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primary_citation_author:"Klepacki D"
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Escherichia coli 50S subunit in complex with the antimicrobial peptide Api137

Release date: May 22, 2024
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8rpy
Q-score: 0.519

Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R

Nat Commun (2024) 15 pp. 3945-3945 [ Pubmed: 38730238 DOI: doi:10.1038/s41467-024-48027-4 ]

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Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation I

Release date: May 22, 2024
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8rpz
Q-score: 0.557

Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R

Nat Commun (2024) 15 pp. 3945-3945 [ DOI: doi:10.1038/s41467-024-48027-4 Pubmed: 38730238 ]

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Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation II

Release date: May 22, 2024
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8rq0
Q-score: 0.557

Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R

Nat Commun (2024) 15 pp. 3945-3945 [ DOI: doi:10.1038/s41467-024-48027-4 Pubmed: 38730238 ]

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Escherichia coli 50S subunit in complex with the antimicrobial peptide Api88 - conformation III

Release date: May 22, 2024
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8rq2

Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R

Nat Commun (2024) 15 pp. 3945-3945 [ DOI: doi:10.1038/s41467-024-48027-4 Pubmed: 38730238 ]

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Wild-type Escherichia coli stalled ribosome with antibiotic radezolid

Release date: March 2, 2022
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 7s1i
Q-score: 0.575

Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T, Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS, Fujimori DG

Nat Struct Mol Biol (2022) 29 pp. 162-171 [ Pubmed: 35165456 DOI: doi:10.1038/s41594-022-00723-9 ]

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Wild-type Escherichia coli ribosome with antibiotic radezolid

Release date: March 2, 2022
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 7s1j
Q-score: 0.552

Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T, Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS, Fujimori DG

Nat Struct Mol Biol (2022) 29 pp. 162-171 [ DOI: doi:10.1038/s41594-022-00723-9 Pubmed: 35165456 ]

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Cfr-modified Escherichia coli stalled ribosome with antibiotic radezolid

Release date: Jan. 19, 2022
Resolution: 2.42 Å
EM Method: Single-particle
Fitted PDBs: 7s1k
Q-score: 0.531

Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T, Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS, Fujimori DG

Nat Struct Mol Biol (2022) 29 pp. 162-171 [ DOI: doi:10.1038/s41594-022-00723-9 Pubmed: 35165456 ]

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wild-type Escherichia coli stalled ribosome with antibiotic linezolid

Release date: Nov. 17, 2021
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 7s1g
Q-score: 0.574

Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T, Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS, Fujimori DG

Nat Struct Mol Biol (2022) 29 pp. 162-171 [ Pubmed: 35165456 DOI: doi:10.1038/s41594-022-00723-9 ]

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