Cryo-EM structure of human SOD1 (C6A/C111A) amyloid filament
Resolution: 3.18 Å
EM Method: Helical reconstruction
Fitted PDBs: 9jbp
Q-score: 0.488
Baek Y, Kim H, Lee D, Kim D, Jo E, Roh SH, Ha NC
PNAS (2025) 122 pp. e2408582122-e2408582122 [ DOI: doi:10.1073/pnas.2408582122 Pubmed: 39874287 ]
- Superoxide dismutase [cu-zn] (16 kDa, Protein from Homo sapiens)
- Unassigned poly-alanine model (698 Da, Protein from Homo sapiens)
- Amyloid filament of human c6a/c111a mutant sod1 protein (69 MDa, Complex from Homo sapiens)
Cryo-EM structure of Maltose Binding Protein
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 8ybe
Q-score: 0.676
To Be Published
- Water (18 Da, Ligand)
- Maltose binding protein monomer (Complex from Escherichia coli)
- Maltose/maltodextrin-binding periplasmic protein (40 kDa, Protein from Escherichia coli)
Human TRiC-PhLP2A complex in the closed state
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8i1u
Q-score: 0.506
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Aluminum fluoride (83 Da, Ligand)
- Complex of tric/cct-phlp2a treated with atp-alfx (1 MDa, Complex from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) (Complex)
- Human tric/cct complex (Complex from Homo sapiens)
The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 8i6j
Q-score: 0.404
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex of tric/cct and phlp2a (1 MDa, Complex from Homo sapiens)
- Tric/cct (Complex)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) (Complex from Homo sapiens)
Human TRiC-PhLP2A complex in the open state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8i9u
Q-score: 0.286
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Complex of human tric/cct and phlp2a (1 MDa, Complex)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) in human tric/cct complex (Complex from Homo sapiens)
- Human tric/cct complex (Complex from Homo sapiens)
The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state
Resolution: 4.22 Å
EM Method: Single-particle
Fitted PDBs: 8i9q
Q-score: 0.318
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]
- Complex of human tric/cct-phlp2a (1 MDa, Complex)
- T-complex protein 1 subunit delta from human tric/cct complex (Complex from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) (Complex from Homo sapiens)
Human TRiC-PhLP2A-actin complex in the closed state
Resolution: 4.42 Å
EM Method: Single-particle
Fitted PDBs: 8ib8
Q-score: 0.271
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]
- Complex of tric/cct, phlp2a, and actin treated with atp-alfx (1 MDa, Complex)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- Human actin (Complex from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- Actb protein (fragment) (41 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) (Complex from Homo sapiens)
- Human tric/cct complex (Complex from Homo sapiens)
Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7yc5
Q-score: 0.284
Kim JW, Heo K, Kim HJ, Yoo Y, Cho HS, Jang HJ, Lee HY, Ko IY, Woo JR, Cho YB, Lee JH, Yang HR, Shin HG, Choi HL, Hwang K, Kim S, Kim H, Chun K, Lee S
Antiviral Res (2023) 212 pp. 105576-105576 [ Pubmed: 36870394 DOI: doi:10.1016/j.antiviral.2023.105576 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Light chain from k202.b, bispecific antibody (49 kDa, Protein from Homo sapiens)
- Heavy chain from k202.b, bispecific antibody (49 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 spike in complex with k202.b bispecific antibody (Complex from Severe acute respiratory syndrome coronavirus 2)
- K202.b bispecific antibody (Complex)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of an apo-form of human DICER
Resolution: 4.04 Å
EM Method: Single-particle
Fitted PDBs: 7xw3
Q-score: 0.285
Lee YY, Lee H, Kim H, Kim VN, Roh SH
Nature (2023) 615 pp. 331-338 [ Pubmed: 36813958 DOI: doi:10.1038/s41586-023-05723-3 ]
- Endoribonuclease dicer (218 kDa, Protein from Homo sapiens)
- Monomeric form of human dicer (Complex from Homo sapiens)