Human Consensus Olfactory Receptor OR52c in Complex with Octanoic Acid (OCA) and G Protein
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8hti
Q-score: 0.583
Choi C, Bae J, Kim S, Lee S, Kang H, Kim J, Bang I, Kim K, Huh WK, Seok C, Park H, Im W, Choi HJ
Nat Commun (2023) 14 pp. 8105-8105 [ Pubmed: 38062020 DOI: doi:10.1038/s41467-023-43983-9 ]
- Octanoic acid (caprylic acid) (144 Da, Ligand)
- Nanobody 35 (15 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Complex of consensus olfactory receptor or52c in complex with octanoic acid, g protein and nanobody 35 (nb35) (140 kDa, Complex from Homo sapiens)
- Consensus olfactory receptor or52c (36 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
Human Consensus Olfactory Receptor OR52c in apo state, OR52c-bRIL
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 8j46
Q-score: 0.365
Human Consensus Olfactory Receptor OR52c in apo state, OR52c only
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 7yon
Q-score: 0.572
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ Pubmed: 36525977 DOI: doi:10.1016/j.str.2022.11.010 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Pyy(3-36) (Complex)
- Neuropeptide y receptor type 2 (43 kDa, Protein from Homo sapiens)
- Peptide yy(3-36) (4 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein (Complex)
- Complex structure of pyy(3-36)-y2r-gi-scfv16 (Complex from Homo sapiens)
- Single-chain antibody fv fragment (scfv16) (27 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
- Water (18 Da, Ligand)
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 7yoo
Q-score: 0.531
Kang H, Park C, Choi YK, Bae J, Kwon S, Kim J, Choi C, Seok C, Im W, Choi HJ
Structure (2023) 31 pp. 44-57.e6 [ Pubmed: 36525977 DOI: doi:10.1016/j.str.2022.11.010 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Npy (Complex)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Scfv16 (Complex)
- Neuropeptide y receptor type 2 (43 kDa, Protein from Homo sapiens)
- Complex structure of npy-y2r-gi-scfv16 (Complex from Homo sapiens)
- Single-chain antibody fv fragment (scfv16) (27 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein (Complex from Mus musculus)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7vgx
Q-score: 0.501
Park C, Kim J, Ko SB, Choi YK, Jeong H, Woo H, Kang H, Bang I, Kim SA, Yoon TY, Seok C, Im W, Choi HJ
Nat Commun (2022) 13 pp. 853- [ DOI: doi:10.1038/s41467-022-28510-6 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Complex of neuropeptide y y1 receptor (npy1r) with its endogeneous peptide-agonist neuropeptide y (npy), g protein and g-protein stabilizing antibody fragement (scfv16) (160 kDa, Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Neuropeptide y (Complex)
- Neuropeptide y (4 kDa, Protein from Homo sapiens)
- Nucleotide-free g-protein heterotrimer (Complex from Homo sapiens)
- Neuropeptide y receptor type 1 (46 kDa, Protein from Homo sapiens)
- Neuropeptide y y1 receptor (npy1r) (Complex from Homo sapiens)
- Single-chain antibody fv fragment (scfv16) (27 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Single-chain antibody fv fragment (scfv16) (Complex from Mus musculus)