EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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primary_citation_author:"Leitner A" AND xref_links:"cpx" AND software_ft:"CRYOSPARC"

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EMD-35122

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Human TRiC-PhLP2A complex in the closed state

Release date: Jan. 31, 2024
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8i1u
Q-score: 0.506

Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH

Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]

Sample:

Adenosine-5'-diphosphate (427 Da, Ligand)
Aluminum fluoride (83 Da, Ligand)
Complex of tric/cct-phlp2a treated with atp-alfx (1 MDa, Complex from Homo sapiens)
T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
Phlp2a (pdcl3) (Complex)
Human tric/cct complex (Complex from Homo sapiens)

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EMD-35284

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Human TRiC-PhLP2A complex in the open state

Release date: Jan. 17, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8i9u
Q-score: 0.286

Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH

Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]

Sample:

Adenosine-5'-diphosphate (427 Da, Ligand)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
Complex of human tric/cct and phlp2a (1 MDa, Complex)
T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
Phlp2a (pdcl3) in human tric/cct complex (Complex from Homo sapiens)
Human tric/cct complex (Complex from Homo sapiens)

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EMD-35335

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Human TRiC-PhLP2A-actin complex in the closed state

Release date: Dec. 20, 2023
Resolution: 4.42 Å
EM Method: Single-particle
Fitted PDBs: 8ib8
Q-score: 0.271

Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH

Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]

Sample:

Complex of tric/cct, phlp2a, and actin treated with atp-alfx (1 MDa, Complex)
T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
Human actin (Complex from Homo sapiens)
T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
Actb protein (fragment) (41 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
Phlp2a (pdcl3) (Complex from Homo sapiens)
Human tric/cct complex (Complex from Homo sapiens)

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EMD-32823

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Prefoldin-tubulin-TRiC complex

Release date: Dec. 21, 2022
Resolution: 3.85 Å
EM Method: Single-particle
Fitted PDBs: 7wu7
Q-score: 0.302

Gestaut D, Zhao Y, Park J, Ma B, Leitner A, Collier M, Pintilie G, Roh SH, Chiu W, Frydman J

Cell (2022) 185 pp. 4770-4787.e20 [ DOI: doi:10.1016/j.cell.2022.11.014 Pubmed: 36493755 ]

Sample:

T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
Prefoldin subunit 6 (14 kDa, Protein from Homo sapiens)
Prefoldin subunit 2 (16 kDa, Protein from Homo sapiens)
Prefoldin subunit 5 (16 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
Prefoldin subunit 4 (16 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
Prefoldin subunit 1 (14 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
Prefoldin subunit 3 (22 kDa, Protein from Homo sapiens)
Ternary complex of tric/cct, beta-tubulin, prefoldin complex (1 MDa, Complex from Homo sapiens)

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Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

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Select database:

EMDB [4]

Format:

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Preview first 10

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