Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 7cvy
Q-score: 0.178
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Fab heavy chain (23 kDa, Protein from Mus musculus)
- Chikungunya virus in complex with fab fragments of mab chk-124 (Complex)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab region of chk-124 (Cellular component from Mus musculus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7cvz
Q-score: 0.281
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Chikungunya virus in complex with fab fragments of mab chk-263 (Complex)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Fab light chain (23 kDa, Protein from Mus musculus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- Chk-263 fab (Cellular component from Mus musculus)
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7cw0
Q-score: 0.184
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Chikungunya virus in complex with mab chk-263 igg (Complex)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Fab region of chk-263 (Cellular component from Mus musculus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7cw2
Q-score: 0.316
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Localized reconstruction of subregions around the icosahedral 5-fold vertex of chikv:chk-263 fab complex (Complex)
- Fab light chain (23 kDa, Protein from Mus musculus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- Fab region of chk-263 (Cellular component from Mus musculus)
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 7cw3
Q-score: 0.117
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Subregions around the icosahedral 2-fold vertex of chikungunya virus in complexed with chk-263 igg (Complex from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Chikungunya virus (Complex from Mus musculus)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab region of chk-263 igg (Complex)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)