Infectious bronchitis virus core polymerase complex
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9cpo
Q-score: 0.477
Hoferle PJ, Anderson TK, Kirchdoerfer RN
bioRxiv (2024) [ DOI: doi:10.1101/2024.07.23.604833 Pubmed: 39091740 ]
- Non-structural protein 7 (8 kDa, Protein from Infectious bronchitis virus)
- Non-structural protein 8 (21 kDa, Protein from Infectious bronchitis virus)
- Rna-directed rna polymerase nsp12 (107 kDa, Protein from Infectious bronchitis virus)
- Core polymerase complex of the infectious bronchitis virus composed of nsp12, nsp8, nsp7, and an dsrna substrate (194 kDa, Complex from Infectious bronchitis virus)
- Rna template (10 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Rna primer (9 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
Porcine epidemic diarrhea virus complete core polymerase complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8urb
Q-score: 0.49
Anderson TK, Hoferle PJ, Lee KW, Coon JJ, Kirchdoerfer RN
bioRxiv (2023) [ Pubmed: 36993498 DOI: doi:10.1101/2023.03.15.532841 ]
- Nsp8 (21 kDa, Protein from Porcine epidemic diarrhea virus)
- Rna (55-mer) (17 kDa, RNA from synthetic construct)
- Nsp12 (108 kDa, Protein from Porcine epidemic diarrhea virus)
- Nsp7 (9 kDa, Protein from Porcine epidemic diarrhea virus)
- Rna (33-mer) (10 kDa, RNA from synthetic construct)
- Zinc ion (65 Da, Ligand)
- Core polymerase complex of the porcine epidemic diarrhea virus composed of nsp12, nsp7, nsp8, and a short rna substrate (185 kDa, Complex from Porcine epidemic diarrhea virus)
SARS-Coronavirus NSP12 bound to NSP7 and NSP8 co-factors
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6nur
Q-score: 0.491
Nat Commun (2019) 10 pp. 2342-2342 [ Pubmed: 31138817 DOI: doi:10.1038/s41467-019-10280-3 ]
- Nsp12 (109 kDa, Protein from Human SARS coronavirus)
- Nsp8 (21 kDa, Protein from Human SARS coronavirus)
- Sars-coronavirus nsp12 bound to nsp7 and nsp8 co-factors (160 kDa, Complex from SARS coronavirus)
- Zinc ion (65 Da, Ligand)
- Nsp7 (9 kDa, Protein from Human SARS coronavirus)
SARS-Coronavirus NSP12 bound to NSP8 co-factor
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6nus
Q-score: 0.383
Nat Commun (2019) 10 pp. 2342-2342 [ Pubmed: 31138817 DOI: doi:10.1038/s41467-019-10280-3 ]
- Nsp12 (109 kDa, Protein from Human SARS coronavirus)
- Nsp8 (21 kDa, Protein from Human SARS coronavirus)
- Zinc ion (65 Da, Ligand)
- Sars-coronavirus nsp12 bound to nsp7 and nsp8 co-factors (130 kDa, Complex from SARS coronavirus)
Ebola virus nucleoprotein - RNA complex
Resolution: 3.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 6nut
Q-score: 0.516
Kirchdoerfer RN, Saphire EO, Ward AB
Acta Crystallogr F Struct Biol Commun (2019) 75 pp. 340-347 [ Pubmed: 31045563 DOI: doi:10.1107/S2053230X19004424 ]
- Nucleoprotein (50 kDa, Protein from Zaire ebolavirus (strain Mayinga-76))
- Rna (5'-r(p*ap*ap*ap*ap*ap*a)-3') (1 kDa, RNA from Homo sapiens)
- Ebola virus nucleoprotein bound to rna (177 MDa, Complex from Ebola virus - Mayinga, Zaire, 1976)