Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 7cvy
Q-score: 0.178
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Fab heavy chain (23 kDa, Protein from Mus musculus)
- Chikungunya virus in complex with fab fragments of mab chk-124 (Complex)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab region of chk-124 (Cellular component from Mus musculus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 7cvz
Q-score: 0.281
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Chikungunya virus in complex with fab fragments of mab chk-263 (Complex)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Fab light chain (23 kDa, Protein from Mus musculus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- Chk-263 fab (Cellular component from Mus musculus)
Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7cw0
Q-score: 0.184
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Chikungunya virus in complex with mab chk-263 igg (Complex)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Fab region of chk-263 (Cellular component from Mus musculus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7cw2
Q-score: 0.316
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Localized reconstruction of subregions around the icosahedral 5-fold vertex of chikv:chk-263 fab complex (Complex)
- Fab light chain (23 kDa, Protein from Mus musculus)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
- Chikungunya virus (Cellular component from Chikungunya virus)
- Fab region of chk-263 (Cellular component from Mus musculus)
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 7cw3
Q-score: 0.117
Zhou QF, Fox JM, Earnest JT, Ng TS, Kim AS, Fibriansah G, Kostyuchenko VA, Shi J, Shu B, Diamond MS, Lok SM
PNAS (2020) 117 pp. 27637-27645 [ DOI: doi:10.1073/pnas.2008051117 Pubmed: 33087569 ]
- Subregions around the icosahedral 2-fold vertex of chikungunya virus in complexed with chk-263 igg (Complex from Chikungunya virus)
- E2 glycoprotein (46 kDa, Protein from Chikungunya virus)
- Fab heavy chain (22 kDa, Protein from Mus musculus)
- Chikungunya virus (Complex from Mus musculus)
- Fab light chain (23 kDa, Protein from Mus musculus)
- Fab region of chk-263 igg (Complex)
- E1 glycoprotein (47 kDa, Protein from Chikungunya virus)
- Capsid protein (16 kDa, Protein from Chikungunya virus)
5-fold averaged density map of Paramecium bursaria Chlorella virus-1 (PBCV-1).
Cherrier MV, Kostyuchenko VA, Xiao C, Bowman VD, Battisti AJ, Yan X, Chipman PR, Baker TS, Van Etten JL, Rossmann MG
PNAS (2009) 106 pp. 11085-11089 [ Pubmed: 19541619 DOI: doi:10.1073/pnas.0904716106 ]
Asymmetric binding of transferrin receptor to parvovirus capsids.
Hafenstein S, Palermo LM, Kostyuchenko VA, Xiao C, Morais MC, Nelson CD, Bowman VD, Battisti AJ, Chipman PR, Parrish CR, Rossmann MG
PNAS (2007) 104 pp. 6585-6589 [ Pubmed: 17420467 DOI: doi:10.1073/pnas.0701574104 ]
Asymmetric binding of transferrin receptor to parvovirus capsids.
Resolution: 27.0 Å
EM Method: Single-particle
Fitted PDBs: 2nsu
Q-score: 0.028
Hafenstein S, Palermo LM, Kostyuchenko VA, Xiao C, Morais MC, Nelson CD, Bowman VD, Battisti AJ, Chipman PR, Parrish CR, Rossmann MG
PNAS (2007) 104 pp. 6585-6589 [ DOI: doi:10.1073/pnas.0701574104 Pubmed: 17420467 ]