, Kim M, Kim MK, Kwon DH, Kim H, Brotz-Oesterhelt H, Roh SH, Song HK
EMBO J (2022) 41 pp. e109755-e109755 [ Pubmed: 35593068 DOI: doi:10.15252/embj.2021109755 ]
- Atp-dependent clp protease proteolytic subunit (22 kDa, Protein from Bacillus subtilis)
- Cryo-em structure of bsclpp-adep1 complex at ph 6.5 (Complex)
- Bsclpp (Complex from Bacillus subtilis)
- Adep1 (Complex)
- Adep1 (736 Da, Protein from synthetic construct)
Cryo-EM structure of apo BsClpP at pH 6.5
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7feq
Q-score: 0.582
Cryo-EM structure of BsClpP-ADEP1 complex at pH 4.2
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7fer
Q-score: 0.443
Kim L, Lee BG, Kim M, Kim MK, Kwon DH, Kim H, Brotz-Oesterhelt H, Roh SH, Song HK
EMBO J (2022) 41 pp. e109755-e109755 [ Pubmed: 35593068 DOI: doi:10.15252/embj.2021109755 ]
- Atp-dependent clp protease proteolytic subunit (22 kDa, Protein from Bacillus subtilis)
- Bsclpp (Complex from Bacillus subtilis)
- Adep1 (Complex)
- Cryo-em structure of bsclpp-adep1 complex at ph 4.2 (Complex)
- Adep1 (736 Da, Protein from synthetic construct)
Cryo-EM structure of apo BsClpP at pH 4.2
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7fes
Q-score: 0.408
Cryo-EM structure of the Full-length disease type human Huntingtin
Resolution: 18.2 Å
EM Method: Single-particle
Fitted PDBs: 6yej
Q-score: 0.036
Jung T, Shin B, Tamo G, Kim H, Vijayvargia R, Leitner A, Marcaida MJ, Astorga-Wells J, Jung R, Aebersold R, Peraro MD, Hebert H, Seong IS, Song JJ
Structure (2020) 28 pp. 1035-1050.e8 [ DOI: doi:10.1016/j.str.2020.06.008 Pubmed: 32668197 ]
- Huntingtin (355 kDa, Protein from Homo sapiens)
- Full-length human disease-type huntingtin (350 kDa, Cellular component from Homo sapiens)
Cryo-EM 3D map of normal Huntingtin
Resolution: 9.6 Å
EM Method: Single-particle
Fitted PDBs: 6rmh
Q-score: 0.026
Jung T, Shin B, Tamo G, Kim H, Vijayvargia R, Leitner A, Marcaida MJ, Astorga-Wells J, Jung R, Aebersold R, Peraro MD, Hebert H, Seong IS, Song JJ
Structure (2020) 28 pp. 1035-1050.e8 [ DOI: doi:10.1016/j.str.2020.06.008 Pubmed: 32668197 ]
- Normal-type human huntingtin (350 kDa, Cellular component from Homo sapiens)
- Huntingtin (347 kDa, Protein from Homo sapiens)
Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 6pwv
Q-score: 0.188
Park SH, Ayoub A, Lee YT, Xu J, Kim H, Zheng W, Zhang B, Sha L, An S, Zhang Y, Cianfrocco MA, Su M, Dou Y, Cho US
Nat Commun (2019) 10 pp. 5540-5540 [ DOI: doi:10.1038/s41467-019-13550-2 Pubmed: 31804488 ]
- Set1/ash2 histone methyltransferase complex subunit ash2 (60 kDa, Protein from Homo sapiens)
- Dna (147-mer) (45 kDa, DNA from synthetic construct)
- Wd repeat-containing protein 5 (34 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Dna (147-mer) (45 kDa, DNA from synthetic construct)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Histone-lysine n-methyltransferase 2a (24 kDa, Protein from Homo sapiens)
- Human mll1 complex bound to the nucleosome (Complex from Xenopus laevis)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (13 kDa, Protein from Xenopus laevis)
- Protein dpy-30 homolog (11 kDa, Protein from Homo sapiens)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Retinoblastoma-binding protein 5 (59 kDa, Protein from Homo sapiens)
Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6pww
Q-score: 0.26
Park SH, Ayoub A, Lee YT, Xu J, Kim H, Zheng W, Zhang B, Sha L, An S, Zhang Y, Cianfrocco MA, Su M, Dou Y, Cho US
Nat Commun (2019) 10 pp. 5540-5540 [ DOI: doi:10.1038/s41467-019-13550-2 Pubmed: 31804488 ]
- Zinc ion (65 Da, Ligand)
- Wd repeat-containing protein 5 (34 kDa, Protein from Homo sapiens)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- Rbbp5, wdr5, and mll1 in complex with the nucleosome (Complex from Xenopus laevis)
- Histone-lysine n-methyltransferase 2a (24 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (13 kDa, Protein from Xenopus laevis)
- Dna (146-mer) (45 kDa, DNA from synthetic construct)
- Dna (146-mer) (45 kDa, DNA from synthetic construct)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Retinoblastoma-binding protein 5 (59 kDa, Protein from Homo sapiens)