Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8bv5
Q-score: 0.357
Khanppnavar B, Schuster D, Lavriha P, Uliana F, Ozel M, Mehta V, Leitner A, Picotti P, Korkhov VM
EMBO Rep (2024) 25 pp. 1513-1540 [ DOI: doi:10.1038/s44319-024-00076-y Pubmed: 38351373 ]
- Structure of adenylyl cyclase 8 bound to stimulatory g protein, forskolin, atpalphas, and ca2+/calmodulin in lipid nanodisc (Complex from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (47 kDa, Protein from Bos taurus)
- Adenylyl cyclase 8 (Complex from Bos taurus)
- Adenylate cyclase type 8 (140 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)
- Calmodulin (Complex from Bos taurus)
- Forskolin (410 Da, Ligand)
- G protein alpha s (Complex from Bos taurus)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Khanppnavar B, Schuster D, Lavriha P, Uliana F, Ozel M, Mehta V, Leitner A, Picotti P, Korkhov VM
EMBO Rep (2024) 25 pp. 1513-1540 [ DOI: doi:10.1038/s44319-024-00076-y Pubmed: 38351373 ]
- Calmodulin (Protein from Bos taurus)
- Adenylyl cyclase 8 and g protein alpha s (Complex from Bos taurus)
- Adenylyl cyclase 8 (Protein from Bos taurus)
- G protein alpha s (Protein from Bos taurus)
- Calmodulin (Complex from Bos taurus)
- Structure of adenylyl cyclase 8 bound to stimulatory g protein, forskolin, atpalphas, and ca2+/calmodulin in lipid nanodisc (Complex)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8buz
Q-score: 0.409
Khanppnavar B, Schuster D, Lavriha P, Uliana F, Ozel M, Mehta V, Leitner A, Picotti P, Korkhov VM
EMBO Rep (2024) 25 pp. 1513-1540 [ DOI: doi:10.1038/s44319-024-00076-y Pubmed: 38351373 ]
- Forskolin (410 Da, Ligand)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (47 kDa, Protein from Bos taurus)
- Adenylate cyclase type 8 (140 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand)
- Structure of adenylyl cyclase 8 bound to stimulatory g protein, ca2+/calmodulin, forskolin, and mant-gtp (Complex)
- G protein alpha s (Complex from Bos taurus)
- Adenylyl cyclase 8 (Complex from Bos taurus)
- 5'-guanosine-diphosphate-monothiophosphate (539 Da, Ligand)
Khanppnavar B, Schuster D, Lavriha P, Uliana F, Ozel M, Mehta V, Leitner A, Picotti P, Korkhov VM
EMBO Rep (2024) 25 pp. 1513-1540 [ DOI: doi:10.1038/s44319-024-00076-y Pubmed: 38351373 ]
- Adenylyl cyclase 8 (Protein from Bos taurus)
- G protein alpha s (Protein from Bos taurus)
- Focused refinement of soluble domain of adenylyl cyclase 8 bound to stimulatory g protein, forskolin, and mant-gtp (Complex)
- G protein alpha s (Complex from Bos taurus)
- Adenylyl cyclase 8 (Complex from Bos taurus)
Khanppnavar B, Schuster D, Lavriha P, Uliana F, Ozel M, Mehta V, Leitner A, Picotti P, Korkhov VM
EMBO Rep (2024) 25 pp. 1513-1540 [ DOI: doi:10.1038/s44319-024-00076-y Pubmed: 38351373 ]
- Adenylyl cyclase 8 (Protein from Bos taurus)
- G protein alpha s (Protein from Bos taurus)
- Focused refinement of soluble domain of adenylyl cyclase 8 bound to stimulatory g protein, forskolin, and mant-gtp (Complex)
- G protein alpha s (Complex from Bos taurus)
- Adenylyl cyclase 8 (Complex from Bos taurus)
Structure of the rod CNG channel bound to calmodulin
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8bx7
Q-score: 0.48
Barret DCA, Schuster D, Rodrigues MJ, Leitner A, Picotti P, Schertler GFX, Kaupp UB, Korkhov VM, Marino J
PNAS (2023) 120 pp. e2300309120-e2300309120 [ Pubmed: 37011209 DOI: doi:10.1073/pnas.2300309120 ]
- Cgmp-gated cation channel alpha-1 (79 kDa, Protein from Bos taurus)
- Calmodulin-1 (16 kDa, Protein from Bos taurus)
- Cyclic nucleotide-gated cation channel beta-1 (155 kDa, Protein from Bos taurus)
- Native cng channel from retinal rods (410 kDa, Complex from Bos taurus)
The structure of the rod CNG channel bound to calmodulin
Barret DCA, Schuster D, Rodrigues MJ, Leitner A, Picotti P, Schertler GFX, Kaupp UB, Korkhov VM, Marino J
PNAS (2023) 120 pp. e2300309120-e2300309120 [ Pubmed: 37011209 DOI: doi:10.1073/pnas.2300309120 ]
- Native cng channel from retinal rods (410 kDa, Complex from Bos taurus)