Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8yht
Q-score: 0.373
Kim H, Adams C, Burtner A, Lee DS, Dobbins C, Criswell C, Coventry B, Kim HM, King N
To Be Published
- Minibinder 7.7 (6 kDa, Protein from Homo sapiens)
- Htlr3/minibinder 8.6 complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Toll-like receptor 3 (76 kDa, Protein from Homo sapiens)
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 8yhu
Q-score: 0.388
Kim H, Adams C, Burtner A, Lee DS, Dobbins C, Criswell C, Coventry B, Kim HM, King N
To Be Published
- Htlr3/minibinder 8.6 complex (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Minibinder 8.6 (6 kDa, Protein from Homo sapiens)
- Toll-like receptor 3 (76 kDa, Protein from Homo sapiens)
TRIF TIR Filament Cryo-EM Structure
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9dk8
Q-score: 0.47
Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 monomer state
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8vh4
Q-score: 0.333
Li X, Zhu H, Huang BT, Li X, Kim H, Tan H, Zhang Y, Choi I, Peng J, Xu P, Sun J, Yue Z
Nat Commun (2024) 15 pp. 8434-8434 [ Pubmed: 39343966 DOI: doi:10.1038/s41467-024-52723-6 ]
- Ras-related protein rab-12 (20 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Rab12-lrrk2 (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
Cryo-EM structure of Rab12-LRRK2 complex in the LRRK2 dimer state
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8vh5
Q-score: 0.248
Li X, Zhu H, Huang BT, Li X, Kim H, Tan H, Zhang Y, Choi I, Peng J, Xu P, Sun J, Yue Z
Nat Commun (2024) 15 pp. 8434-8434 [ Pubmed: 39343966 DOI: doi:10.1038/s41467-024-52723-6 ]
- Ras-related protein rab-12 (20 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Rab12-lrrk2 (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Leucine-rich repeat serine/threonine-protein kinase 2 (286 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
Cryo-EM structure of Maltose Binding Protein
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 8ybe
Q-score: 0.676
To Be Published
- Maltose/maltodextrin-binding periplasmic protein (40 kDa, Protein from Escherichia coli)
- Maltose binding protein monomer (Complex from Escherichia coli)
- Water (18 Da, Ligand)
The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 8i6j
Q-score: 0.404
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ DOI: doi:10.1038/s41467-024-45242-x Pubmed: 38307855 ]
- Complex of tric/cct and phlp2a (1 MDa, Complex from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- Tric/cct (Complex)
- Phlp2a (pdcl3) (Complex from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
Human TRiC-PhLP2A complex in the open state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8i9u
Q-score: 0.286
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ DOI: doi:10.1038/s41467-024-45242-x Pubmed: 38307855 ]
- Complex of human tric/cct and phlp2a (1 MDa, Complex)
- Human tric/cct complex (Complex from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) in human tric/cct complex (Complex from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state
Resolution: 4.22 Å
EM Method: Single-particle
Fitted PDBs: 8i9q
Q-score: 0.318
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ DOI: doi:10.1038/s41467-024-45242-x Pubmed: 38307855 ]
- T-complex protein 1 subunit delta from human tric/cct complex (Complex from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) (Complex from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- Complex of human tric/cct-phlp2a (1 MDa, Complex)
Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7yc5
Q-score: 0.284
Kim JW, Heo K, Kim HJ, Yoo Y, Cho HS, Jang HJ, Lee HY, Ko IY, Woo JR, Cho YB, Lee JH, Yang HR, Shin HG, Choi HL, Hwang K, Kim S, Kim H, Chun K, Lee S
Antiviral Res (2023) 212 pp. 105576-105576 [ DOI: doi:10.1016/j.antiviral.2023.105576 Pubmed: 36870394 ]
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain from k202.b, bispecific antibody (49 kDa, Protein from Homo sapiens)
- Heavy chain from k202.b, bispecific antibody (49 kDa, Protein from Homo sapiens)
- Cryo-em structure of sars-cov-2 spike in complex with k202.b bispecific antibody (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- K202.b bispecific antibody (Complex)