Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1
Chen Q, Plasencia M, Li Z, Mukherjee S, Patra D, Chen CL, Klose T, Yao XQ, Kossiakoff AA, Chang L, Andrews PC, Tesmer JJG
Nature (2021) 595 pp. 600-605 [ Pubmed: 34262173 DOI: doi:10.1038/s41586-021-03721-x ]
- Rhodopsin kinase, rhodopsin (Complex from Bos taurus)
- Retinal (284 Da, Ligand)
- Rhodopsin kinase grk1 (61 kDa, Protein from Bos taurus)
- Rhodopsin kinase (grk1)-s5e/s488e/t489e in complex with rhodopsin stabilized by fab1 (Complex)
- Fab1 light chain (23 kDa, Protein from Homo sapiens)
- Fab1 heavy chain (24 kDa, Protein from Homo sapiens)
- Rhodopsin (39 kDa, Protein from Bos taurus)
- Fab heavy and light chains (Complex from Homo sapiens)
- Sangivamycin (309 Da, Ligand)
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6
Chen Q, Plasencia M, Li Z, Mukherjee S, Patra D, Chen CL, Klose T, Yao XQ, Kossiakoff AA, Chang L, Andrews PC, Tesmer JJG
Nature (2021) 595 pp. 600-605 [ Pubmed: 34262173 DOI: doi:10.1038/s41586-021-03721-x ]
- Rhodopsin kinase, rhodopsin (Complex from Bos taurus)
- Retinal (284 Da, Ligand)
- Rhodopsin kinase grk1 (61 kDa, Protein from Bos taurus)
- Rhodopsin kinase (grk1)-s5e/s488e/t489e in complex with rhodopsin stabilized by fab6 (Complex)
- Fab6 light chain (23 kDa, Protein from Homo sapiens)
- Rhodopsin (39 kDa, Protein from Bos taurus)
- Fab6 heavy chain (25 kDa, Protein from Homo sapiens)
- Fab6 heavy and light chains (Complex from Homo sapiens)
- Sangivamycin (309 Da, Ligand)
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6bf8
Q-score: 0.153
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
eLife (2018) 7 [ DOI: doi:10.7554/eLife.33572 Pubmed: 29596046 ]
- Insulin-degrading enzyme (111 kDa, Protein from Homo sapiens)
- Insulin degrading enzyme (100 kDa, Complex from Homo sapiens)
Cryo-EM structure of human insulin degrading enzyme
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 6bf6
Q-score: 0.162
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
eLife (2018) 7 [ DOI: doi:10.7554/eLife.33572 Pubmed: 29596046 ]
- Insulin-degrading enzyme (111 kDa, Protein from Homo sapiens)
- Insulin degrading enzyme (100 kDa, Complex from Homo sapiens)
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6b3q
Q-score: 0.394
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
eLife (2018) 7 [ DOI: doi:10.7554/eLife.33572 Pubmed: 29596046 ]
- Insulin degrading enzyme/insulin (100 kDa, Complex from Homo sapiens)
- Insulin-degrading enzyme (114 kDa, Protein from Homo sapiens)
- Insulin (11 kDa, Protein from Homo sapiens)
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 6b7y
Q-score: 0.157
Zhang Z, Liang WG, Bailey LJ, Tan YZ, Wei H, Wang A, Farcasanu M, Woods VA, McCord LA, Lee D, Shang W, Deprez-Poulain R, Deprez B, Liu DR, Koide A, Koide S, Kossiakoff AA, Li S, Carragher B, Potter CS, Tang WJ
eLife (2018) 7 [ DOI: doi:10.7554/eLife.33572 Pubmed: 29596046 ]
- Insulin-degrading enzyme (111 kDa, Protein from Homo sapiens)
- Insulin degrading enzyme (100 kDa, Complex from Homo sapiens)