Human Consensus Olfactory Receptor OR52c in Complex with Octanoic Acid (OCA) and G Protein
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8hti
Q-score: 0.583
Choi C, Bae J, Kim S, Lee S, Kang H, Kim J, Bang I, Kim K, Huh WK, Seok C, Park H, Im W, Choi HJ
Nat Commun (2023) 14 pp. 8105-8105 [ Pubmed: 38062020 DOI: doi:10.1038/s41467-023-43983-9 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Consensus olfactory receptor or52c (36 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Complex of consensus olfactory receptor or52c in complex with octanoic acid, g protein and nanobody 35 (nb35) (140 kDa, Complex from Homo sapiens)
- Octanoic acid (caprylic acid) (144 Da, Ligand)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Nanobody 35 (15 kDa, Protein from Lama glama)
Human Consensus Olfactory Receptor OR52c in apo state, OR52c-bRIL
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 8j46
Q-score: 0.365
Human Consensus Olfactory Receptor OR52c in apo state, OR52c only
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 7yon
Q-score: 0.572
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ DOI: doi:10.1016/j.str.2022.11.010 Pubmed: 36525977 ]
- Complex structure of pyy(3-36)-y2r-gi-scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 2 (43 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Peptide yy(3-36) (4 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
- Pyy(3-36) (Complex)
- Single-chain antibody fv fragment (scfv16) (27 kDa, Protein from Mus musculus)
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 7yoo
Q-score: 0.531
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ DOI: doi:10.1016/j.str.2022.11.010 Pubmed: 36525977 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Neuropeptide y receptor type 2 (43 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein (Complex from Mus musculus)
- Single-chain antibody fv fragment (scfv16) (27 kDa, Protein from Mus musculus)
- Scfv16 (Complex)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Npy (Complex)
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi (Consensus map)
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ DOI: doi:10.1016/j.str.2022.11.010 Pubmed: 36525977 ]
- Guanine nucleotide-binding protein (Complex from Mus musculus)
- Npy (Complex)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Scfv16 (Complex)
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi (Focused map on NPY-Y2R)
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ DOI: doi:10.1016/j.str.2022.11.010 Pubmed: 36525977 ]
- Guanine nucleotide-binding protein (Complex from Mus musculus)
- Npy (Complex)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Scfv16 (Complex)