Cryo-EM structure of GPR156 of GPR156-miniGo-scFv16 complex (local refine)
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8ieb
Q-score: 0.435
Shin J, Park J, Jeong J, Lam JH, Qiu X, Wu D, Kim K, Lee JY, Robinson CV, Hyun J, Katritch V, Kim KP, Cho Y
Nat Struct Mol Biol (2024) 31 pp. 678-687 [ Pubmed: 38332368 DOI: doi:10.1038/s41594-024-01224-7 ]
- Gpr156 (131 MDa, Complex from Homo sapiens)
- Probable g-protein coupled receptor 156 (65 kDa, Protein from Homo sapiens)
- [(2r)-3-[(e)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate (760 Da, Ligand)
Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine)
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8iec
Q-score: 0.412
Shin J, Park J, Jeong J, Lam JH, Qiu X, Wu D, Kim K, Lee JY, Robinson CV, Hyun J, Katritch V, Kim KP, Cho Y
Nat Struct Mol Biol (2024) 31 pp. 678-687 [ Pubmed: 38332368 DOI: doi:10.1038/s41594-024-01224-7 ]
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Minigo heterotrimeric complex (Complex from Homo sapiens)
- Single-chain variable fragment scfv16 (27 kDa, Protein from Mus musculus)
- Minigo-scfv16 (27 MDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Scfv16 (Complex from Mus musculus)
Cryo-EM structure of GPR156-miniGo-scFv16 complex
Resolution: 3.33 Å
EM Method: Single-particle
Fitted PDBs: 8ied
Q-score: 0.402
Shin J, Park J, Jeong J, Lam JH, Qiu X, Wu D, Kim K, Lee JY, Robinson CV, Hyun J, Katritch V, Kim KP, Cho Y
Nat Struct Mol Biol (2024) 31 pp. 678-687 [ Pubmed: 38332368 DOI: doi:10.1038/s41594-024-01224-7 ]
- Gpr156 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (25 kDa, Protein from Homo sapiens)
- Probable g-protein coupled receptor 156 (65 kDa, Protein from Homo sapiens)
- Gpr156-minigo-scfv16 complex (27 MDa, Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Minigo heterotrimeric complex (Complex from Homo sapiens)
- [(2r)-3-[(e)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate (760 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Single-chain variable fragment scfv16 (27 kDa, Protein from Mus musculus)
- Scfv16 (Complex from Mus musculus)
Cryo-EM structure of GPR156A/B of G-protein free GPR156 (local refine)
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 8iei
Q-score: 0.507
Shin J, Park J, Jeong J, Lam JH, Qiu X, Wu D, Kim K, Lee JY, Robinson CV, Hyun J, Katritch V, Kim KP, Cho Y
Nat Struct Mol Biol (2024) 31 pp. 678-687 [ Pubmed: 38332368 DOI: doi:10.1038/s41594-024-01224-7 ]
- Probable g-protein coupled receptor 156 (65 kDa, Protein from Homo sapiens)
- Gpr156a/b (131 MDa, Complex from Homo sapiens)
- [(2r)-3-[(e)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate (760 Da, Ligand)
Cryo-EM structure of GPR156C/D of G-protein free GPR156 (local refine)
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8iep
Q-score: 0.511
Shin J, Park J, Jeong J, Lam JH, Qiu X, Wu D, Kim K, Lee JY, Robinson CV, Hyun J, Katritch V, Kim KP, Cho Y
Nat Struct Mol Biol (2024) 31 pp. 678-687 [ Pubmed: 38332368 DOI: doi:10.1038/s41594-024-01224-7 ]
- Gpr156c/d (131 MDa, Complex from Homo sapiens)
- Probable g-protein coupled receptor 156 (65 kDa, Protein from Homo sapiens)
- [(2r)-3-[(e)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate (760 Da, Ligand)
Cryo-EM structure of G-protein free GPR156
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8ieq
Q-score: 0.551
Shin J, Park J, Jeong J, Lam JH, Qiu X, Wu D, Kim K, Lee JY, Robinson CV, Hyun J, Katritch V, Kim KP, Cho Y
Nat Struct Mol Biol (2024) 31 pp. 678-687 [ Pubmed: 38332368 DOI: doi:10.1038/s41594-024-01224-7 ]