The focused refinement of CCT4-PhLP2A from TRiC-PhLP2A complex in the open state
Resolution: 4.22 Å
EM Method: Single-particle
Fitted PDBs: 8i9q
Q-score: 0.318
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]
- Complex of human tric/cct-phlp2a (1 MDa, Complex)
- T-complex protein 1 subunit delta from human tric/cct complex (Complex from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) (Complex from Homo sapiens)
Human TRiC-PhLP2A-actin complex in the closed state
Resolution: 4.42 Å
EM Method: Single-particle
Fitted PDBs: 8ib8
Q-score: 0.271
Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH
Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]
- Complex of tric/cct, phlp2a, and actin treated with atp-alfx (1 MDa, Complex)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- Human actin (Complex from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- Actb protein (fragment) (41 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- Phlp2a (pdcl3) (Complex from Homo sapiens)
- Human tric/cct complex (Complex from Homo sapiens)
TRiC-substrate complex in ATP/AlFx closed state
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7lum
Q-score: 0.291
Knowlton JJ, Gestaut D, Ma B, Taylor G, Seven AB, Leitner A, Wilson GJ, Shanker S, Yates NA, Prasad BVV, Aebersold R, Chiu W, Frydman J, Dermody TS
PNAS (2021) 118 [ Pubmed: 33836586 DOI: doi:10.1073/pnas.2018127118 ]
- Human tric/cct complex (1 MDa, Complex from Homo sapiens)
- T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)